Scores & Fixtures 2018 Categoría Primera A
| Round | Wk | Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Apertura Regular Season | 1 | Sat | 2018-02-03 | 16:00 | Rionegro | 0–0 | Pasto | 4,000 | Estadio Alberto Grisales | Carlos Ortega | Match Report | |
| Apertura Regular Season | 1 | Sat | 2018-02-03 | 18:00 | Leones FC | 1–2 | CD América | 5,000 | Estadio Metropolitano de Itagüí | Ferney Trujillo | Match Report | |
| Apertura Regular Season | 1 | Sat | 2018-02-03 | 18:00 | Once Caldas | 2–0 | Jaguares | 7,000 | Estadio Palogrande | Leonard Mosquera | Match Report | |
| Apertura Regular Season | 1 | Fri | 2018-02-02 | 19:45 | Independiente | 3–0 | Huila | 14,596 | Estadio Atanasio Girardot | Heider Castro | Match Report | |
| Apertura Regular Season | 1 | Sun | 2018-02-04 | 15:15 | Junior | 1–0 | CA Bucaramanga | 12,855 | Estadio Metropolitano Roberto Meléndez | Óscar Masegosa | Match Report | |
| Apertura Regular Season | 1 | Sun | 2018-02-04 | 17:15 | Tolima | 0–1 | Nacional | 13,000 | Estadio Manuel Murillo Toro | Éder Vergara | Match Report | |
| Apertura Regular Season | 1 | Sun | 2018-02-04 | 17:30 | Santa Fe | 0–2 | Boyacá Patriot | 9,093 | Estadio Nemesio Camacho El Campín | John J. Ospina | Match Report | |
| Apertura Regular Season | 1 | Sat | 2018-02-03 | 20:00 | AD Cali | 0–0 | Envigado | 6,000 | Estadio Deportivo Cali | Lisandro Castillo | Match Report | |
| Apertura Regular Season | 1 | Sun | 2018-02-04 | 19:30 | Boyacá Chicó | 1–1 | Millonarios | 10,000 | Estadio de la Independencia | Ervin Otero | Match Report | |
| Apertura Regular Season | 1 | Mon | 2018-02-05 | 19:45 | La Equidad | 0–0 | Alianza | 1,000 | Estadio Metropolitano de Techo | Luis Sánchez | Match Report | |
| Apertura Regular Season | 2 | Sat | 2018-02-10 | 16:00 | Huila | 1–0 | AD Cali | 500 | Estadio Manuel Murillo Toro | Ricardo García | Match Report | |
| Apertura Regular Season | 2 | Sat | 2018-02-10 | 18:00 | Alianza | 1–0 | Leones FC | 2,000 | Estadio Daniel Villa Zapata | Nicolás Rodríguez | Match Report | |
| Apertura Regular Season | 2 | Sat | 2018-02-10 | 18:00 | CD América | 1–1 | Tolima | 14,247 | Estadio Olímpico Pascual Guerrero | Carlos Mario Herrera | Match Report | |
| Apertura Regular Season | 2 | Fri | 2018-02-09 | 19:45 | Envigado | 2–0 | Rionegro | 5,000 | Estadio Polideportivo Sur | Bismark Santiago | Match Report | |
| Apertura Regular Season | 2 | Sun | 2018-02-11 | 14:00 | Boyacá Chicó | 1–2 | Independiente | 2,000 | Estadio de la Independencia | Jhon Hinestroza | Match Report | |
| Apertura Regular Season | 2 | Sun | 2018-02-11 | 16:00 | Jaguares | 1–0 | La Equidad | 2,000 | Estadio Armando Tuirán Paternina | Jorge Guzmán | Match Report | |
| Apertura Regular Season | 2 | Sun | 2018-02-11 | 17:15 | Millonarios | 1–0 | Boyacá Patriot | 17,000 | Estadio Nemesio Camacho El Campín | Óscar Masegosa | Match Report | |
| Apertura Regular Season | 2 | Sun | 2018-02-11 | 18:00 | CA Bucaramanga | 1–2 | Once Caldas | 15,000 | Estadio Alfonso López | Never Manjarrés | Match Report | |
| Apertura Regular Season | 2 | Sat | 2018-02-10 | 20:00 | Nacional | 1–0 | Santa Fe | 23,749 | Estadio Atanasio Girardot | Luis Sánchez | Match Report | |
| Apertura Regular Season | 2 | Sun | 2018-02-11 | 20:00 | Pasto | 2–0 | Junior | 7,500 | Estadio Departamental Libertad | Andrés Rojas | Match Report | |
| Apertura Regular Season | 3 | Tue | 2018-02-13 | 18:00 | Rionegro | 0–0 | Huila | 600 | Estadio Alberto Grisales | Ferney Trujillo | Match Report | |
| Apertura Regular Season | 3 | Wed | 2018-02-14 | 16:00 | Leones FC | 0–0 | Jaguares | 500 | Estadio Metropolitano de Itagüí | Ervin Otero | Match Report | |
| Apertura Regular Season | 3 | Wed | 2018-02-14 | 18:00 | AD Cali | 4–0 | Boyacá Chicó | 3,500 | Estadio Deportivo Cali | John J. Ospina | Match Report | |
| Apertura Regular Season | 3 | Tue | 2018-02-13 | 20:00 | Tolima | 3–1 | Alianza | 2,800 | Estadio Manuel Murillo Toro | Diego Escalante | Match Report | |
| Apertura Regular Season | 3 | Thu | 2018-02-15 | 16:00 | La Equidad | 0–0 | CA Bucaramanga | 750 | Estadio Metropolitano de Techo | Wilmar Roldán | Match Report | |
| Apertura Regular Season | 3 | Thu | 2018-02-15 | 18:00 | Once Caldas | 3–0 | Pasto | 9,000 | Estadio Palogrande | Gustavo Murillo | Match Report | |
| Apertura Regular Season | 3 | Wed | 2018-02-14 | 20:00 | Independiente | 1–0 | Millonarios | 21,704 | Estadio Atanasio Girardot | Carlos Betancourt | Match Report | |
| Apertura Regular Season | 3 | Thu | 2018-02-15 | 20:00 | Boyacá Patriot | 3–1 | Nacional | 4,500 | Estadio de la Independencia | Carlos Ortega | Match Report | |
| Apertura Regular Season | 4 | Sat | 2018-02-17 | 16:00 | Jaguares | 2–0 | Tolima | 1,000 | Estadio de Fútbol Jaraguay de Montería | Jhon Hinestroza | Match Report | |
| Apertura Regular Season | 4 | Sat | 2018-02-17 | 18:00 | Independiente | 2–1 | AD Cali | 23,140 | Estadio Atanasio Girardot | Andrés Rojas | Match Report | |
| Apertura Regular Season | 4 | Sat | 2018-02-17 | 18:00 | Boyacá Chicó | 1–2 | Rionegro | 1,200 | Estadio de la Independencia | Éder Vergara | Match Report | |
| Apertura Regular Season | 4 | Sun | 2018-02-18 | 14:00 | Envigado | 1–0 | Once Caldas | 8,000 | Estadio Polideportivo Sur | Ricardo García | Match Report | |
| Apertura Regular Season | 4 | Sun | 2018-02-18 | 16:00 | CA Bucaramanga | 2–2 | Leones FC | 6,000 | Estadio Alfonso López | Heider Castro | Match Report | |
| Apertura Regular Season | 4 | Sun | 2018-02-18 | 17:15 | CD América | 2–0 | Boyacá Patriot | 15,000 | Estadio Olímpico Pascual Guerrero | Wilmar Roldán | Match Report | |
| Apertura Regular Season | 4 | Sun | 2018-02-18 | 18:00 | Huila | 1–0 | Junior | 500 | Estadio Manuel Murillo Toro | Carlos Betancourt | Match Report | |
| Apertura Regular Season | 4 | Sat | 2018-02-17 | 20:00 | Alianza | 2–1 | Santa Fe | 4,000 | Estadio Daniel Villa Zapata | Leonard Mosquera | Match Report | |
| Apertura Regular Season | 4 | Sun | 2018-02-18 | 20:00 | Millonarios | 1–1 | Nacional | 18,600 | Estadio Nemesio Camacho El Campín | Carlos Mario Herrera | Match Report | |
| Apertura Regular Season | 4 | Tue | 2018-02-20 | 19:45 | Pasto | 0–0 | La Equidad | 3,000 | Estadio Departamental Libertad | Bismark Santiago | Match Report | |
| Apertura Regular Season | 5 | Thu | 2018-02-22 | 19:05 | Nacional | 2–0 | CD América | 15,000 | Estadio Atanasio Girardot | Jhon Hinestroza | Match Report | |
| Apertura Regular Season | 5 | Sat | 2018-02-24 | 15:15 | Boyacá Patriot | 2–1 | Alianza | 450 | Estadio de la Independencia | Heider Castro | Match Report | |
| Apertura Regular Season | 5 | Sat | 2018-02-24 | 17:30 | Rionegro | 2–0 | Independiente | 6,300 | Estadio Alberto Grisales | John J. Ospina | Match Report | |
| Apertura Regular Season | 5 | Fri | 2018-02-23 | 19:45 | Leones FC | 2–1 | Pasto | 2,000 | Estadio Metropolitano de Itagüí | Luis Sánchez | Match Report | |
| Apertura Regular Season | 5 | Sun | 2018-02-25 | 14:00 | La Equidad | 1–0 | Envigado | 1,500 | Estadio Metropolitano de Techo | Ervin Otero | Match Report | |
| Apertura Regular Season | 5 | Sun | 2018-02-25 | 16:00 | Once Caldas | 1–0 | Huila | 10,000 | Estadio Palogrande | Diego Escalante | Match Report | |
| Apertura Regular Season | 5 | Sun | 2018-02-25 | 17:15 | Santa Fe | 4–0 | Jaguares | 10,000 | Estadio Nemesio Camacho El Campín | Carlos Betancourt | Match Report | |
| Apertura Regular Season | 5 | Sun | 2018-02-25 | 18:00 | Tolima | 0–1 | CA Bucaramanga | 1,500 | Estadio Manuel Murillo Toro | Nicolás Rodríguez | Match Report | |
| Apertura Regular Season | 5 | Sat | 2018-02-24 | 19:45 | AD Cali | 2–0 | Millonarios | 12,000 | Estadio Olímpico Pascual Guerrero | Gustavo Murillo | Match Report | |
| Apertura Regular Season | 5 | Sun | 2018-02-25 | 20:00 | Junior | 1–0 | Boyacá Chicó | 13,278 | Estadio Metropolitano Roberto Meléndez | Leonard Mosquera | Match Report | |
| Apertura Regular Season | 6 | Sat | 2018-03-03 | 14:00 | Envigado | 1–1 | Leones FC | 1,500 | Estadio Polideportivo Sur | Óscar Masegosa | Match Report | |
| Apertura Regular Season | 6 | Sat | 2018-03-03 | 16:00 | Jaguares | 0–0 | Boyacá Patriot | 2,000 | Estadio de Fútbol Jaraguay de Montería | Nicolás Gallo | Match Report | |
| Apertura Regular Season | 6 | Sat | 2018-03-03 | 18:00 | Huila | 3–1 | La Equidad | 200 | Estadio Manuel Murillo Toro | Leonard Mosquera | Match Report | |
| Apertura Regular Season | 6 | Sat | 2018-03-03 | 18:00 | Alianza | 1–2 | Nacional | 8,000 | Estadio Daniel Villa Zapata | Jorge Guzmán | Match Report | |
| Apertura Regular Season | 6 | Fri | 2018-03-02 | 19:45 | Boyacá Chicó | 2–2 | Once Caldas | 1,200 | Estadio de la Independencia | Bismark Santiago | Match Report | |
| Apertura Regular Season | 6 | Sun | 2018-03-04 | 15:15 | Millonarios | 3–1 | CD América | 18,483 | Estadio Nemesio Camacho El Campín | John J. Ospina | Match Report | |
| Apertura Regular Season | 6 | Sun | 2018-03-04 | 17:15 | Independiente | 1–2 | Junior | 22,343 | Estadio Atanasio Girardot | Ervin Otero | Match Report | |
| Apertura Regular Season | 6 | Sun | 2018-03-04 | 17:30 | Pasto | 1–1 | Tolima | 5,500 | Estadio Departamental Libertad | Wilmar Roldán | Match Report | |
| Apertura Regular Season | 6 | Sat | 2018-03-03 | 20:00 | AD Cali | 4–0 | Rionegro | 8,000 | Estadio Olímpico Pascual Guerrero | Jhon Hinestroza | Match Report | |
| Apertura Regular Season | 6 | Sun | 2018-03-04 | 19:30 | CA Bucaramanga | 1–0 | Santa Fe | 1,300 | Estadio Alfonso López | Gustavo Murillo | Match Report | |
| Apertura Regular Season | 7 | Tue | 2018-03-06 | 18:00 | Leones FC | 0–0 | Huila | 2,500 | Estadio Metropolitano de Itagüí | Never Manjarrés | Match Report | |
| Apertura Regular Season | 7 | Wed | 2018-03-07 | 18:00 | Once Caldas | 3–2 | Independiente | 13,000 | Estadio Palogrande | Luis Sánchez | Match Report | |
| Apertura Regular Season | 7 | Tue | 2018-03-06 | 20:00 | La Equidad | 4–0 | Boyacá Chicó | 1,000 | Estadio Metropolitano de Techo | Carlos Ortega | Match Report | |
| Apertura Regular Season | 7 | Thu | 2018-03-08 | 16:00 | Boyacá Patriot | 1–0 | CA Bucaramanga | 1,300 | Estadio de la Independencia | Carlos Betancourt | Match Report | |
| Apertura Regular Season | 7 | Thu | 2018-03-08 | 18:00 | Santa Fe | 1–0 | Pasto | 6,680 | Estadio Nemesio Camacho El Campín | Diego Escalante | Match Report | |
| Apertura Regular Season | 7 | Wed | 2018-03-07 | 20:00 | Nacional | 1–0 | Jaguares | 14,177 | Estadio Atanasio Girardot | Andrés Rojas | Match Report | |
| Apertura Regular Season | 7 | Thu | 2018-03-08 | 19:00 | Tolima | 2–1 | Envigado | 1,200 | Estadio Manuel Murillo Toro | Heider Castro | Match Report | |
| Apertura Regular Season | 7 | Thu | 2018-03-08 | 20:00 | Rionegro | 3–1 | Millonarios | 3,500 | Estadio Alberto Grisales | Ricardo García | Match Report | |
| Apertura Regular Season | 7 | Fri | 2018-03-09 | 20:00 | Junior | 2–1 | AD Cali | 15,729 | Estadio Metropolitano Roberto Meléndez | Nicolás Gallo | Match Report | |
| Apertura Regular Season | 8 | Tue | 2018-03-13 | 18:00 | Boyacá Chicó | 1–1 | Leones FC | 800 | Estadio de la Independencia | Carlos Mario Herrera | Match Report | |
| Apertura Regular Season | 8 | Wed | 2018-03-14 | 18:00 | Pasto | 1–1 | Boyacá Patriot | 2,500 | Estadio Departamental Libertad | Ferney Trujillo | Match Report | |
| Apertura Regular Season | 8 | Wed | 2018-03-14 | 18:00 | Envigado | 0–3 | Santa Fe | 2,000 | Estadio Polideportivo Sur | Luis Sánchez | Match Report | |
| Apertura Regular Season | 8 | Tue | 2018-03-13 | 20:00 | Independiente | 1–0 | La Equidad | 16,300 | Estadio Atanasio Girardot | Éder Vergara | Match Report | |
| Apertura Regular Season | 8 | Thu | 2018-03-15 | 18:00 | Rionegro | 0–0 | Junior | 3,000 | Estadio Alberto Grisales | Andrés Rojas | Match Report | |
| Apertura Regular Season | 8 | Wed | 2018-03-14 | 20:00 | AD Cali | 2–1 | Once Caldas | 8,000 | Estadio Olímpico Pascual Guerrero | Ervin Otero | Match Report | |
| Apertura Regular Season | 8 | Thu | 2018-03-15 | 20:00 | Jaguares | 1–0 | CD América | 12,000 | Estadio de Fútbol Jaraguay de Montería | Nicolás Rodríguez | Match Report | |
| Apertura Regular Season | 9 | Sat | 2018-03-17 | 17:30 | Tolima | 1–0 | Boyacá Chicó | 2,600 | Estadio Manuel Murillo Toro | Lisandro Castillo | Match Report | |
| Apertura Regular Season | 9 | Sat | 2018-03-17 | 18:00 | Santa Fe | 0–1 | Huila | 8,886 | Estadio Nemesio Camacho El Campín | Carlos Mario Herrera | Match Report | |
| Apertura Regular Season | 9 | Sun | 2018-03-18 | 14:00 | Boyacá Patriot | 1–0 | Envigado | 2,000 | Estadio de la Independencia | Andrés Rojas | Match Report | |
| Apertura Regular Season | 9 | Sun | 2018-03-18 | 16:00 | La Equidad | 2–0 | AD Cali | 1,500 | Estadio Metropolitano de Techo | Diego Escalante | Match Report | |
| Apertura Regular Season | 9 | Sun | 2018-03-18 | 17:15 | Junior | 2–0 | Millonarios | 19,167 | Estadio Metropolitano Roberto Meléndez | Luis Sánchez | Match Report | |
| Apertura Regular Season | 9 | Sun | 2018-03-18 | 18:00 | Alianza | 4–0 | Jaguares | 3,000 | Estadio Daniel Villa Zapata | John J. Ospina | Match Report | |
| Apertura Regular Season | 9 | Sat | 2018-03-17 | 19:45 | Nacional | 2–0 | Pasto | 20,315 | Estadio Atanasio Girardot | Ricardo García | Match Report | |
| Apertura Regular Season | 9 | Mon | 2018-03-19 | 15:15 | Leones FC | 0–2 | Independiente | 8,000 | Estadio Metropolitano de Itagüí | Carlos Ortega | Match Report | |
| Apertura Regular Season | 9 | Sun | 2018-03-18 | 20:00 | CD América | 2–1 | CA Bucaramanga | 7,257 | Estadio Olímpico Pascual Guerrero | Nicolás Gallo | Match Report | |
| Apertura Regular Season | 9 | Mon | 2018-03-19 | 19:30 | Once Caldas | 1–2 | Rionegro | 7,500 | Estadio Palogrande | Heider Castro | Match Report | |
| Apertura Regular Season | 8 | Thu | 2018-03-22 | 18:00 | Millonarios | 1–1 | Alianza | 8,388 | Estadio Nemesio Camacho El Campín | Éder Vergara | Match Report | |
| Apertura Regular Season | 3 | Wed | 2018-03-21 | 20:00 | Junior | 0–3 | Envigado | 11,809 | Estadio Metropolitano Roberto Meléndez | Gustavo Murillo | Match Report | |
| Apertura Regular Season | 3 | Wed | 2018-03-21 | 20:05 | Santa Fe | 3–0 | CD América | 11,186 | Estadio Nemesio Camacho El Campín | Bismark Santiago | Match Report | |
| Apertura Regular Season | 8 | Thu | 2018-03-22 | 20:00 | CA Bucaramanga | 0–0 | Nacional | 23,000 | Estadio Alfonso López | Jhon Hinestroza | Match Report | |
| Apertura Regular Season | 10 | Sat | 2018-03-24 | 14:00 | Rionegro | 2–1 | La Equidad | 4,500 | Estadio Alberto Grisales | Ervin Otero | Match Report | |
| Apertura Regular Season | 10 | Sat | 2018-03-24 | 16:00 | Boyacá Chicó | 3–1 | Santa Fe | 4,600 | Estadio de la Independencia | Heider Castro | Match Report | |
| Apertura Regular Season | 10 | Sat | 2018-03-24 | 18:00 | Independiente | 2–2 | Tolima | 18,417 | Estadio Atanasio Girardot | Andrés Rojas | Match Report | |
| Apertura Regular Season | 10 | Sat | 2018-03-24 | 18:00 | Junior | 3–0 | Once Caldas | 13,309 | Estadio Metropolitano Roberto Meléndez | Wilmar Roldán | Match Report | |
| Apertura Regular Season | 10 | Fri | 2018-03-23 | 19:00 | AD Cali | 2–1 | Leones FC | 6,000 | Estadio Olímpico Pascual Guerrero | Nicolás Rodríguez | Match Report | |
| Apertura Regular Season | 10 | Sun | 2018-03-25 | 15:15 | CA Bucaramanga | 4–1 | Alianza | 3,000 | Estadio Alfonso López | Diego Escalante | Match Report | |
| Apertura Regular Season | 10 | Sun | 2018-03-25 | 17:15 | Envigado | 2–2 | Nacional | 5,000 | Estadio Polideportivo Sur | Nolberto Ararat | Match Report | |
| Apertura Regular Season | 10 | Sun | 2018-03-25 | 17:30 | Huila | 2–0 | Boyacá Patriot | 2,000 | Estadio Manuel Murillo Toro | John J. Ospina | Match Report | |
| Apertura Regular Season | 10 | Sat | 2018-03-24 | 20:00 | Pasto | 2–0 | CD América | 8,500 | Estadio Departamental Libertad | Leonard Mosquera | Match Report | |
| Apertura Regular Season | 10 | Sun | 2018-03-25 | 19:30 | Millonarios | 1–1 | Jaguares | 10,000 | Estadio Nemesio Camacho El Campín | Óscar Masegosa | Match Report | |
| Apertura Regular Season | 11 | Tue | 2018-03-27 | 18:00 | Tolima | 0–1 | AD Cali | 2,000 | Estadio Manuel Murillo Toro | Éder Vergara | Match Report | |
| Apertura Regular Season | 11 | Wed | 2018-03-28 | 14:00 | Leones FC | 1–1 | Rionegro | 1,000 | Estadio Metropolitano de Itagüí | Edilson Ariza | Match Report | |
| Apertura Regular Season | 11 | Wed | 2018-03-28 | 16:00 | CD América | 0–1 | Envigado | 3,000 | Estadio Olímpico Pascual Guerrero | Carlos Ortega | Match Report | |
| Apertura Regular Season | 11 | Wed | 2018-03-28 | 18:00 | La Equidad | 0–0 | Junior | 2,000 | Estadio Metropolitano de Techo | Luis Trujillo | Match Report | |
| Apertura Regular Season | 11 | Tue | 2018-03-27 | 20:00 | Santa Fe | 1–0 | Independiente | 6,321 | Estadio Nemesio Camacho El Campín | Ricardo García | Match Report | |
| Apertura Regular Season | 11 | Thu | 2018-03-29 | 15:15 | Boyacá Patriot | 2–0 | Boyacá Chicó | 4,500 | Estadio de la Independencia | Gustavo Murillo | Match Report | |
| Apertura Regular Season | 11 | Thu | 2018-03-29 | 17:00 | Once Caldas | 0–1 | Millonarios | 13,000 | Estadio Palogrande | Jhon Hinestroza | Match Report | |
| Apertura Regular Season | 11 | Thu | 2018-03-29 | 17:30 | Jaguares | 0–1 | CA Bucaramanga | 4,000 | Estadio de Fútbol Jaraguay de Montería | Harold Perilla | Match Report | |
| Apertura Regular Season | 11 | Wed | 2018-03-28 | 20:00 | Nacional | 1–0 | Huila | 15,000 | Estadio Atanasio Girardot | Leevan Suárez | Match Report | |
| Apertura Regular Season | 11 | Thu | 2018-03-29 | 19:30 | Alianza | 0–2 | Pasto | 3,000 | Estadio Daniel Villa Zapata | Carlos Mario Herrera | Match Report | |
| Apertura Regular Season | 12 | Sat | 2018-03-31 | 15:15 | Rionegro | 1–3 | Tolima | 3,000 | Estadio Alberto Grisales | Luis Sánchez | Match Report | |
| Apertura Regular Season | 12 | Sat | 2018-03-31 | 17:30 | Junior | 1–0 | Leones FC | 10,931 | Estadio Metropolitano Roberto Meléndez | Nolberto Ararat | Match Report | |
| Apertura Regular Season | 12 | Sat | 2018-03-31 | 18:00 | Huila | 4–0 | CD América | 1,500 | Estadio Manuel Murillo Toro | Diego Escalante | Match Report | |
| Apertura Regular Season | 12 | Sun | 2018-04-01 | 14:00 | Pasto | 0–1 | Jaguares | 5,500 | Estadio Departamental Libertad | Jorge Duarte | Match Report | |
| Apertura Regular Season | 12 | Sun | 2018-04-01 | 16:00 | Once Caldas | 3–2 | La Equidad | 7,300 | Estadio Palogrande | John J. Ospina | Match Report | |
| Apertura Regular Season | 12 | Sun | 2018-04-01 | 17:15 | Millonarios | 4–1 | CA Bucaramanga | 10,876 | Estadio Nemesio Camacho El Campín | Ferney Trujillo | Match Report | |
| Apertura Regular Season | 12 | Sun | 2018-04-01 | 18:00 | Independiente | 4–1 | Boyacá Patriot | 15,000 | Estadio Atanasio Girardot | Ervin Otero | Match Report | |
| Apertura Regular Season | 12 | Sat | 2018-03-31 | 19:45 | AD Cali | 3–0 | Santa Fe | 13,000 | Estadio Olímpico Pascual Guerrero | Leonard Mosquera | Match Report | |
| Apertura Regular Season | 12 | Sun | 2018-04-01 | 20:00 | Boyacá Chicó | 1–1 | Nacional | 5,000 | Estadio de la Independencia | Andrés Rojas | Match Report | |
| Apertura Regular Season | 12 | Mon | 2018-04-02 | 20:00 | Envigado | 0–0 | Alianza | 1,000 | Estadio Polideportivo Sur | Leevan Suárez | Match Report | |
| Apertura Regular Season | 8 | Wed | 2018-04-04 | 19:30 | Huila | 0–0 | Tolima | 1,000 | Estadio Manuel Murillo Toro | Nolberto Ararat | Match Report | |
| Apertura Regular Season | 13 | Fri | 2018-04-06 | 18:00 | Jaguares | 2–4 | Envigado | 4,000 | Estadio de Fútbol Jaraguay de Montería | Carlos Mario Herrera | Match Report | |
| Apertura Regular Season | 13 | Sat | 2018-04-07 | 14:00 | Leones FC | 0–1 | Once Caldas | 1,000 | Estadio Metropolitano de Itagüí | Ferney Trujillo | Match Report | |
| Apertura Regular Season | 13 | Sat | 2018-04-07 | 16:00 | CA Bucaramanga | 3–1 | Pasto | 5,000 | Estadio Alfonso López | Éder Vergara | Match Report | |
| Apertura Regular Season | 13 | Sat | 2018-04-07 | 18:00 | Alianza | 2–1 | Huila | 3,000 | Estadio Daniel Villa Zapata | Nicolás Gallo | Match Report | |
| Apertura Regular Season | 13 | Sat | 2018-04-07 | 18:00 | CD América | 3–0 | Boyacá Chicó | 5,579 | Estadio Olímpico Pascual Guerrero | Wilmar Roldán | Match Report | |
| Apertura Regular Season | 13 | Fri | 2018-04-06 | 20:00 | Boyacá Patriot | 1–3 | AD Cali | 4,500 | Estadio de la Independencia | Diego Escalante | Match Report | |
| Apertura Regular Season | 13 | Sun | 2018-04-08 | 17:15 | Nacional | 2–0 | Independiente | 41,746 | Estadio Atanasio Girardot | Bismark Santiago | Match Report | |
| Apertura Regular Season | 13 | Sun | 2018-04-08 | 17:30 | Santa Fe | 0–0 | Rionegro | 6,977 | Estadio Nemesio Camacho El Campín | John J. Ospina | Match Report | |
| Apertura Regular Season | 13 | Sat | 2018-04-07 | 20:00 | La Equidad | 0–0 | Millonarios | 2,000 | Estadio Metropolitano de Techo | Gustavo Murillo | Match Report | |
| Apertura Regular Season | 13 | Sun | 2018-04-08 | 19:30 | Tolima | 2–1 | Junior | 4,000 | Estadio Manuel Murillo Toro | Jhon Hinestroza | Match Report | |
| Apertura Regular Season | 14 | Tue | 2018-04-10 | 16:00 | La Equidad | 2–0 | Leones FC | 500 | Estadio Metropolitano de Techo | Ricardo García | Match Report | |
| Apertura Regular Season | 14 | Tue | 2018-04-10 | 18:00 | Boyacá Chicó | 3–0 | Alianza | 500 | Estadio de la Independencia | Harold Perilla | Match Report | |
| Apertura Regular Season | 14 | Wed | 2018-04-11 | 16:00 | Envigado | 1–1 | CA Bucaramanga | 1,500 | Estadio Polideportivo Sur | Jorge Guzmán | Match Report | |
| Apertura Regular Season | 14 | Wed | 2018-04-11 | 18:00 | Once Caldas | 0–1 | Tolima | 8,500 | Estadio Palogrande | Carlos Ortega | Match Report | |
| Apertura Regular Season | 14 | Tue | 2018-04-10 | 20:00 | Millonarios | 2–0 | Pasto | 8,580 | Estadio Nemesio Camacho El Campín | Heider Castro | Match Report | |
| Apertura Regular Season | 14 | Wed | 2018-04-11 | 20:00 | Junior | 1–1 | Santa Fe | 12,727 | Estadio Metropolitano Roberto Meléndez | Ervin Otero | Match Report | |
| Apertura Regular Season | 14 | Thu | 2018-04-12 | 20:00 | Rionegro | 0–1 | Boyacá Patriot | 100 | Estadio Alberto Grisales | Nolberto Ararat | Match Report | |
| Apertura Regular Season | 15 | Sat | 2018-04-14 | 14:00 | Tolima | 4–1 | La Equidad | 1,500 | Estadio Manuel Murillo Toro | Edilson Ariza | Match Report | |
| Apertura Regular Season | 15 | Sat | 2018-04-14 | 16:00 | Jaguares | 2–0 | Boyacá Chicó | 600 | Estadio de Fútbol Jaraguay de Montería | John J. Ospina | Match Report | |
| Apertura Regular Season | 15 | Sat | 2018-04-14 | 17:30 | Santa Fe | 2–2 | Once Caldas | 7,281 | Estadio Nemesio Camacho El Campín | Wilmar Roldán | Match Report | |
| Apertura Regular Season | 15 | Sat | 2018-04-14 | 18:00 | CA Bucaramanga | 0–1 | Huila | 5,000 | Estadio Alfonso López | Luis Sánchez | Match Report | |
| Apertura Regular Season | 15 | Sun | 2018-04-15 | 14:00 | Pasto | 2–0 | Envigado | 1,000 | Estadio Departamental Libertad | Gustavo Murillo | Match Report | |
| Apertura Regular Season | 15 | Sun | 2018-04-15 | 16:00 | Alianza | 2–2 | Independiente | 2,000 | Estadio Daniel Villa Zapata | Jhon Hinestroza | Match Report | |
| Apertura Regular Season | 15 | Sun | 2018-04-15 | 18:00 | Boyacá Patriot | 1–0 | Junior | 5,000 | Estadio de la Independencia | Ricardo García | Match Report | |
| Apertura Regular Season | 15 | Sat | 2018-04-14 | 20:00 | Leones FC | 2–1 | Millonarios | 3,000 | Estadio Metropolitano de Itagüí | Leevan Suárez | Match Report | |
| Apertura Regular Season | 15 | Sat | 2018-04-14 | 20:00 | CD América | 2–1 | AD Cali | 15,600 | Estadio Olímpico Pascual Guerrero | Andrés Rojas | Match Report | |
| Apertura Regular Season | 15 | Sun | 2018-04-15 | 20:00 | Nacional | 1–0 | Rionegro | 18,090 | Estadio Atanasio Girardot | Nicolás Gallo | Match Report | |
| Apertura Regular Season | 16 | Tue | 2018-04-17 | 18:00 | Leones FC | 0–1 | Tolima | 10,000 | Estadio Metropolitano de Itagüí | Heider Castro | Match Report | |
| Apertura Regular Season | 16 | Wed | 2018-04-18 | 16:00 | Huila | 2–0 | Pasto | 1,000 | Estadio Guillermo Plazas Alcid | Jorge Guzmán | Match Report | |
| Apertura Regular Season | 16 | Wed | 2018-04-18 | 18:00 | Once Caldas | 2–0 | Boyacá Patriot | 9,000 | Estadio Palogrande | Nolberto Ararat | Match Report | |
| Apertura Regular Season | 16 | Tue | 2018-04-17 | 20:00 | Boyacá Chicó | 2–1 | CA Bucaramanga | 650 | Estadio de la Independencia | Diego Escalante | Match Report | |
| Apertura Regular Season | 16 | Thu | 2018-04-19 | 18:00 | AD Cali | 2–1 | Alianza | 5,000 | Estadio Deportivo Cali | John J. Ospina | Match Report | |
| Apertura Regular Season | 16 | Wed | 2018-04-18 | 20:00 | Independiente | 2–1 | Jaguares | 13,687 | Estadio Atanasio Girardot | Edilson Ariza | Match Report | |
| Apertura Regular Season | 16 | Thu | 2018-04-19 | 20:00 | Rionegro | 2–1 | CD América | 3,500 | Estadio Alberto Grisales | Ervin Otero | Match Report | |
| Apertura Regular Season | 17 | Sat | 2018-04-21 | 15:15 | Boyacá Patriot | 0–0 | La Equidad | 800 | Estadio de la Independencia | Carlos Mario Herrera | Match Report | |
| Apertura Regular Season | 17 | Sat | 2018-04-21 | 17:30 | Tolima | 1–0 | Millonarios | 12,000 | Estadio Manuel Murillo Toro | Bismark Santiago | Match Report | |
| Apertura Regular Season | 17 | Sat | 2018-04-21 | 18:00 | CA Bucaramanga | 2–4 | Independiente | 5,000 | Estadio Alfonso López | Ferney Trujillo | Match Report | |
| Apertura Regular Season | 17 | Sun | 2018-04-22 | 14:00 | Envigado | 0–3 | Huila | 3,000 | Estadio Polideportivo Sur | Andrés Rojas | Match Report | |
| Apertura Regular Season | 17 | Sun | 2018-04-22 | 16:00 | Jaguares | 1–0 | AD Cali | 1,000 | Estadio de Fútbol Jaraguay de Montería | Ricardo García | Match Report | |
| Apertura Regular Season | 17 | Sun | 2018-04-22 | 17:15 | CD América | 2–2 | Junior | 11,300 | Estadio Olímpico Pascual Guerrero | Nicolás Gallo | Match Report | |
| Apertura Regular Season | 17 | Sun | 2018-04-22 | 18:00 | Alianza | 2–0 | Rionegro | 2,500 | Estadio Daniel Villa Zapata | Never Manjarrés | Match Report | |
| Apertura Regular Season | 17 | Sat | 2018-04-21 | 19:45 | Nacional | 1–0 | Once Caldas | 24,017 | Estadio Atanasio Girardot | Luis Sánchez | Match Report | |
| Apertura Regular Season | 17 | Sun | 2018-04-22 | 20:00 | Santa Fe | 2–1 | Leones FC | 4,469 | Estadio Nemesio Camacho El Campín | Éder Vergara | Match Report | |
| Apertura Regular Season | 17 | Mon | 2018-04-23 | 20:00 | Pasto | 3–0 | Boyacá Chicó | 1,500 | Estadio Departamental Libertad | Jhon Hinestroza | Match Report | |
| Apertura Regular Season | 14 | Wed | 2018-04-25 | 18:00 | Huila | 1–2 | Jaguares | 600 | Estadio Guillermo Plazas Alcid | Lisandro Castillo | Match Report | |
| Apertura Regular Season | 16 | Thu | 2018-04-26 | 18:00 | La Equidad | 2–0 | Santa Fe | 634 | Estadio Metropolitano de Techo | Diego Escalante | Match Report | |
| Apertura Regular Season | 16 | Wed | 2018-04-25 | 20:00 | Junior | 1–1 | Nacional | 15,095 | Estadio Metropolitano Roberto Meléndez | Gustavo Murillo | Match Report | |
| Apertura Regular Season | 7 | Thu | 2018-04-26 | 20:00 | CD América | 2–1 | Alianza | 6,000 | Estadio Olímpico Pascual Guerrero | Bismark Santiago | Match Report | |
| Apertura Regular Season | 18 | Sat | 2018-04-28 | 14:00 | Boyacá Chicó | 0–1 | Envigado | 500 | Estadio de la Independencia | Jorge Duarte | Match Report | |
| Apertura Regular Season | 18 | Sat | 2018-04-28 | 16:00 | Rionegro | 1–1 | Jaguares | 5,000 | Estadio Alberto Grisales | Carlos Betancourt | Match Report | |
| Apertura Regular Season | 18 | Sat | 2018-04-28 | 18:00 | Millonarios | 1–0 | Huila | 10,928 | Estadio Nemesio Camacho El Campín | Jhon Hinestroza | Match Report | |
| Apertura Regular Season | 18 | Fri | 2018-04-27 | 20:00 | AD Cali | 0–1 | CA Bucaramanga | 5,000 | Estadio Olímpico Pascual Guerrero | Leevan Suárez | Match Report | |
| Apertura Regular Season | 18 | Sun | 2018-04-29 | 14:00 | Leones FC | 1–1 | Boyacá Patriot | 4,000 | Estadio Metropolitano de Itagüí | Luis Sánchez | Match Report | |
| Apertura Regular Season | 18 | Sun | 2018-04-29 | 16:00 | Tolima | 0–0 | Santa Fe | 8,000 | Estadio Manuel Murillo Toro | Nolberto Ararat | Match Report | |
| Apertura Regular Season | 18 | Sun | 2018-04-29 | 17:15 | Junior | 0–0 | Alianza | 22,050 | Estadio Metropolitano Roberto Meléndez | Ferney Trujillo | Match Report | |
| Apertura Regular Season | 18 | Sun | 2018-04-29 | 18:00 | La Equidad | 1–0 | Nacional | 6,000 | Estadio Metropolitano de Techo | John J. Ospina | Match Report | |
| Apertura Regular Season | 18 | Sat | 2018-04-28 | 20:00 | Independiente | 1–0 | Pasto | 14,266 | Estadio Atanasio Girardot | Luis Trujillo | Match Report | |
| Apertura Regular Season | 18 | Sun | 2018-04-29 | 20:00 | Once Caldas | 2–2 | CD América | 20,000 | Estadio Palogrande | Carlos Mario Herrera | Match Report | |
| Apertura Regular Season | 16 | Wed | 2018-05-02 | 18:00 | Millonarios | 1–0 | Envigado | 9,213 | Estadio Nemesio Camacho El Campín | John J. Ospina | Match Report | |
| Apertura Regular Season | 14 | Wed | 2018-05-02 | 20:00 | AD Cali | 0–2 | Nacional | 18,000 | Estadio Olímpico Pascual Guerrero | Carlos Mario Herrera | Match Report | |
| Apertura Regular Season | 14 | Thu | 2018-05-03 | 20:00 | Independiente | 3–1 | CD América | 17,000 | Estadio Atanasio Girardot | Heider Castro | Match Report | |
| Apertura Regular Season | 19 | Sun | 2018-05-06 | 14:00 | Envigado | 2–0 | Independiente | 3,500 | Estadio Polideportivo Sur | Carlos Betancourt | Match Report | |
| Apertura Regular Season | 19 | Sun | 2018-05-06 | 16:00 | Huila | 0–1 | Boyacá Chicó | 600 | Estadio Guillermo Plazas Alcid | Edilson Ariza | Match Report | |
| Apertura Regular Season | 19 | Sun | 2018-05-06 | 18:00 | Santa Fe | 1–0 | Millonarios | 19,214 | Estadio Nemesio Camacho El Campín | Gustavo Murillo | Match Report | |
| Apertura Regular Season | 19 | Sun | 2018-05-06 | 18:00 | Boyacá Patriot | 0–0 | Tolima | 2,200 | Estadio de la Independencia | Jorge Guzmán | Match Report | |
| Apertura Regular Season | 19 | Sun | 2018-05-06 | 18:00 | CA Bucaramanga | 2–2 | Rionegro | 3,000 | Estadio Alfonso López | Andrés Rojas | Match Report | |
| Apertura Regular Season | 19 | Sun | 2018-05-06 | 18:00 | Pasto | 0–0 | AD Cali | 18,000 | Estadio Departamental Libertad | Diego Escalante | Match Report | |
| Apertura Regular Season | 19 | Sun | 2018-05-06 | 18:00 | CD América | 1–1 | La Equidad | 3,000 | Estadio Olímpico Pascual Guerrero | Ricardo García | Match Report | |
| Apertura Regular Season | 19 | Sun | 2018-05-06 | 18:00 | Jaguares | 1–2 | Junior | 8,000 | Estadio de Fútbol Jaraguay de Montería | Wilmar Roldán | Match Report | |
| Apertura Regular Season | 19 | Sun | 2018-05-06 | 18:00 | Alianza | 4–1 | Once Caldas | 2,000 | Estadio Daniel Villa Zapata | Jhon Hinestroza | Match Report | |
| Apertura Regular Season | 19 | Sun | 2018-05-06 | 20:00 | Nacional | 1–0 | Leones FC | 18,659 | Estadio Atanasio Girardot | Nolberto Ararat | Match Report | |
| Quarter-finals | Sat | 2018-05-12 | 18:00 | Boyacá Patriot | 1–1 | Huila | 2,500 | Estadio Guillermo Plazas Alcid | Bismark Santiago | Match Report | Leg 1 of 2 | |
| Quarter-finals | Sun | 2018-05-13 | 17:15 | Junior | 0–1 | Independiente | 16,309 | Estadio Metropolitano Roberto Meléndez | Jhon Hinestroza | Match Report | Leg 1 of 2 | |
| Quarter-finals | Sat | 2018-05-12 | 20:00 | AD Cali | 1–0 | Nacional | 24,000 | Estadio Deportivo Cali | Nicolás Gallo | Match Report | Leg 1 of 2 | |
| Quarter-finals | Sun | 2018-05-13 | 19:30 | Once Caldas | 1–0 | Tolima | 9,500 | Estadio Palogrande | Wilmar Roldán | Match Report | Leg 1 of 2 | |
| Quarter-finals | Sat | 2018-05-19 | 18:00 | Nacional | 2–0 | AD Cali | 31,114 | Estadio Atanasio Girardot | Gustavo Murillo | Match Report | Leg 2 of 2; Nacional won | |
| Quarter-finals | Sun | 2018-05-20 | 17:15 | Tolima | 3–0 | Once Caldas | 15,000 | Estadio Manuel Murillo Toro | Carlos Betancourt | Match Report | Leg 2 of 2; Tolima won | |
| Quarter-finals | Sat | 2018-05-19 | 20:00 | Huila | (3) 0–0 (1) | Boyacá Patriot | 2,000 | Estadio de la Independencia | Andrés Rojas | Match Report | Leg 2 of 2; Huila won; Huila won on penalty kicks following extra time | |
| Quarter-finals | Sun | 2018-05-20 | 19:30 | Independiente | 2–2 | Junior | 17,763 | Estadio Atanasio Girardot | Luis Sánchez | Match Report | Leg 2 of 2; Independiente won | |
| Semi-finals | Tue | 2018-05-29 | 19:45 | Huila | 0–0 | Nacional | 29,308 | Estadio Nemesio Camacho El Campín | John J. Ospina | Match Report | Leg 1 of 2 | |
| Semi-finals | Wed | 2018-05-30 | 19:30 | Tolima | 1–0 | Independiente | 16,000 | Estadio Manuel Murillo Toro | Jhon Hinestroza | Match Report | Leg 1 of 2 | |
| Semi-finals | Sat | 2018-06-02 | 18:00 | Nacional | (4) 0–0 (2) | Huila | 24,270 | Estadio Atanasio Girardot | Carlos Betancourt | Match Report | Leg 2 of 2; Nacional won; Nacional won on penalty kicks following extra time | |
| Semi-finals | Sun | 2018-06-03 | 17:30 | Independiente | (3) 1–0 (5) | Tolima | 18,398 | Estadio Atanasio Girardot | Nicolás Gallo | Match Report | Leg 2 of 2; Tolima won | |
| Finals | Wed | 2018-06-06 | 19:30 | Tolima | 0–1 | Nacional | 25,000 | Estadio Manuel Murillo Toro | Andrés Rojas | Match Report | Leg 1 of 2 | |
| Finals | Sat | 2018-06-09 | 19:15 | Nacional | (2) 1–2 (4) | Tolima | 44,695 | Estadio Atanasio Girardot | Luis Sánchez | Match Report | Leg 2 of 2; Tolima won; Tolima won on penalty kicks following extra time | |
| Regular season | 1 | Fri | 2018-07-20 | 17:00 | Alianza | 0–2 | La Equidad | 4,000 | Estadio Daniel Villa Zapata | Jorge Tabares | Match Report | |
| Regular season | 1 | Sat | 2018-07-21 | 17:30 | Pasto | 0–1 | Rionegro | 4,000 | Estadio Departamental Libertad | Luis Trujillo | Match Report | |
| Regular season | 1 | Sat | 2018-07-21 | 18:00 | CA Bucaramanga | 0–0 | Junior | 7,000 | Estadio Alfonso López | Nolberto Ararat | Match Report | |
| Regular season | 1 | Sun | 2018-07-22 | 15:00 | Boyacá Patriot | 0–0 | Santa Fe | 6,500 | Estadio de la Independencia | Ferney Trujillo | Match Report | |
| Regular season | 1 | Sun | 2018-07-22 | 17:00 | Jaguares | 0–1 | Once Caldas | 1,000 | Estadio de Fútbol Jaraguay de Montería | Óscar Masegosa | Match Report | |
| Regular season | 1 | Sun | 2018-07-22 | 17:15 | Millonarios | 2–2 | Boyacá Chicó | 10,000 | Estadio Nemesio Camacho El Campín | Diego Escalante | Match Report | |
| Regular season | 1 | Sat | 2018-07-21 | 19:45 | Envigado | 1–1 | AD Cali | 2,000 | Estadio Polideportivo Sur | Bismark Santiago | Match Report | |
| Regular season | 1 | Tue | 2018-07-24 | 18:00 | Huila | 0–0 | Independiente | 1,000 | Estadio Guillermo Plazas Alcid | Mauricio Palencia | Match Report | |
| Regular season | 1 | Tue | 2018-07-24 | 20:00 | CD América | 1–0 | Leones FC | 5,211 | Estadio Olímpico Pascual Guerrero | Jorge Guzmán | Match Report | |
| Regular season | 1 | Wed | 2018-07-25 | 19:45 | Nacional | 1–2 | Tolima | 16,175 | Estadio Atanasio Girardot | Heider Castro | Match Report | |
| Regular season | 2 | Fri | 2018-07-27 | 18:00 | La Equidad | 2–0 | Jaguares | 2,000 | Estadio Metropolitano de Techo | Edilson Ariza | Match Report | |
| Regular season | 2 | Sat | 2018-07-28 | 15:15 | Rionegro | 1–1 | Envigado | 1,000 | Estadio Alberto Grisales | Éder Vergara | Match Report | |
| Regular season | 2 | Sat | 2018-07-28 | 17:30 | AD Cali | 1–0 | Huila | 8,000 | Estadio Deportivo Cali | Carlos Ortega | Match Report | |
| Regular season | 2 | Sat | 2018-07-28 | 18:00 | Santa Fe | 0–2 | Nacional | 16,004 | Estadio Nemesio Camacho El Campín | Carlos Betancourt | Match Report | |
| Regular season | 2 | Fri | 2018-07-27 | 20:00 | Once Caldas | 2–1 | CA Bucaramanga | 5,500 | Estadio Palogrande | Nicolás Rodríguez | Match Report | |
| Regular season | 2 | Sun | 2018-07-29 | 17:15 | Junior | 3–0 | Pasto | 7,465 | Estadio Metropolitano Roberto Meléndez | Lisandro Castillo | Match Report | |
| Regular season | 2 | Sun | 2018-07-29 | 17:30 | Boyacá Patriot | 0–2 | Millonarios | 10,050 | Estadio de la Independencia | Ricardo García | Match Report | |
| Regular season | 2 | Sat | 2018-07-28 | 19:45 | Tolima | 1–0 | CD América | 1,207 | Estadio Manuel Murillo Toro | Gustavo Murillo | Match Report | |
| Regular season | 2 | Sun | 2018-07-29 | 19:30 | Independiente | 2–0 | Boyacá Chicó | 14,000 | Estadio Atanasio Girardot | Carlos Mario Herrera | Match Report | |
| Regular season | 2 | Mon | 2018-07-30 | 20:00 | Leones FC | 0–1 | Alianza | 1,000 | Estadio Metropolitano de Itagüí | Nicolás Gallo | Match Report | |
| Regular season | 3 | Wed | 2018-08-01 | 20:00 | Nacional | 0–0 | Boyacá Patriot | 15,000 | Estadio Atanasio Girardot | Carlos Ortega | Match Report | |
| Regular season | 3 | Sat | 2018-08-04 | 16:00 | Huila | 2–2 | Rionegro | 200 | Estadio Guillermo Plazas Alcid | Heider Castro | Match Report | |
| Regular season | 3 | Sat | 2018-08-04 | 18:00 | Envigado | 0–1 | Junior | 3,500 | Estadio Polideportivo Sur | Luis Sánchez | Match Report | |
| Regular season | 3 | Sat | 2018-08-04 | 18:00 | CA Bucaramanga | 0–2 | La Equidad | 7,000 | Estadio Alfonso López | Ferney Trujillo | Match Report | |
| Regular season | 3 | Sun | 2018-08-05 | 15:15 | Boyacá Chicó | 1–1 | AD Cali | 500 | Estadio de la Independencia | Bismark Santiago | Match Report | |
| Regular season | 3 | Sun | 2018-08-05 | 17:15 | CD América | 0–0 | Santa Fe | 3,500 | Estadio Olímpico Pascual Guerrero | Diego Escalante | Match Report | |
| Regular season | 3 | Sun | 2018-08-05 | 17:30 | Pasto | 0–0 | Once Caldas | 3,500 | Estadio Departamental Libertad | Andrés Rojas | Match Report | |
| Regular season | 3 | Sat | 2018-08-04 | 20:00 | Millonarios | 0–1 | Independiente | 12,570 | Estadio Nemesio Camacho El Campín | Gustavo Murillo | Match Report | |
| Regular season | 3 | Sun | 2018-08-05 | 19:30 | Alianza | 4–2 | Tolima | 6,000 | Estadio Daniel Villa Zapata | Carlos Mario Herrera | Match Report | |
| Regular season | 3 | Mon | 2018-08-06 | 19:45 | Jaguares | 2–0 | Leones FC | 1,000 | Estadio de Fútbol Jaraguay de Montería | Carlos Betancur | Match Report | |
| Regular season | 4 | Sat | 2018-08-11 | 14:00 | Leones FC | 0–1 | CA Bucaramanga | 1,500 | Estadio Metropolitano de Itagüí | Gustavo Murillo | Match Report | |
| Regular season | 4 | Sat | 2018-08-11 | 16:00 | Rionegro | 1–0 | Boyacá Chicó | 3,500 | Estadio Alberto Grisales | Nolberto Ararat | Match Report | |
| Regular season | 4 | Sat | 2018-08-11 | 18:00 | Boyacá Patriot | 0–0 | CD América | 7,000 | Estadio de la Independencia | Óscar Masegosa | Match Report | |
| Regular season | 4 | Sat | 2018-08-11 | 18:00 | Santa Fe | 4–0 | Alianza | 7,548 | Estadio Nemesio Camacho El Campín | Jorge Guzmán | Match Report | |
| Regular season | 4 | Fri | 2018-08-10 | 19:45 | Tolima | 2–2 | Jaguares | 2,000 | Estadio Manuel Murillo Toro | Lisandro Castillo | Match Report | |
| Regular season | 4 | Sun | 2018-08-12 | 15:15 | La Equidad | 1–0 | Pasto | 946 | Estadio Metropolitano de Techo | Jorge Duarte | Match Report | |
| Regular season | 4 | Sun | 2018-08-12 | 17:30 | Once Caldas | 3–1 | Envigado | 6,153 | Estadio Palogrande | Carlos Mario Herrera | Match Report | |
| Regular season | 4 | Sat | 2018-08-11 | 20:00 | AD Cali | 3–2 | Independiente | 20,000 | Estadio Deportivo Cali | Ricardo García | Match Report | |
| Regular season | 4 | Sun | 2018-08-12 | 19:30 | Nacional | 1–1 | Millonarios | 21,433 | Estadio Atanasio Girardot | John J. Ospina | Match Report | |
| Regular season | 4 | Sun | 2018-08-12 | 19:30 | Junior | 3–0 | Huila | 6,318 | Estadio Metropolitano Roberto Meléndez | Nicolás Rodríguez | Match Report | |
| Regular season | 5 | Sat | 2018-08-18 | 15:15 | Alianza | 3–2 | Boyacá Patriot | 2,000 | Estadio Daniel Villa Zapata | Diego Escalante | Match Report | |
| Regular season | 5 | Sat | 2018-08-18 | 17:30 | CD América | 0–2 | Nacional | 8,500 | Estadio Olímpico Pascual Guerrero | Nicolás Gallo | Match Report | |
| Regular season | 5 | Sat | 2018-08-18 | 18:00 | Boyacá Chicó | 2–1 | Junior | 2,000 | Estadio de la Independencia | Jorge Guzmán | Match Report | |
| Regular season | 5 | Sun | 2018-08-19 | 16:00 | Independiente | 1–0 | Rionegro | 13,042 | Estadio Atanasio Girardot | John J. Ospina | Match Report | |
| Regular season | 5 | Sun | 2018-08-19 | 17:15 | Millonarios | 0–0 | AD Cali | 16,649 | Estadio Nemesio Camacho El Campín | Wilmar Roldán | Match Report | |
| Regular season | 5 | Sun | 2018-08-19 | 18:00 | Huila | 1–2 | Once Caldas | 300 | Estadio Guillermo Plazas Alcid | Bismark Santiago | Match Report | |
| Regular season | 5 | Sat | 2018-08-18 | 19:45 | CA Bucaramanga | 0–2 | Tolima | 2,000 | Estadio Alfonso López | Carlos Betancourt | Match Report | |
| Regular season | 5 | Mon | 2018-08-20 | 17:30 | Envigado | 0–1 | La Equidad | 1,500 | Estadio Polideportivo Sur | Luis Trujillo | Match Report | |
| Regular season | 5 | Sun | 2018-08-19 | 20:00 | Jaguares | 0–0 | Santa Fe | 3,000 | Estadio de Fútbol Jaraguay de Montería | Luis Sánchez | Match Report | |
| Regular season | 5 | Tue | 2018-08-21 | 19:30 | Pasto | 2–1 | Leones FC | 1,500 | Estadio Departamental Libertad | Carlos Ortega | Match Report | |
| Regular season | 6 | Fri | 2018-08-24 | 18:00 | La Equidad | 1–0 | Huila | 3,000 | Estadio Metropolitano de Techo | Gustavo Murillo | Match Report | |
| Regular season | 6 | Sat | 2018-08-25 | 14:00 | Leones FC | 1–1 | Envigado | 2,000 | Estadio Metropolitano de Itagüí | Óscar Masegosa | Match Report | |
| Regular season | 6 | Sat | 2018-08-25 | 16:00 | Santa Fe | 1–1 | CA Bucaramanga | 8,970 | Estadio Nemesio Camacho El Campín | Carlos Ortega | Match Report | |
| Regular season | 6 | Sat | 2018-08-25 | 16:00 | Rionegro | 2–0 | AD Cali | 4,500 | Estadio Alberto Grisales | Andrés Rojas | Match Report | |
| Regular season | 6 | Sat | 2018-08-25 | 18:00 | CD América | 0–2 | Millonarios | 5,580 | Estadio Olímpico Pascual Guerrero | Jorge Guzmán | Match Report | |
| Regular season | 6 | Sat | 2018-08-25 | 18:00 | Once Caldas | 3–1 | Boyacá Chicó | 7,091 | Estadio Palogrande | Heider Castro | Match Report | |
| Regular season | 6 | Fri | 2018-08-24 | 20:00 | Nacional | 3–2 | Alianza | 13,766 | Estadio Atanasio Girardot | Nicolás Rodríguez | Match Report | |
| Regular season | 6 | Sat | 2018-08-25 | 20:00 | Junior | 2–1 | Independiente | 10,780 | Estadio Metropolitano Roberto Meléndez | Nicolás Gallo | Match Report | |
| Regular season | 6 | Mon | 2018-08-27 | 18:00 | Boyacá Patriot | 4–0 | Jaguares | 1,000 | Estadio de la Independencia | Jorge Tabares | Match Report | |
| Regular season | 6 | Mon | 2018-08-27 | 20:00 | Tolima | 1–0 | Pasto | 3,000 | Estadio Manuel Murillo Toro | Ferney Trujillo | Match Report | |
| Regular season | 7 | Sat | 2018-09-01 | 14:00 | Boyacá Chicó | 0–1 | La Equidad | 500 | Estadio de la Independencia | Bismark Santiago | Match Report | |
| Regular season | 7 | Sat | 2018-09-01 | 16:00 | Huila | 2–3 | Leones FC | 200 | Estadio Guillermo Plazas Alcid | John J. Ospina | Match Report | |
| Regular season | 7 | Sat | 2018-09-01 | 18:00 | Envigado | 1–3 | Tolima | 1,000 | Estadio Polideportivo Sur | Nolberto Ararat | Match Report | |
| Regular season | 7 | Sat | 2018-09-01 | 18:00 | Millonarios | 1–1 | Rionegro | 11,376 | Estadio Nemesio Camacho El Campín | Nicolás Gallo | Match Report | |
| Regular season | 7 | Sun | 2018-09-02 | 14:00 | Pasto | 1–1 | Santa Fe | 4,500 | Estadio Departamental Libertad | Luis Trujillo | Match Report | |
| Regular season | 7 | Sun | 2018-09-02 | 16:00 | CA Bucaramanga | 2–1 | Boyacá Patriot | 5,000 | Estadio Alfonso López | Luis Sánchez | Match Report | |
| Regular season | 7 | Sun | 2018-09-02 | 17:15 | Independiente | 2–2 | Once Caldas | 15,384 | Estadio Atanasio Girardot | Gustavo Murillo | Match Report | |
| Regular season | 7 | Sun | 2018-09-02 | 18:00 | Jaguares | 1–1 | Nacional | 8,000 | Estadio de Fútbol Jaraguay de Montería | Carlos Mario Herrera | Match Report | |
| Regular season | 7 | Sat | 2018-09-01 | 20:00 | Alianza | 2–2 | CD América | 7,000 | Estadio Daniel Villa Zapata | Jhon Hinestroza | Match Report | |
| Regular season | 7 | Sun | 2018-09-02 | 20:00 | AD Cali | 1–0 | Junior | 6,000 | Estadio Deportivo Cali | Diego Escalante | Match Report | |
| Regular season | 8 | Tue | 2018-09-04 | 16:00 | Leones FC | 1–2 | Boyacá Chicó | 500 | Estadio Metropolitano de Itagüí | Éder Vergara | Match Report | |
| Regular season | 8 | Tue | 2018-09-04 | 18:00 | Tolima | 2–0 | Huila | 2,000 | Estadio Manuel Murillo Toro | Edilson Ariza | Match Report | |
| Regular season | 8 | Wed | 2018-09-05 | 16:00 | Boyacá Patriot | 1–1 | Pasto | 1,000 | Estadio de la Independencia | Nolberto Ararat | Match Report | |
| Regular season | 8 | Wed | 2018-09-05 | 18:00 | CD América | 2–1 | Jaguares | 200 | Estadio Olímpico Pascual Guerrero | Nicolás Rodríguez | Match Report | |
| Regular season | 8 | Wed | 2018-09-05 | 18:00 | Santa Fe | 3–1 | Envigado | 8,970 | Estadio Nemesio Camacho El Campín | Ferney Trujillo | Match Report | |
| Regular season | 8 | Tue | 2018-09-04 | 20:00 | Alianza | 3–2 | Millonarios | 4,000 | Estadio Daniel Villa Zapata | Bismark Santiago | Match Report | |
| Regular season | 8 | Thu | 2018-09-06 | 18:00 | Once Caldas | 3–1 | AD Cali | 8,992 | Estadio Palogrande | Jhon Hinestroza | Match Report | |
| Regular season | 8 | Thu | 2018-09-06 | 18:00 | Junior | 2–0 | Rionegro | 2,949 | Estadio Metropolitano Roberto Meléndez | Ricardo García | Match Report | |
| Regular season | 8 | Wed | 2018-09-05 | 20:00 | Nacional | 2–3 | CA Bucaramanga | 10,322 | Estadio Atanasio Girardot | Jorge Guzmán | Match Report | |
| Regular season | 8 | Thu | 2018-09-06 | 20:00 | La Equidad | 1–1 | Independiente | 2,000 | Estadio Metropolitano de Techo | Carlos Mario Herrera | Match Report | |
| Regular season | 9 | Sat | 2018-09-08 | 15:15 | Jaguares | 1–0 | Alianza | 2,000 | Estadio de Fútbol Jaraguay de Montería | Gustavo Murillo | Match Report | |
| Regular season | 9 | Sat | 2018-09-08 | 17:30 | Boyacá Chicó | 2–1 | Tolima | 500 | Estadio de la Independencia | Carlos Ortega | Match Report | |
| Regular season | 9 | Sat | 2018-09-08 | 18:00 | CA Bucaramanga | 2–3 | CD América | 21,000 | Estadio Alfonso López | Bismark Santiago | Match Report | |
| Regular season | 9 | Sun | 2018-09-09 | 13:15 | Envigado | 2–1 | Boyacá Patriot | 1,500 | Estadio Polideportivo Sur | Lisandro Castillo | Match Report | |
| Regular season | 9 | Sun | 2018-09-09 | 15:15 | Independiente | 1–1 | Leones FC | 11,263 | Estadio Atanasio Girardot | Jorge Duarte | Match Report | |
| Regular season | 9 | Sun | 2018-09-09 | 17:15 | AD Cali | 3–0 | La Equidad | 5,000 | Estadio Deportivo Cali | Edilson Ariza | Match Report | |
| Regular season | 9 | Sun | 2018-09-09 | 17:30 | Pasto | 0–2 | Nacional | 10,000 | Estadio Departamental Libertad | Heider Castro | Match Report | |
| Regular season | 9 | Sat | 2018-09-08 | 19:45 | Huila | 0–1 | Santa Fe | 500 | Estadio Guillermo Plazas Alcid | Óscar Masegosa | Match Report | |
| Regular season | 9 | Mon | 2018-09-10 | 18:00 | Rionegro | 1–0 | Once Caldas | 5,500 | Estadio Alberto Grisales | Nolberto Ararat | Match Report | |
| Regular season | 9 | Sun | 2018-09-09 | 19:30 | Millonarios | 1–1 | Junior | 12,316 | Estadio Nemesio Camacho El Campín | Luis Sánchez | Match Report | |
| Regular season | 10 | Sat | 2018-09-15 | 14:00 | Leones FC | 0–0 | AD Cali | 1,000 | Estadio Metropolitano de Itagüí | Carlos Ortega | Match Report | |
| Regular season | 10 | Sat | 2018-09-15 | 16:00 | Jaguares | 1–2 | Millonarios | 1,000 | Estadio de Fútbol Jaraguay de Montería | Carlos Betancourt | Match Report | |
| Regular season | 10 | Sat | 2018-09-15 | 18:00 | CD América | 3–1 | Pasto | 9,842 | Estadio Olímpico Pascual Guerrero | Lisandro Castillo | Match Report | |
| Regular season | 10 | Sat | 2018-09-15 | 18:00 | Santa Fe | 2–0 | Boyacá Chicó | 6,000 | Estadio Nemesio Camacho El Campín | Edilson Ariza | Match Report | |
| Regular season | 10 | Fri | 2018-09-14 | 20:00 | Boyacá Patriot | 1–0 | Huila | 2,500 | Estadio de la Independencia | Luis Trujillo | Match Report | |
| Regular season | 10 | Sun | 2018-09-16 | 16:00 | La Equidad | 0–2 | Rionegro | 559 | Estadio Metropolitano de Techo | Ferney Trujillo | Match Report | |
| Regular season | 10 | Sun | 2018-09-16 | 17:15 | Once Caldas | 1–0 | Junior | 9,950 | Estadio Palogrande | Jorge Duarte | Match Report | |
| Regular season | 10 | Sun | 2018-09-16 | 18:00 | Alianza | 1–2 | CA Bucaramanga | 6,000 | Estadio Daniel Villa Zapata | Óscar Masegosa | Match Report | |
| Regular season | 10 | Sat | 2018-09-15 | 20:00 | Tolima | 3–0 | Independiente | 9,000 | Estadio Manuel Murillo Toro | Heider Castro | Match Report | |
| Regular season | 10 | Sun | 2018-09-16 | 20:00 | Nacional | 3–1 | Envigado | 14,114 | Estadio Atanasio Girardot | Ricardo García | Match Report | |
| Regular season | 11 | Fri | 2018-09-21 | 18:00 | CA Bucaramanga | 2–1 | Jaguares | 3,000 | Estadio Alfonso López | Nolberto Ararat | Match Report | |
| Regular season | 11 | Sat | 2018-09-22 | 15:15 | Junior | 3–1 | La Equidad | 2,950 | Estadio Romelio Martínez | Wilmar Roldán | Match Report | |
| Regular season | 11 | Sat | 2018-09-22 | 17:30 | Rionegro | 2–1 | Leones FC | 5,000 | Estadio Alberto Grisales | Bismark Santiago | Match Report | |
| Regular season | 11 | Sat | 2018-09-22 | 18:00 | Independiente | 2–2 | Santa Fe | 11,861 | Estadio Atanasio Girardot | Nicolás Gallo | Match Report | |
| Regular season | 11 | Fri | 2018-09-21 | 20:00 | Boyacá Chicó | 1–1 | Boyacá Patriot | 2,500 | Estadio de la Independencia | Jhon Hinestroza | Match Report | |
| Regular season | 11 | Sun | 2018-09-23 | 17:15 | AD Cali | 0–1 | Tolima | 10,000 | Estadio Alfonso López | Andrés Rojas | Match Report | |
| Regular season | 11 | Sun | 2018-09-23 | 17:30 | Pasto | 2–1 | Alianza | 3,000 | Estadio Departamental Libertad | Carlos Ortega | Match Report | |
| Regular season | 11 | Sat | 2018-09-22 | 19:45 | Millonarios | 2–2 | Once Caldas | 10,813 | Estadio Nemesio Camacho El Campín | Diego Escalante | Match Report | |
| Regular season | 11 | Sun | 2018-09-23 | 19:30 | Huila | 1–0 | Nacional | 1,500 | Estadio Guillermo Plazas Alcid | Carlos Betancourt | Match Report | |
| Regular season | 11 | Mon | 2018-09-24 | 19:45 | Envigado | 1–1 | CD América | 3,500 | Estadio Polideportivo Sur | Éder Vergara | Match Report | |
| Regular season | 12 | Sat | 2018-09-29 | 14:00 | Leones FC | 2–2 | Junior | 500 | Estadio Metropolitano de Itagüí | Carlos Betancourt | Match Report | |
| Regular season | 12 | Sat | 2018-09-29 | 16:00 | Tolima | 1–1 | Rionegro | 3,000 | Estadio Manuel Murillo Toro | Nicolás Rodríguez | Match Report | |
| Regular season | 12 | Sat | 2018-09-29 | 18:00 | Santa Fe | 0–2 | AD Cali | 9,687 | Estadio Nemesio Camacho El Campín | Wilmar Roldán | Match Report | |
| Regular season | 12 | Sat | 2018-09-29 | 18:00 | Alianza | 1–2 | Envigado | 2,000 | Estadio Daniel Villa Zapata | Carlos Mario Herrera | Match Report | |
| Regular season | 12 | Fri | 2018-09-28 | 20:00 | Boyacá Patriot | 0–3 | Independiente | 500 | Estadio de la Independencia | Ferney Trujillo | Match Report | |
| Regular season | 12 | Sun | 2018-09-30 | 15:15 | Jaguares | 0–2 | Pasto | 1,000 | Estadio de Fútbol Jaraguay de Montería | Andrés Rojas | Match Report | |
| Regular season | 12 | Sun | 2018-09-30 | 17:15 | CD América | 0–0 | Huila | 16,800 | Estadio Olímpico Pascual Guerrero | Heider Castro | Match Report | |
| Regular season | 12 | Sun | 2018-09-30 | 17:30 | Nacional | 3–2 | Boyacá Chicó | 13,955 | Estadio Atanasio Girardot | Nicolás Gallo | Match Report | |
| Regular season | 12 | Sat | 2018-09-29 | 20:00 | CA Bucaramanga | 2–1 | Millonarios | 22,000 | Estadio Alfonso López | Jhon Hinestroza | Match Report | |
| Regular season | 12 | Sun | 2018-09-30 | 19:30 | La Equidad | 1–1 | Once Caldas | 1,722 | Estadio Metropolitano de Techo | Ricardo García | Match Report | |
| Regular season | 13 | Sat | 2018-10-06 | 15:15 | Huila | 2–1 | Alianza | 300 | Estadio Guillermo Plazas Alcid | Lisandro Castillo | Match Report | |
| Regular season | 13 | Sat | 2018-10-06 | 17:30 | Independiente | 2–1 | Nacional | 29,929 | Estadio Atanasio Girardot | Andrés Rojas | Match Report | |
| Regular season | 13 | Sat | 2018-10-06 | 18:00 | AD Cali | 0–2 | Boyacá Patriot | 6,000 | Estadio Deportivo Cali | Nicolás Rodríguez | Match Report | |
| Regular season | 13 | Sun | 2018-10-07 | 17:15 | Boyacá Chicó | 2–1 | CD América | 3,500 | Estadio de la Independencia | Carlos Mario Herrera | Match Report | |
| Regular season | 13 | Sun | 2018-10-07 | 17:15 | Envigado | 1–0 | Jaguares | 3,000 | Estadio Polideportivo Sur | Ferney Trujillo | Match Report | |
| Regular season | 13 | Sat | 2018-10-06 | 19:45 | Rionegro | 0–3 | Santa Fe | 6,000 | Estadio Alberto Grisales | Edilson Ariza | Match Report | |
| Regular season | 13 | Mon | 2018-10-08 | 18:00 | Once Caldas | 0–0 | Leones FC | 6,500 | Estadio Palogrande | Luis Trujillo | Match Report | |
| Regular season | 13 | Sun | 2018-10-07 | 19:30 | Pasto | 0–1 | CA Bucaramanga | 2,000 | Estadio Departamental Libertad | Carlos Betancourt | Match Report | |
| Regular season | 13 | Mon | 2018-10-08 | 20:00 | Millonarios | 2–3 | La Equidad | 7,695 | Estadio Nemesio Camacho El Campín | Bismark Santiago | Match Report | |
| Regular season | 13 | Tue | 2018-10-09 | 19:30 | Junior | 4–3 | Tolima | 9,721 | Estadio Metropolitano Roberto Meléndez | Jhon Hinestroza | Match Report | |
| Regular season | 14 | Fri | 2018-10-12 | 16:00 | Boyacá Patriot | 0–1 | Rionegro | 1,000 | Estadio de la Independencia | Andrés Rojas | Match Report | |
| Regular season | 14 | Sat | 2018-10-13 | 15:15 | Jaguares | 0–0 | Huila | 1,200 | Estadio de Fútbol Jaraguay de Montería | Edilson Ariza | Match Report | |
| Regular season | 14 | Sat | 2018-10-13 | 17:30 | Alianza | 1–0 | Boyacá Chicó | 3,500 | Estadio Daniel Villa Zapata | Wilmar Roldán | Match Report | |
| Regular season | 14 | Sun | 2018-10-14 | 15:15 | Leones FC | 0–1 | La Equidad | 3,000 | Estadio Metropolitano de Itagüí | Éder Vergara | Match Report | |
| Regular season | 14 | Sun | 2018-10-14 | 17:15 | Nacional | 0–0 | AD Cali | 19,140 | Estadio Atanasio Girardot | Carlos Mario Herrera | Match Report | |
| Regular season | 14 | Sun | 2018-10-14 | 17:30 | CA Bucaramanga | 2–1 | Envigado | 10,000 | Estadio Alfonso López | Heider Castro | Match Report | |
| Regular season | 14 | Sat | 2018-10-13 | 19:45 | Santa Fe | 2–2 | Junior | 10,000 | Estadio Nemesio Camacho El Campín | Jorge Guzmán | Match Report | |
| Regular season | 14 | Mon | 2018-10-15 | 18:00 | Pasto | 0–1 | Millonarios | 3,000 | Estadio Departamental Libertad | Gustavo Murillo | Match Report | |
| Regular season | 14 | Sun | 2018-10-14 | 19:30 | CD América | 1–2 | Independiente | 10,000 | Estadio Olímpico Pascual Guerrero | Bismark Santiago | Match Report | |
| Regular season | 15 | Wed | 2018-10-17 | 16:00 | Huila | 0–2 | CA Bucaramanga | 500 | Estadio Guillermo Plazas Alcid | Luis Trujillo | Match Report | |
| Regular season | 15 | Wed | 2018-10-17 | 18:00 | Junior | 4–0 | Boyacá Patriot | 5,328 | Estadio Romelio Martínez | Óscar Masegosa | Match Report | |
| Regular season | 15 | Wed | 2018-10-17 | 18:00 | La Equidad | 0–1 | Tolima | 1,849 | Estadio Metropolitano de Techo | Wilmar Roldán | Match Report | |
| Regular season | 15 | Thu | 2018-10-18 | 16:00 | Envigado | 1–0 | Pasto | 1,500 | Estadio Polideportivo Sur | Nicolás Rodríguez | Match Report | |
| Regular season | 15 | Thu | 2018-10-18 | 18:00 | AD Cali | 1–0 | CD América | 15,000 | Estadio Deportivo Cali | Jhon Hinestroza | Match Report | |
| Regular season | 15 | Wed | 2018-10-17 | 20:00 | Once Caldas | 1–0 | Santa Fe | 10,900 | Estadio Palogrande | Carlos Mario Herrera | Match Report | |
| Regular season | 15 | Wed | 2018-10-17 | 20:00 | Boyacá Chicó | 1–0 | Jaguares | 270 | Estadio de la Independencia | Jhon Hinestroza | Match Report | |
| Regular season | 15 | Wed | 2018-10-17 | 20:00 | Independiente | 2–0 | Alianza | 11,710 | Estadio Atanasio Girardot | Luis Sánchez | Match Report | |
| Regular season | 15 | Thu | 2018-10-18 | 20:00 | Rionegro | 1–3 | Nacional | 3,000 | Estadio Alberto Grisales | Ricardo García | Match Report | |
| Regular season | 15 | Thu | 2018-10-18 | 20:00 | Millonarios | 1–0 | Leones FC | 12,000 | Estadio Nemesio Camacho El Campín | Ferney Trujillo | Match Report | |
| Regular season | 16 | Sat | 2018-10-20 | 15:15 | Jaguares | 0–2 | Independiente | 3,000 | Estadio de Fútbol Jaraguay de Montería | Heider Castro | Match Report | |
| Regular season | 16 | Sat | 2018-10-20 | 17:30 | CA Bucaramanga | 3–0 | Boyacá Chicó | 10,000 | Estadio Alfonso López | Gustavo Murillo | Match Report | |
| Regular season | 16 | Sat | 2018-10-20 | 18:00 | Santa Fe | 0–1 | La Equidad | 11,124 | Estadio Nemesio Camacho El Campín | Andrés Rojas | Match Report | |
| Regular season | 16 | Sun | 2018-10-21 | 14:00 | Tolima | 3–2 | Leones FC | 2,500 | Estadio Manuel Murillo Toro | Luis Sánchez | Match Report | |
| Regular season | 16 | Sun | 2018-10-21 | 16:00 | CD América | 2–1 | Rionegro | 2,300 | Estadio Olímpico Pascual Guerrero | Carlos Ortega | Match Report | |
| Regular season | 16 | Sun | 2018-10-21 | 17:15 | Nacional | 1–0 | Junior | 22,000 | Estadio Atanasio Girardot | Jhon Hinestroza | Match Report | |
| Regular season | 16 | Sun | 2018-10-21 | 18:00 | Alianza | 2–0 | AD Cali | 2,000 | Estadio Daniel Villa Zapata | Ferney Trujillo | Match Report | |
| Regular season | 16 | Sat | 2018-10-20 | 19:45 | Boyacá Patriot | 1–0 | Once Caldas | 1,000 | Estadio de la Independencia | Edilson Ariza | Match Report | |
| Regular season | 16 | Mon | 2018-10-22 | 18:00 | Pasto | 0–0 | Huila | 1,000 | Estadio Departamental Libertad | Wilmar Roldán | Match Report | |
| Regular season | 16 | Sun | 2018-10-21 | 20:00 | Envigado | 1–2 | Millonarios | 1,000 | Estadio Polideportivo Sur | Jorge Guzmán | Match Report | |
| Regular season | 17 | Fri | 2018-10-26 | 18:00 | Boyacá Chicó | 1–1 | Pasto | 500 | Estadio de la Independencia | Éder Vergara | Match Report | |
| Regular season | 17 | Sat | 2018-10-27 | 14:00 | Leones FC | 0–2 | Santa Fe | 3,500 | Estadio Metropolitano de Itagüí | Nolberto Ararat | Match Report | |
| Regular season | 17 | Sat | 2018-10-27 | 16:00 | AD Cali | 4–0 | Jaguares | 1,200 | Estadio Deportivo Cali | Edilson Ariza | Match Report | |
| Regular season | 17 | Sat | 2018-10-27 | 18:00 | Rionegro | 1–0 | Alianza | 6,000 | Estadio Alberto Grisales | Carlos Mario Herrera | Match Report | |
| Regular season | 17 | Sat | 2018-10-27 | 18:00 | Millonarios | 1–1 | Tolima | 15,880 | Estadio Nemesio Camacho El Campín | Wilmar Roldán | Match Report | |
| Regular season | 17 | Sun | 2018-10-28 | 14:00 | La Equidad | 4–0 | Boyacá Patriot | 780 | Estadio Metropolitano de Techo | Jorge Tabares | Match Report | |
| Regular season | 17 | Sun | 2018-10-28 | 17:15 | Junior | 0–0 | CD América | 17,627 | Estadio Metropolitano Roberto Meléndez | Andrés Rojas | Match Report | |
| Regular season | 17 | Sun | 2018-10-28 | 18:00 | Huila | 2–1 | Envigado | 1,500 | Estadio Guillermo Plazas Alcid | Gustavo Murillo | Match Report | |
| Regular season | 17 | Sat | 2018-10-27 | 20:00 | Once Caldas | 2–0 | Nacional | 1,549 | Estadio Palogrande | Luis Sánchez | Match Report | |
| Regular season | 17 | Sun | 2018-10-28 | 20:00 | Independiente | 2–0 | CA Bucaramanga | 23,714 | Estadio Atanasio Girardot | Carlos Ortega | Match Report | |
| Regular season | 18 | Sat | 2018-11-03 | 15:15 | Santa Fe | 3–0 | Tolima | 8,728 | Estadio Nemesio Camacho El Campín | Gustavo Murillo | Match Report | |
| Regular season | 18 | Sat | 2018-11-03 | 17:30 | Envigado | 1–0 | Boyacá Chicó | 500 | Estadio Polideportivo Sur | Jonathan Ortíz | Match Report | |
| Regular season | 18 | Sat | 2018-11-03 | 18:00 | CA Bucaramanga | 1–0 | AD Cali | 20,000 | Estadio Alfonso López | Wilmar Roldán | Match Report | |
| Regular season | 18 | Sun | 2018-11-04 | 14:00 | Boyacá Patriot | 2–1 | Leones FC | 130 | Estadio de la Independencia | Lisandro Castillo | Match Report | |
| Regular season | 18 | Sun | 2018-11-04 | 16:00 | Jaguares | 2–2 | Rionegro | 1,000 | Estadio de Fútbol Jaraguay de Montería | Ferney Trujillo | Match Report | |
| Regular season | 18 | Sun | 2018-11-04 | 18:00 | CD América | 1–1 | Once Caldas | 3,604 | Estadio Olímpico Pascual Guerrero | Heider Castro | Match Report | |
| Regular season | 18 | Sat | 2018-11-03 | 19:15 | Huila | 1–0 | Millonarios | 1,500 | Estadio Guillermo Plazas Alcid | Nicolás Gallo | Match Report | |
| Regular season | 18 | Mon | 2018-11-05 | 18:00 | Nacional | 0–0 | La Equidad | 21,593 | Estadio Atanasio Girardot | Edilson Ariza | Match Report | |
| Regular season | 18 | Sun | 2018-11-04 | 20:00 | Pasto | 1–1 | Independiente | 2,000 | Estadio Departamental Libertad | Jorge Guzmán | Match Report | |
| Regular season | 18 | Mon | 2018-11-05 | 19:30 | Alianza | 0–3 | Junior | 7,000 | Estadio Daniel Villa Zapata | Nolberto Ararat | Match Report | |
| Regular season | 14 | Wed | 2018-11-07 | 19:30 | Tolima | 3–0 | Once Caldas | 5,000 | Estadio Manuel Murillo Toro | Carlos Betancourt | Match Report | |
| Regular season | 19 | Sat | 2018-11-10 | 15:15 | Tolima | 2–1 | Boyacá Patriot | 2,000 | Estadio Manuel Murillo Toro | Luis Trujillo | Match Report | |
| Regular season | 19 | Sat | 2018-11-10 | 17:30 | Once Caldas | 1–0 | Alianza | 5,727 | Estadio Palogrande | Nicolás Rodríguez | Match Report | |
| Regular season | 19 | Sat | 2018-11-10 | 18:00 | La Equidad | 1–2 | CD América | 5,000 | Estadio Metropolitano de Techo | Éder Vergara | Match Report | |
| Regular season | 19 | Fri | 2018-11-09 | 19:45 | Boyacá Chicó | 2–2 | Huila | 1,000 | Estadio de la Independencia | Diego Escalante | Match Report | |
| Regular season | 19 | Sun | 2018-11-11 | 17:30 | AD Cali | 1–0 | Pasto | 10,764 | Estadio Deportivo Cali | Carlos Mario Herrera | Match Report | |
| Regular season | 19 | Sun | 2018-11-11 | 17:30 | Leones FC | 2–2 | Nacional | 4,000 | Estadio Metropolitano de Itagüí | Carlos Ortega | Match Report | |
| Regular season | 19 | Sun | 2018-11-11 | 17:30 | Millonarios | 0–3 | Santa Fe | 10,764 | Estadio Nemesio Camacho El Campín | Bismark Santiago | Match Report | |
| Regular season | 19 | Sun | 2018-11-11 | 17:30 | Rionegro | 1–0 | CA Bucaramanga | 6,000 | Estadio Alberto Grisales | Nicolás Gallo | Match Report | |
| Regular season | 19 | Sat | 2018-11-10 | 19:45 | Independiente | 2–2 | Envigado | 15,394 | Estadio Atanasio Girardot | Nolberto Ararat | Match Report | |
| Regular season | 19 | Sun | 2018-11-11 | 19:45 | Junior | 1–2 | Jaguares | 6,000 | Estadio Metropolitano Roberto Meléndez | Jorge Tabares | Match Report | |
| Quarter-finals | Wed | 2018-11-14 | 20:00 | Santa Fe | 1–2 | Tolima | 22,000 | Estadio Nemesio Camacho El Campín | Nicolás Gallo | Match Report | Leg 1 of 2 | |
| Quarter-finals | Wed | 2018-11-14 | 20:00 | Independiente | 3–0 | CA Bucaramanga | 22,000 | Estadio Atanasio Girardot | Luis Sánchez | Match Report | Leg 1 of 2 | |
| Quarter-finals | Thu | 2018-11-15 | 19:00 | Rionegro | 1–0 | Once Caldas | 9,419 | Estadio Alberto Grisales | Carlos Mario Herrera | Match Report | Leg 1 of 2 | |
| Quarter-finals | Thu | 2018-11-15 | 20:00 | Junior | 1–0 | La Equidad | 7,796 | Estadio Metropolitano Roberto Meléndez | Wilmar Roldán | Match Report | Leg 1 of 2 | |
| Quarter-finals | Sat | 2018-11-17 | 18:00 | CA Bucaramanga | 2–0 | Independiente | 20,000 | Estadio Alfonso López | Gustavo Murillo | Match Report | Leg 2 of 2; Independiente won | |
| Quarter-finals | Sun | 2018-11-18 | 17:15 | Once Caldas | 1–1 | Rionegro | 10,000 | Estadio Palogrande | Luis Sánchez | Match Report | Leg 2 of 2; Rionegro won | |
| Quarter-finals | Sat | 2018-11-17 | 20:00 | Tolima | (4) 0–1 (3) | Santa Fe | 20,000 | Estadio Manuel Murillo Toro | Bismark Santiago | Match Report | Leg 2 of 2; Tolima won; Tolima won on penalty kicks following extra time | |
| Quarter-finals | Sun | 2018-11-18 | 19:30 | La Equidad | 0–0 | Junior | 5,000 | Estadio Metropolitano de Techo | Carlos Betancourt | Match Report | Leg 2 of 2; Junior won | |
| Semi-finals | Wed | 2018-11-21 | 19:00 | Independiente | 2–2 | Tolima | 22,876 | Estadio Atanasio Girardot | Carlos Betancourt | Match Report | Leg 1 of 2 | |
| Semi-finals | Thu | 2018-11-22 | 19:45 | Rionegro | 2–3 | Junior | 5,000 | Estadio Alberto Grisales | Andrés Rojas | Match Report | Leg 1 of 2 | |
| Semi-finals | Sun | 2018-11-25 | 17:15 | Junior | 1–1 | Rionegro | 18,965 | Estadio Metropolitano Roberto Meléndez | Carlos Mario Herrera | Match Report | Leg 2 of 2; Junior won | |
| Semi-finals | Sun | 2018-11-25 | 19:30 | Tolima | 0–2 | Independiente | 25,000 | Estadio Manuel Murillo Toro | Luis Sánchez | Match Report | Leg 2 of 2; Independiente won | |
| Finals | Sat | 2018-12-08 | 19:00 | Junior | 4–1 | Independiente | 40,072 | Estadio Metropolitano Roberto Meléndez | Jhon Hinestroza | Match Report | Leg 1 of 2 | |
| Finals | Sun | 2018-12-16 | 16:30 | Independiente | 3–1 | Junior | 43,445 | Estadio Atanasio Girardot | Carlos Betancourt | Match Report | Leg 2 of 2; Junior won |
| Wk | Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Sat | 2018-02-03 | 16:00 | Rionegro | 0–0 | Pasto | 4,000 | Estadio Alberto Grisales | Carlos Ortega | Match Report | |
| 1 | Sat | 2018-02-03 | 18:00 | Leones FC | 1–2 | CD América | 5,000 | Estadio Metropolitano de Itagüí | Ferney Trujillo | Match Report | |
| 1 | Sat | 2018-02-03 | 18:00 | Once Caldas | 2–0 | Jaguares | 7,000 | Estadio Palogrande | Leonard Mosquera | Match Report | |
| 1 | Fri | 2018-02-02 | 19:45 | Independiente | 3–0 | Huila | 14,596 | Estadio Atanasio Girardot | Heider Castro | Match Report | |
| 1 | Sun | 2018-02-04 | 15:15 | Junior | 1–0 | CA Bucaramanga | 12,855 | Estadio Metropolitano Roberto Meléndez | Óscar Masegosa | Match Report | |
| 1 | Sun | 2018-02-04 | 17:15 | Tolima | 0–1 | Nacional | 13,000 | Estadio Manuel Murillo Toro | Éder Vergara | Match Report | |
| 1 | Sun | 2018-02-04 | 17:30 | Santa Fe | 0–2 | Boyacá Patriot | 9,093 | Estadio Nemesio Camacho El Campín | John J. Ospina | Match Report | |
| 1 | Sat | 2018-02-03 | 20:00 | AD Cali | 0–0 | Envigado | 6,000 | Estadio Deportivo Cali | Lisandro Castillo | Match Report | |
| 1 | Sun | 2018-02-04 | 19:30 | Boyacá Chicó | 1–1 | Millonarios | 10,000 | Estadio de la Independencia | Ervin Otero | Match Report | |
| 1 | Mon | 2018-02-05 | 19:45 | La Equidad | 0–0 | Alianza | 1,000 | Estadio Metropolitano de Techo | Luis Sánchez | Match Report | |
| 2 | Sat | 2018-02-10 | 16:00 | Huila | 1–0 | AD Cali | 500 | Estadio Manuel Murillo Toro | Ricardo García | Match Report | |
| 2 | Sat | 2018-02-10 | 18:00 | Alianza | 1–0 | Leones FC | 2,000 | Estadio Daniel Villa Zapata | Nicolás Rodríguez | Match Report | |
| 2 | Sat | 2018-02-10 | 18:00 | CD América | 1–1 | Tolima | 14,247 | Estadio Olímpico Pascual Guerrero | Carlos Mario Herrera | Match Report | |
| 2 | Fri | 2018-02-09 | 19:45 | Envigado | 2–0 | Rionegro | 5,000 | Estadio Polideportivo Sur | Bismark Santiago | Match Report | |
| 2 | Sun | 2018-02-11 | 14:00 | Boyacá Chicó | 1–2 | Independiente | 2,000 | Estadio de la Independencia | Jhon Hinestroza | Match Report | |
| 2 | Sun | 2018-02-11 | 16:00 | Jaguares | 1–0 | La Equidad | 2,000 | Estadio Armando Tuirán Paternina | Jorge Guzmán | Match Report | |
| 2 | Sun | 2018-02-11 | 17:15 | Millonarios | 1–0 | Boyacá Patriot | 17,000 | Estadio Nemesio Camacho El Campín | Óscar Masegosa | Match Report | |
| 2 | Sun | 2018-02-11 | 18:00 | CA Bucaramanga | 1–2 | Once Caldas | 15,000 | Estadio Alfonso López | Never Manjarrés | Match Report | |
| 2 | Sat | 2018-02-10 | 20:00 | Nacional | 1–0 | Santa Fe | 23,749 | Estadio Atanasio Girardot | Luis Sánchez | Match Report | |
| 2 | Sun | 2018-02-11 | 20:00 | Pasto | 2–0 | Junior | 7,500 | Estadio Departamental Libertad | Andrés Rojas | Match Report | |
| 3 | Tue | 2018-02-13 | 18:00 | Rionegro | 0–0 | Huila | 600 | Estadio Alberto Grisales | Ferney Trujillo | Match Report | |
| 3 | Wed | 2018-02-14 | 16:00 | Leones FC | 0–0 | Jaguares | 500 | Estadio Metropolitano de Itagüí | Ervin Otero | Match Report | |
| 3 | Wed | 2018-02-14 | 18:00 | AD Cali | 4–0 | Boyacá Chicó | 3,500 | Estadio Deportivo Cali | John J. Ospina | Match Report | |
| 3 | Tue | 2018-02-13 | 20:00 | Tolima | 3–1 | Alianza | 2,800 | Estadio Manuel Murillo Toro | Diego Escalante | Match Report | |
| 3 | Thu | 2018-02-15 | 16:00 | La Equidad | 0–0 | CA Bucaramanga | 750 | Estadio Metropolitano de Techo | Wilmar Roldán | Match Report | |
| 3 | Thu | 2018-02-15 | 18:00 | Once Caldas | 3–0 | Pasto | 9,000 | Estadio Palogrande | Gustavo Murillo | Match Report | |
| 3 | Wed | 2018-02-14 | 20:00 | Independiente | 1–0 | Millonarios | 21,704 | Estadio Atanasio Girardot | Carlos Betancourt | Match Report | |
| 3 | Thu | 2018-02-15 | 20:00 | Boyacá Patriot | 3–1 | Nacional | 4,500 | Estadio de la Independencia | Carlos Ortega | Match Report | |
| 4 | Sat | 2018-02-17 | 16:00 | Jaguares | 2–0 | Tolima | 1,000 | Estadio de Fútbol Jaraguay de Montería | Jhon Hinestroza | Match Report | |
| 4 | Sat | 2018-02-17 | 18:00 | Independiente | 2–1 | AD Cali | 23,140 | Estadio Atanasio Girardot | Andrés Rojas | Match Report | |
| 4 | Sat | 2018-02-17 | 18:00 | Boyacá Chicó | 1–2 | Rionegro | 1,200 | Estadio de la Independencia | Éder Vergara | Match Report | |
| 4 | Sun | 2018-02-18 | 14:00 | Envigado | 1–0 | Once Caldas | 8,000 | Estadio Polideportivo Sur | Ricardo García | Match Report | |
| 4 | Sun | 2018-02-18 | 16:00 | CA Bucaramanga | 2–2 | Leones FC | 6,000 | Estadio Alfonso López | Heider Castro | Match Report | |
| 4 | Sun | 2018-02-18 | 17:15 | CD América | 2–0 | Boyacá Patriot | 15,000 | Estadio Olímpico Pascual Guerrero | Wilmar Roldán | Match Report | |
| 4 | Sun | 2018-02-18 | 18:00 | Huila | 1–0 | Junior | 500 | Estadio Manuel Murillo Toro | Carlos Betancourt | Match Report | |
| 4 | Sat | 2018-02-17 | 20:00 | Alianza | 2–1 | Santa Fe | 4,000 | Estadio Daniel Villa Zapata | Leonard Mosquera | Match Report | |
| 4 | Sun | 2018-02-18 | 20:00 | Millonarios | 1–1 | Nacional | 18,600 | Estadio Nemesio Camacho El Campín | Carlos Mario Herrera | Match Report | |
| 4 | Tue | 2018-02-20 | 19:45 | Pasto | 0–0 | La Equidad | 3,000 | Estadio Departamental Libertad | Bismark Santiago | Match Report | |
| 5 | Thu | 2018-02-22 | 19:05 | Nacional | 2–0 | CD América | 15,000 | Estadio Atanasio Girardot | Jhon Hinestroza | Match Report | |
| 5 | Sat | 2018-02-24 | 15:15 | Boyacá Patriot | 2–1 | Alianza | 450 | Estadio de la Independencia | Heider Castro | Match Report | |
| 5 | Sat | 2018-02-24 | 17:30 | Rionegro | 2–0 | Independiente | 6,300 | Estadio Alberto Grisales | John J. Ospina | Match Report | |
| 5 | Fri | 2018-02-23 | 19:45 | Leones FC | 2–1 | Pasto | 2,000 | Estadio Metropolitano de Itagüí | Luis Sánchez | Match Report | |
| 5 | Sun | 2018-02-25 | 14:00 | La Equidad | 1–0 | Envigado | 1,500 | Estadio Metropolitano de Techo | Ervin Otero | Match Report | |
| 5 | Sun | 2018-02-25 | 16:00 | Once Caldas | 1–0 | Huila | 10,000 | Estadio Palogrande | Diego Escalante | Match Report | |
| 5 | Sun | 2018-02-25 | 17:15 | Santa Fe | 4–0 | Jaguares | 10,000 | Estadio Nemesio Camacho El Campín | Carlos Betancourt | Match Report | |
| 5 | Sun | 2018-02-25 | 18:00 | Tolima | 0–1 | CA Bucaramanga | 1,500 | Estadio Manuel Murillo Toro | Nicolás Rodríguez | Match Report | |
| 5 | Sat | 2018-02-24 | 19:45 | AD Cali | 2–0 | Millonarios | 12,000 | Estadio Olímpico Pascual Guerrero | Gustavo Murillo | Match Report | |
| 5 | Sun | 2018-02-25 | 20:00 | Junior | 1–0 | Boyacá Chicó | 13,278 | Estadio Metropolitano Roberto Meléndez | Leonard Mosquera | Match Report | |
| 6 | Sat | 2018-03-03 | 14:00 | Envigado | 1–1 | Leones FC | 1,500 | Estadio Polideportivo Sur | Óscar Masegosa | Match Report | |
| 6 | Sat | 2018-03-03 | 16:00 | Jaguares | 0–0 | Boyacá Patriot | 2,000 | Estadio de Fútbol Jaraguay de Montería | Nicolás Gallo | Match Report | |
| 6 | Sat | 2018-03-03 | 18:00 | Huila | 3–1 | La Equidad | 200 | Estadio Manuel Murillo Toro | Leonard Mosquera | Match Report | |
| 6 | Sat | 2018-03-03 | 18:00 | Alianza | 1–2 | Nacional | 8,000 | Estadio Daniel Villa Zapata | Jorge Guzmán | Match Report | |
| 6 | Fri | 2018-03-02 | 19:45 | Boyacá Chicó | 2–2 | Once Caldas | 1,200 | Estadio de la Independencia | Bismark Santiago | Match Report | |
| 6 | Sun | 2018-03-04 | 15:15 | Millonarios | 3–1 | CD América | 18,483 | Estadio Nemesio Camacho El Campín | John J. Ospina | Match Report | |
| 6 | Sun | 2018-03-04 | 17:15 | Independiente | 1–2 | Junior | 22,343 | Estadio Atanasio Girardot | Ervin Otero | Match Report | |
| 6 | Sun | 2018-03-04 | 17:30 | Pasto | 1–1 | Tolima | 5,500 | Estadio Departamental Libertad | Wilmar Roldán | Match Report | |
| 6 | Sat | 2018-03-03 | 20:00 | AD Cali | 4–0 | Rionegro | 8,000 | Estadio Olímpico Pascual Guerrero | Jhon Hinestroza | Match Report | |
| 6 | Sun | 2018-03-04 | 19:30 | CA Bucaramanga | 1–0 | Santa Fe | 1,300 | Estadio Alfonso López | Gustavo Murillo | Match Report | |
| 7 | Tue | 2018-03-06 | 18:00 | Leones FC | 0–0 | Huila | 2,500 | Estadio Metropolitano de Itagüí | Never Manjarrés | Match Report | |
| 7 | Wed | 2018-03-07 | 18:00 | Once Caldas | 3–2 | Independiente | 13,000 | Estadio Palogrande | Luis Sánchez | Match Report | |
| 7 | Tue | 2018-03-06 | 20:00 | La Equidad | 4–0 | Boyacá Chicó | 1,000 | Estadio Metropolitano de Techo | Carlos Ortega | Match Report | |
| 7 | Thu | 2018-03-08 | 16:00 | Boyacá Patriot | 1–0 | CA Bucaramanga | 1,300 | Estadio de la Independencia | Carlos Betancourt | Match Report | |
| 7 | Thu | 2018-03-08 | 18:00 | Santa Fe | 1–0 | Pasto | 6,680 | Estadio Nemesio Camacho El Campín | Diego Escalante | Match Report | |
| 7 | Wed | 2018-03-07 | 20:00 | Nacional | 1–0 | Jaguares | 14,177 | Estadio Atanasio Girardot | Andrés Rojas | Match Report | |
| 7 | Thu | 2018-03-08 | 19:00 | Tolima | 2–1 | Envigado | 1,200 | Estadio Manuel Murillo Toro | Heider Castro | Match Report | |
| 7 | Thu | 2018-03-08 | 20:00 | Rionegro | 3–1 | Millonarios | 3,500 | Estadio Alberto Grisales | Ricardo García | Match Report | |
| 7 | Fri | 2018-03-09 | 20:00 | Junior | 2–1 | AD Cali | 15,729 | Estadio Metropolitano Roberto Meléndez | Nicolás Gallo | Match Report | |
| 8 | Tue | 2018-03-13 | 18:00 | Boyacá Chicó | 1–1 | Leones FC | 800 | Estadio de la Independencia | Carlos Mario Herrera | Match Report | |
| 8 | Wed | 2018-03-14 | 18:00 | Pasto | 1–1 | Boyacá Patriot | 2,500 | Estadio Departamental Libertad | Ferney Trujillo | Match Report | |
| 8 | Wed | 2018-03-14 | 18:00 | Envigado | 0–3 | Santa Fe | 2,000 | Estadio Polideportivo Sur | Luis Sánchez | Match Report | |
| 8 | Tue | 2018-03-13 | 20:00 | Independiente | 1–0 | La Equidad | 16,300 | Estadio Atanasio Girardot | Éder Vergara | Match Report | |
| 8 | Thu | 2018-03-15 | 18:00 | Rionegro | 0–0 | Junior | 3,000 | Estadio Alberto Grisales | Andrés Rojas | Match Report | |
| 8 | Wed | 2018-03-14 | 20:00 | AD Cali | 2–1 | Once Caldas | 8,000 | Estadio Olímpico Pascual Guerrero | Ervin Otero | Match Report | |
| 8 | Thu | 2018-03-15 | 20:00 | Jaguares | 1–0 | CD América | 12,000 | Estadio de Fútbol Jaraguay de Montería | Nicolás Rodríguez | Match Report | |
| 9 | Sat | 2018-03-17 | 17:30 | Tolima | 1–0 | Boyacá Chicó | 2,600 | Estadio Manuel Murillo Toro | Lisandro Castillo | Match Report | |
| 9 | Sat | 2018-03-17 | 18:00 | Santa Fe | 0–1 | Huila | 8,886 | Estadio Nemesio Camacho El Campín | Carlos Mario Herrera | Match Report | |
| 9 | Sun | 2018-03-18 | 14:00 | Boyacá Patriot | 1–0 | Envigado | 2,000 | Estadio de la Independencia | Andrés Rojas | Match Report | |
| 9 | Sun | 2018-03-18 | 16:00 | La Equidad | 2–0 | AD Cali | 1,500 | Estadio Metropolitano de Techo | Diego Escalante | Match Report | |
| 9 | Sun | 2018-03-18 | 17:15 | Junior | 2–0 | Millonarios | 19,167 | Estadio Metropolitano Roberto Meléndez | Luis Sánchez | Match Report | |
| 9 | Sun | 2018-03-18 | 18:00 | Alianza | 4–0 | Jaguares | 3,000 | Estadio Daniel Villa Zapata | John J. Ospina | Match Report | |
| 9 | Sat | 2018-03-17 | 19:45 | Nacional | 2–0 | Pasto | 20,315 | Estadio Atanasio Girardot | Ricardo García | Match Report | |
| 9 | Mon | 2018-03-19 | 15:15 | Leones FC | 0–2 | Independiente | 8,000 | Estadio Metropolitano de Itagüí | Carlos Ortega | Match Report | |
| 9 | Sun | 2018-03-18 | 20:00 | CD América | 2–1 | CA Bucaramanga | 7,257 | Estadio Olímpico Pascual Guerrero | Nicolás Gallo | Match Report | |
| 9 | Mon | 2018-03-19 | 19:30 | Once Caldas | 1–2 | Rionegro | 7,500 | Estadio Palogrande | Heider Castro | Match Report | |
| 8 | Thu | 2018-03-22 | 18:00 | Millonarios | 1–1 | Alianza | 8,388 | Estadio Nemesio Camacho El Campín | Éder Vergara | Match Report | |
| 3 | Wed | 2018-03-21 | 20:00 | Junior | 0–3 | Envigado | 11,809 | Estadio Metropolitano Roberto Meléndez | Gustavo Murillo | Match Report | |
| 3 | Wed | 2018-03-21 | 20:05 | Santa Fe | 3–0 | CD América | 11,186 | Estadio Nemesio Camacho El Campín | Bismark Santiago | Match Report | |
| 8 | Thu | 2018-03-22 | 20:00 | CA Bucaramanga | 0–0 | Nacional | 23,000 | Estadio Alfonso López | Jhon Hinestroza | Match Report | |
| 10 | Sat | 2018-03-24 | 14:00 | Rionegro | 2–1 | La Equidad | 4,500 | Estadio Alberto Grisales | Ervin Otero | Match Report | |
| 10 | Sat | 2018-03-24 | 16:00 | Boyacá Chicó | 3–1 | Santa Fe | 4,600 | Estadio de la Independencia | Heider Castro | Match Report | |
| 10 | Sat | 2018-03-24 | 18:00 | Independiente | 2–2 | Tolima | 18,417 | Estadio Atanasio Girardot | Andrés Rojas | Match Report | |
| 10 | Sat | 2018-03-24 | 18:00 | Junior | 3–0 | Once Caldas | 13,309 | Estadio Metropolitano Roberto Meléndez | Wilmar Roldán | Match Report | |
| 10 | Fri | 2018-03-23 | 19:00 | AD Cali | 2–1 | Leones FC | 6,000 | Estadio Olímpico Pascual Guerrero | Nicolás Rodríguez | Match Report | |
| 10 | Sun | 2018-03-25 | 15:15 | CA Bucaramanga | 4–1 | Alianza | 3,000 | Estadio Alfonso López | Diego Escalante | Match Report | |
| 10 | Sun | 2018-03-25 | 17:15 | Envigado | 2–2 | Nacional | 5,000 | Estadio Polideportivo Sur | Nolberto Ararat | Match Report | |
| 10 | Sun | 2018-03-25 | 17:30 | Huila | 2–0 | Boyacá Patriot | 2,000 | Estadio Manuel Murillo Toro | John J. Ospina | Match Report | |
| 10 | Sat | 2018-03-24 | 20:00 | Pasto | 2–0 | CD América | 8,500 | Estadio Departamental Libertad | Leonard Mosquera | Match Report | |
| 10 | Sun | 2018-03-25 | 19:30 | Millonarios | 1–1 | Jaguares | 10,000 | Estadio Nemesio Camacho El Campín | Óscar Masegosa | Match Report | |
| 11 | Tue | 2018-03-27 | 18:00 | Tolima | 0–1 | AD Cali | 2,000 | Estadio Manuel Murillo Toro | Éder Vergara | Match Report | |
| 11 | Wed | 2018-03-28 | 14:00 | Leones FC | 1–1 | Rionegro | 1,000 | Estadio Metropolitano de Itagüí | Edilson Ariza | Match Report | |
| 11 | Wed | 2018-03-28 | 16:00 | CD América | 0–1 | Envigado | 3,000 | Estadio Olímpico Pascual Guerrero | Carlos Ortega | Match Report | |
| 11 | Wed | 2018-03-28 | 18:00 | La Equidad | 0–0 | Junior | 2,000 | Estadio Metropolitano de Techo | Luis Trujillo | Match Report | |
| 11 | Tue | 2018-03-27 | 20:00 | Santa Fe | 1–0 | Independiente | 6,321 | Estadio Nemesio Camacho El Campín | Ricardo García | Match Report | |
| 11 | Thu | 2018-03-29 | 15:15 | Boyacá Patriot | 2–0 | Boyacá Chicó | 4,500 | Estadio de la Independencia | Gustavo Murillo | Match Report | |
| 11 | Thu | 2018-03-29 | 17:00 | Once Caldas | 0–1 | Millonarios | 13,000 | Estadio Palogrande | Jhon Hinestroza | Match Report | |
| 11 | Thu | 2018-03-29 | 17:30 | Jaguares | 0–1 | CA Bucaramanga | 4,000 | Estadio de Fútbol Jaraguay de Montería | Harold Perilla | Match Report | |
| 11 | Wed | 2018-03-28 | 20:00 | Nacional | 1–0 | Huila | 15,000 | Estadio Atanasio Girardot | Leevan Suárez | Match Report | |
| 11 | Thu | 2018-03-29 | 19:30 | Alianza | 0–2 | Pasto | 3,000 | Estadio Daniel Villa Zapata | Carlos Mario Herrera | Match Report | |
| 12 | Sat | 2018-03-31 | 15:15 | Rionegro | 1–3 | Tolima | 3,000 | Estadio Alberto Grisales | Luis Sánchez | Match Report | |
| 12 | Sat | 2018-03-31 | 17:30 | Junior | 1–0 | Leones FC | 10,931 | Estadio Metropolitano Roberto Meléndez | Nolberto Ararat | Match Report | |
| 12 | Sat | 2018-03-31 | 18:00 | Huila | 4–0 | CD América | 1,500 | Estadio Manuel Murillo Toro | Diego Escalante | Match Report | |
| 12 | Sun | 2018-04-01 | 14:00 | Pasto | 0–1 | Jaguares | 5,500 | Estadio Departamental Libertad | Jorge Duarte | Match Report | |
| 12 | Sun | 2018-04-01 | 16:00 | Once Caldas | 3–2 | La Equidad | 7,300 | Estadio Palogrande | John J. Ospina | Match Report | |
| 12 | Sun | 2018-04-01 | 17:15 | Millonarios | 4–1 | CA Bucaramanga | 10,876 | Estadio Nemesio Camacho El Campín | Ferney Trujillo | Match Report | |
| 12 | Sun | 2018-04-01 | 18:00 | Independiente | 4–1 | Boyacá Patriot | 15,000 | Estadio Atanasio Girardot | Ervin Otero | Match Report | |
| 12 | Sat | 2018-03-31 | 19:45 | AD Cali | 3–0 | Santa Fe | 13,000 | Estadio Olímpico Pascual Guerrero | Leonard Mosquera | Match Report | |
| 12 | Sun | 2018-04-01 | 20:00 | Boyacá Chicó | 1–1 | Nacional | 5,000 | Estadio de la Independencia | Andrés Rojas | Match Report | |
| 12 | Mon | 2018-04-02 | 20:00 | Envigado | 0–0 | Alianza | 1,000 | Estadio Polideportivo Sur | Leevan Suárez | Match Report | |
| 8 | Wed | 2018-04-04 | 19:30 | Huila | 0–0 | Tolima | 1,000 | Estadio Manuel Murillo Toro | Nolberto Ararat | Match Report | |
| 13 | Fri | 2018-04-06 | 18:00 | Jaguares | 2–4 | Envigado | 4,000 | Estadio de Fútbol Jaraguay de Montería | Carlos Mario Herrera | Match Report | |
| 13 | Sat | 2018-04-07 | 14:00 | Leones FC | 0–1 | Once Caldas | 1,000 | Estadio Metropolitano de Itagüí | Ferney Trujillo | Match Report | |
| 13 | Sat | 2018-04-07 | 16:00 | CA Bucaramanga | 3–1 | Pasto | 5,000 | Estadio Alfonso López | Éder Vergara | Match Report | |
| 13 | Sat | 2018-04-07 | 18:00 | Alianza | 2–1 | Huila | 3,000 | Estadio Daniel Villa Zapata | Nicolás Gallo | Match Report | |
| 13 | Sat | 2018-04-07 | 18:00 | CD América | 3–0 | Boyacá Chicó | 5,579 | Estadio Olímpico Pascual Guerrero | Wilmar Roldán | Match Report | |
| 13 | Fri | 2018-04-06 | 20:00 | Boyacá Patriot | 1–3 | AD Cali | 4,500 | Estadio de la Independencia | Diego Escalante | Match Report | |
| 13 | Sun | 2018-04-08 | 17:15 | Nacional | 2–0 | Independiente | 41,746 | Estadio Atanasio Girardot | Bismark Santiago | Match Report | |
| 13 | Sun | 2018-04-08 | 17:30 | Santa Fe | 0–0 | Rionegro | 6,977 | Estadio Nemesio Camacho El Campín | John J. Ospina | Match Report | |
| 13 | Sat | 2018-04-07 | 20:00 | La Equidad | 0–0 | Millonarios | 2,000 | Estadio Metropolitano de Techo | Gustavo Murillo | Match Report | |
| 13 | Sun | 2018-04-08 | 19:30 | Tolima | 2–1 | Junior | 4,000 | Estadio Manuel Murillo Toro | Jhon Hinestroza | Match Report | |
| 14 | Tue | 2018-04-10 | 16:00 | La Equidad | 2–0 | Leones FC | 500 | Estadio Metropolitano de Techo | Ricardo García | Match Report | |
| 14 | Tue | 2018-04-10 | 18:00 | Boyacá Chicó | 3–0 | Alianza | 500 | Estadio de la Independencia | Harold Perilla | Match Report | |
| 14 | Wed | 2018-04-11 | 16:00 | Envigado | 1–1 | CA Bucaramanga | 1,500 | Estadio Polideportivo Sur | Jorge Guzmán | Match Report | |
| 14 | Wed | 2018-04-11 | 18:00 | Once Caldas | 0–1 | Tolima | 8,500 | Estadio Palogrande | Carlos Ortega | Match Report | |
| 14 | Tue | 2018-04-10 | 20:00 | Millonarios | 2–0 | Pasto | 8,580 | Estadio Nemesio Camacho El Campín | Heider Castro | Match Report | |
| 14 | Wed | 2018-04-11 | 20:00 | Junior | 1–1 | Santa Fe | 12,727 | Estadio Metropolitano Roberto Meléndez | Ervin Otero | Match Report | |
| 14 | Thu | 2018-04-12 | 20:00 | Rionegro | 0–1 | Boyacá Patriot | 100 | Estadio Alberto Grisales | Nolberto Ararat | Match Report | |
| 15 | Sat | 2018-04-14 | 14:00 | Tolima | 4–1 | La Equidad | 1,500 | Estadio Manuel Murillo Toro | Edilson Ariza | Match Report | |
| 15 | Sat | 2018-04-14 | 16:00 | Jaguares | 2–0 | Boyacá Chicó | 600 | Estadio de Fútbol Jaraguay de Montería | John J. Ospina | Match Report | |
| 15 | Sat | 2018-04-14 | 17:30 | Santa Fe | 2–2 | Once Caldas | 7,281 | Estadio Nemesio Camacho El Campín | Wilmar Roldán | Match Report | |
| 15 | Sat | 2018-04-14 | 18:00 | CA Bucaramanga | 0–1 | Huila | 5,000 | Estadio Alfonso López | Luis Sánchez | Match Report | |
| 15 | Sun | 2018-04-15 | 14:00 | Pasto | 2–0 | Envigado | 1,000 | Estadio Departamental Libertad | Gustavo Murillo | Match Report | |
| 15 | Sun | 2018-04-15 | 16:00 | Alianza | 2–2 | Independiente | 2,000 | Estadio Daniel Villa Zapata | Jhon Hinestroza | Match Report | |
| 15 | Sun | 2018-04-15 | 18:00 | Boyacá Patriot | 1–0 | Junior | 5,000 | Estadio de la Independencia | Ricardo García | Match Report | |
| 15 | Sat | 2018-04-14 | 20:00 | Leones FC | 2–1 | Millonarios | 3,000 | Estadio Metropolitano de Itagüí | Leevan Suárez | Match Report | |
| 15 | Sat | 2018-04-14 | 20:00 | CD América | 2–1 | AD Cali | 15,600 | Estadio Olímpico Pascual Guerrero | Andrés Rojas | Match Report | |
| 15 | Sun | 2018-04-15 | 20:00 | Nacional | 1–0 | Rionegro | 18,090 | Estadio Atanasio Girardot | Nicolás Gallo | Match Report | |
| 16 | Tue | 2018-04-17 | 18:00 | Leones FC | 0–1 | Tolima | 10,000 | Estadio Metropolitano de Itagüí | Heider Castro | Match Report | |
| 16 | Wed | 2018-04-18 | 16:00 | Huila | 2–0 | Pasto | 1,000 | Estadio Guillermo Plazas Alcid | Jorge Guzmán | Match Report | |
| 16 | Wed | 2018-04-18 | 18:00 | Once Caldas | 2–0 | Boyacá Patriot | 9,000 | Estadio Palogrande | Nolberto Ararat | Match Report | |
| 16 | Tue | 2018-04-17 | 20:00 | Boyacá Chicó | 2–1 | CA Bucaramanga | 650 | Estadio de la Independencia | Diego Escalante | Match Report | |
| 16 | Thu | 2018-04-19 | 18:00 | AD Cali | 2–1 | Alianza | 5,000 | Estadio Deportivo Cali | John J. Ospina | Match Report | |
| 16 | Wed | 2018-04-18 | 20:00 | Independiente | 2–1 | Jaguares | 13,687 | Estadio Atanasio Girardot | Edilson Ariza | Match Report | |
| 16 | Thu | 2018-04-19 | 20:00 | Rionegro | 2–1 | CD América | 3,500 | Estadio Alberto Grisales | Ervin Otero | Match Report | |
| 17 | Sat | 2018-04-21 | 15:15 | Boyacá Patriot | 0–0 | La Equidad | 800 | Estadio de la Independencia | Carlos Mario Herrera | Match Report | |
| 17 | Sat | 2018-04-21 | 17:30 | Tolima | 1–0 | Millonarios | 12,000 | Estadio Manuel Murillo Toro | Bismark Santiago | Match Report | |
| 17 | Sat | 2018-04-21 | 18:00 | CA Bucaramanga | 2–4 | Independiente | 5,000 | Estadio Alfonso López | Ferney Trujillo | Match Report | |
| 17 | Sun | 2018-04-22 | 14:00 | Envigado | 0–3 | Huila | 3,000 | Estadio Polideportivo Sur | Andrés Rojas | Match Report | |
| 17 | Sun | 2018-04-22 | 16:00 | Jaguares | 1–0 | AD Cali | 1,000 | Estadio de Fútbol Jaraguay de Montería | Ricardo García | Match Report | |
| 17 | Sun | 2018-04-22 | 17:15 | CD América | 2–2 | Junior | 11,300 | Estadio Olímpico Pascual Guerrero | Nicolás Gallo | Match Report | |
| 17 | Sun | 2018-04-22 | 18:00 | Alianza | 2–0 | Rionegro | 2,500 | Estadio Daniel Villa Zapata | Never Manjarrés | Match Report | |
| 17 | Sat | 2018-04-21 | 19:45 | Nacional | 1–0 | Once Caldas | 24,017 | Estadio Atanasio Girardot | Luis Sánchez | Match Report | |
| 17 | Sun | 2018-04-22 | 20:00 | Santa Fe | 2–1 | Leones FC | 4,469 | Estadio Nemesio Camacho El Campín | Éder Vergara | Match Report | |
| 17 | Mon | 2018-04-23 | 20:00 | Pasto | 3–0 | Boyacá Chicó | 1,500 | Estadio Departamental Libertad | Jhon Hinestroza | Match Report | |
| 14 | Wed | 2018-04-25 | 18:00 | Huila | 1–2 | Jaguares | 600 | Estadio Guillermo Plazas Alcid | Lisandro Castillo | Match Report | |
| 16 | Thu | 2018-04-26 | 18:00 | La Equidad | 2–0 | Santa Fe | 634 | Estadio Metropolitano de Techo | Diego Escalante | Match Report | |
| 16 | Wed | 2018-04-25 | 20:00 | Junior | 1–1 | Nacional | 15,095 | Estadio Metropolitano Roberto Meléndez | Gustavo Murillo | Match Report | |
| 7 | Thu | 2018-04-26 | 20:00 | CD América | 2–1 | Alianza | 6,000 | Estadio Olímpico Pascual Guerrero | Bismark Santiago | Match Report | |
| 18 | Sat | 2018-04-28 | 14:00 | Boyacá Chicó | 0–1 | Envigado | 500 | Estadio de la Independencia | Jorge Duarte | Match Report | |
| 18 | Sat | 2018-04-28 | 16:00 | Rionegro | 1–1 | Jaguares | 5,000 | Estadio Alberto Grisales | Carlos Betancourt | Match Report | |
| 18 | Sat | 2018-04-28 | 18:00 | Millonarios | 1–0 | Huila | 10,928 | Estadio Nemesio Camacho El Campín | Jhon Hinestroza | Match Report | |
| 18 | Fri | 2018-04-27 | 20:00 | AD Cali | 0–1 | CA Bucaramanga | 5,000 | Estadio Olímpico Pascual Guerrero | Leevan Suárez | Match Report | |
| 18 | Sun | 2018-04-29 | 14:00 | Leones FC | 1–1 | Boyacá Patriot | 4,000 | Estadio Metropolitano de Itagüí | Luis Sánchez | Match Report | |
| 18 | Sun | 2018-04-29 | 16:00 | Tolima | 0–0 | Santa Fe | 8,000 | Estadio Manuel Murillo Toro | Nolberto Ararat | Match Report | |
| 18 | Sun | 2018-04-29 | 17:15 | Junior | 0–0 | Alianza | 22,050 | Estadio Metropolitano Roberto Meléndez | Ferney Trujillo | Match Report | |
| 18 | Sun | 2018-04-29 | 18:00 | La Equidad | 1–0 | Nacional | 6,000 | Estadio Metropolitano de Techo | John J. Ospina | Match Report | |
| 18 | Sat | 2018-04-28 | 20:00 | Independiente | 1–0 | Pasto | 14,266 | Estadio Atanasio Girardot | Luis Trujillo | Match Report | |
| 18 | Sun | 2018-04-29 | 20:00 | Once Caldas | 2–2 | CD América | 20,000 | Estadio Palogrande | Carlos Mario Herrera | Match Report | |
| 16 | Wed | 2018-05-02 | 18:00 | Millonarios | 1–0 | Envigado | 9,213 | Estadio Nemesio Camacho El Campín | John J. Ospina | Match Report | |
| 14 | Wed | 2018-05-02 | 20:00 | AD Cali | 0–2 | Nacional | 18,000 | Estadio Olímpico Pascual Guerrero | Carlos Mario Herrera | Match Report | |
| 14 | Thu | 2018-05-03 | 20:00 | Independiente | 3–1 | CD América | 17,000 | Estadio Atanasio Girardot | Heider Castro | Match Report | |
| 19 | Sun | 2018-05-06 | 14:00 | Envigado | 2–0 | Independiente | 3,500 | Estadio Polideportivo Sur | Carlos Betancourt | Match Report | |
| 19 | Sun | 2018-05-06 | 16:00 | Huila | 0–1 | Boyacá Chicó | 600 | Estadio Guillermo Plazas Alcid | Edilson Ariza | Match Report | |
| 19 | Sun | 2018-05-06 | 18:00 | Santa Fe | 1–0 | Millonarios | 19,214 | Estadio Nemesio Camacho El Campín | Gustavo Murillo | Match Report | |
| 19 | Sun | 2018-05-06 | 18:00 | Boyacá Patriot | 0–0 | Tolima | 2,200 | Estadio de la Independencia | Jorge Guzmán | Match Report | |
| 19 | Sun | 2018-05-06 | 18:00 | CA Bucaramanga | 2–2 | Rionegro | 3,000 | Estadio Alfonso López | Andrés Rojas | Match Report | |
| 19 | Sun | 2018-05-06 | 18:00 | Pasto | 0–0 | AD Cali | 18,000 | Estadio Departamental Libertad | Diego Escalante | Match Report | |
| 19 | Sun | 2018-05-06 | 18:00 | CD América | 1–1 | La Equidad | 3,000 | Estadio Olímpico Pascual Guerrero | Ricardo García | Match Report | |
| 19 | Sun | 2018-05-06 | 18:00 | Jaguares | 1–2 | Junior | 8,000 | Estadio de Fútbol Jaraguay de Montería | Wilmar Roldán | Match Report | |
| 19 | Sun | 2018-05-06 | 18:00 | Alianza | 4–1 | Once Caldas | 2,000 | Estadio Daniel Villa Zapata | Jhon Hinestroza | Match Report | |
| 19 | Sun | 2018-05-06 | 20:00 | Nacional | 1–0 | Leones FC | 18,659 | Estadio Atanasio Girardot | Nolberto Ararat | Match Report |
| Round | Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Quarter-finals | Sat | 2018-05-12 | 18:00 | Boyacá Patriot | 1–1 | Huila | 2,500 | Estadio Guillermo Plazas Alcid | Bismark Santiago | Match Report | Leg 1 of 2 |
| Quarter-finals | Sun | 2018-05-13 | 17:15 | Junior | 0–1 | Independiente | 16,309 | Estadio Metropolitano Roberto Meléndez | Jhon Hinestroza | Match Report | Leg 1 of 2 |
| Quarter-finals | Sat | 2018-05-12 | 20:00 | AD Cali | 1–0 | Nacional | 24,000 | Estadio Deportivo Cali | Nicolás Gallo | Match Report | Leg 1 of 2 |
| Quarter-finals | Sun | 2018-05-13 | 19:30 | Once Caldas | 1–0 | Tolima | 9,500 | Estadio Palogrande | Wilmar Roldán | Match Report | Leg 1 of 2 |
| Quarter-finals | Sat | 2018-05-19 | 18:00 | Nacional | 2–0 | AD Cali | 31,114 | Estadio Atanasio Girardot | Gustavo Murillo | Match Report | Leg 2 of 2; Nacional won |
| Quarter-finals | Sun | 2018-05-20 | 17:15 | Tolima | 3–0 | Once Caldas | 15,000 | Estadio Manuel Murillo Toro | Carlos Betancourt | Match Report | Leg 2 of 2; Tolima won |
| Quarter-finals | Sat | 2018-05-19 | 20:00 | Huila | (3) 0–0 (1) | Boyacá Patriot | 2,000 | Estadio de la Independencia | Andrés Rojas | Match Report | Leg 2 of 2; Huila won; Huila won on penalty kicks following extra time |
| Quarter-finals | Sun | 2018-05-20 | 19:30 | Independiente | 2–2 | Junior | 17,763 | Estadio Atanasio Girardot | Luis Sánchez | Match Report | Leg 2 of 2; Independiente won |
| Semi-finals | Tue | 2018-05-29 | 19:45 | Huila | 0–0 | Nacional | 29,308 | Estadio Nemesio Camacho El Campín | John J. Ospina | Match Report | Leg 1 of 2 |
| Semi-finals | Wed | 2018-05-30 | 19:30 | Tolima | 1–0 | Independiente | 16,000 | Estadio Manuel Murillo Toro | Jhon Hinestroza | Match Report | Leg 1 of 2 |
| Semi-finals | Sat | 2018-06-02 | 18:00 | Nacional | (4) 0–0 (2) | Huila | 24,270 | Estadio Atanasio Girardot | Carlos Betancourt | Match Report | Leg 2 of 2; Nacional won; Nacional won on penalty kicks following extra time |
| Semi-finals | Sun | 2018-06-03 | 17:30 | Independiente | (3) 1–0 (5) | Tolima | 18,398 | Estadio Atanasio Girardot | Nicolás Gallo | Match Report | Leg 2 of 2; Tolima won |
| Finals | Wed | 2018-06-06 | 19:30 | Tolima | 0–1 | Nacional | 25,000 | Estadio Manuel Murillo Toro | Andrés Rojas | Match Report | Leg 1 of 2 |
| Finals | Sat | 2018-06-09 | 19:15 | Nacional | (2) 1–2 (4) | Tolima | 44,695 | Estadio Atanasio Girardot | Luis Sánchez | Match Report | Leg 2 of 2; Tolima won; Tolima won on penalty kicks following extra time |
| Wk | Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Fri | 2018-07-20 | 17:00 | Alianza | 0–2 | La Equidad | 4,000 | Estadio Daniel Villa Zapata | Jorge Tabares | Match Report | |
| 1 | Sat | 2018-07-21 | 17:30 | Pasto | 0–1 | Rionegro | 4,000 | Estadio Departamental Libertad | Luis Trujillo | Match Report | |
| 1 | Sat | 2018-07-21 | 18:00 | CA Bucaramanga | 0–0 | Junior | 7,000 | Estadio Alfonso López | Nolberto Ararat | Match Report | |
| 1 | Sun | 2018-07-22 | 15:00 | Boyacá Patriot | 0–0 | Santa Fe | 6,500 | Estadio de la Independencia | Ferney Trujillo | Match Report | |
| 1 | Sun | 2018-07-22 | 17:00 | Jaguares | 0–1 | Once Caldas | 1,000 | Estadio de Fútbol Jaraguay de Montería | Óscar Masegosa | Match Report | |
| 1 | Sun | 2018-07-22 | 17:15 | Millonarios | 2–2 | Boyacá Chicó | 10,000 | Estadio Nemesio Camacho El Campín | Diego Escalante | Match Report | |
| 1 | Sat | 2018-07-21 | 19:45 | Envigado | 1–1 | AD Cali | 2,000 | Estadio Polideportivo Sur | Bismark Santiago | Match Report | |
| 1 | Tue | 2018-07-24 | 18:00 | Huila | 0–0 | Independiente | 1,000 | Estadio Guillermo Plazas Alcid | Mauricio Palencia | Match Report | |
| 1 | Tue | 2018-07-24 | 20:00 | CD América | 1–0 | Leones FC | 5,211 | Estadio Olímpico Pascual Guerrero | Jorge Guzmán | Match Report | |
| 1 | Wed | 2018-07-25 | 19:45 | Nacional | 1–2 | Tolima | 16,175 | Estadio Atanasio Girardot | Heider Castro | Match Report | |
| 2 | Fri | 2018-07-27 | 18:00 | La Equidad | 2–0 | Jaguares | 2,000 | Estadio Metropolitano de Techo | Edilson Ariza | Match Report | |
| 2 | Sat | 2018-07-28 | 15:15 | Rionegro | 1–1 | Envigado | 1,000 | Estadio Alberto Grisales | Éder Vergara | Match Report | |
| 2 | Sat | 2018-07-28 | 17:30 | AD Cali | 1–0 | Huila | 8,000 | Estadio Deportivo Cali | Carlos Ortega | Match Report | |
| 2 | Sat | 2018-07-28 | 18:00 | Santa Fe | 0–2 | Nacional | 16,004 | Estadio Nemesio Camacho El Campín | Carlos Betancourt | Match Report | |
| 2 | Fri | 2018-07-27 | 20:00 | Once Caldas | 2–1 | CA Bucaramanga | 5,500 | Estadio Palogrande | Nicolás Rodríguez | Match Report | |
| 2 | Sun | 2018-07-29 | 17:15 | Junior | 3–0 | Pasto | 7,465 | Estadio Metropolitano Roberto Meléndez | Lisandro Castillo | Match Report | |
| 2 | Sun | 2018-07-29 | 17:30 | Boyacá Patriot | 0–2 | Millonarios | 10,050 | Estadio de la Independencia | Ricardo García | Match Report | |
| 2 | Sat | 2018-07-28 | 19:45 | Tolima | 1–0 | CD América | 1,207 | Estadio Manuel Murillo Toro | Gustavo Murillo | Match Report | |
| 2 | Sun | 2018-07-29 | 19:30 | Independiente | 2–0 | Boyacá Chicó | 14,000 | Estadio Atanasio Girardot | Carlos Mario Herrera | Match Report | |
| 2 | Mon | 2018-07-30 | 20:00 | Leones FC | 0–1 | Alianza | 1,000 | Estadio Metropolitano de Itagüí | Nicolás Gallo | Match Report | |
| 3 | Wed | 2018-08-01 | 20:00 | Nacional | 0–0 | Boyacá Patriot | 15,000 | Estadio Atanasio Girardot | Carlos Ortega | Match Report | |
| 3 | Sat | 2018-08-04 | 16:00 | Huila | 2–2 | Rionegro | 200 | Estadio Guillermo Plazas Alcid | Heider Castro | Match Report | |
| 3 | Sat | 2018-08-04 | 18:00 | Envigado | 0–1 | Junior | 3,500 | Estadio Polideportivo Sur | Luis Sánchez | Match Report | |
| 3 | Sat | 2018-08-04 | 18:00 | CA Bucaramanga | 0–2 | La Equidad | 7,000 | Estadio Alfonso López | Ferney Trujillo | Match Report | |
| 3 | Sun | 2018-08-05 | 15:15 | Boyacá Chicó | 1–1 | AD Cali | 500 | Estadio de la Independencia | Bismark Santiago | Match Report | |
| 3 | Sun | 2018-08-05 | 17:15 | CD América | 0–0 | Santa Fe | 3,500 | Estadio Olímpico Pascual Guerrero | Diego Escalante | Match Report | |
| 3 | Sun | 2018-08-05 | 17:30 | Pasto | 0–0 | Once Caldas | 3,500 | Estadio Departamental Libertad | Andrés Rojas | Match Report | |
| 3 | Sat | 2018-08-04 | 20:00 | Millonarios | 0–1 | Independiente | 12,570 | Estadio Nemesio Camacho El Campín | Gustavo Murillo | Match Report | |
| 3 | Sun | 2018-08-05 | 19:30 | Alianza | 4–2 | Tolima | 6,000 | Estadio Daniel Villa Zapata | Carlos Mario Herrera | Match Report | |
| 3 | Mon | 2018-08-06 | 19:45 | Jaguares | 2–0 | Leones FC | 1,000 | Estadio de Fútbol Jaraguay de Montería | Carlos Betancur | Match Report | |
| 4 | Sat | 2018-08-11 | 14:00 | Leones FC | 0–1 | CA Bucaramanga | 1,500 | Estadio Metropolitano de Itagüí | Gustavo Murillo | Match Report | |
| 4 | Sat | 2018-08-11 | 16:00 | Rionegro | 1–0 | Boyacá Chicó | 3,500 | Estadio Alberto Grisales | Nolberto Ararat | Match Report | |
| 4 | Sat | 2018-08-11 | 18:00 | Boyacá Patriot | 0–0 | CD América | 7,000 | Estadio de la Independencia | Óscar Masegosa | Match Report | |
| 4 | Sat | 2018-08-11 | 18:00 | Santa Fe | 4–0 | Alianza | 7,548 | Estadio Nemesio Camacho El Campín | Jorge Guzmán | Match Report | |
| 4 | Fri | 2018-08-10 | 19:45 | Tolima | 2–2 | Jaguares | 2,000 | Estadio Manuel Murillo Toro | Lisandro Castillo | Match Report | |
| 4 | Sun | 2018-08-12 | 15:15 | La Equidad | 1–0 | Pasto | 946 | Estadio Metropolitano de Techo | Jorge Duarte | Match Report | |
| 4 | Sun | 2018-08-12 | 17:30 | Once Caldas | 3–1 | Envigado | 6,153 | Estadio Palogrande | Carlos Mario Herrera | Match Report | |
| 4 | Sat | 2018-08-11 | 20:00 | AD Cali | 3–2 | Independiente | 20,000 | Estadio Deportivo Cali | Ricardo García | Match Report | |
| 4 | Sun | 2018-08-12 | 19:30 | Nacional | 1–1 | Millonarios | 21,433 | Estadio Atanasio Girardot | John J. Ospina | Match Report | |
| 4 | Sun | 2018-08-12 | 19:30 | Junior | 3–0 | Huila | 6,318 | Estadio Metropolitano Roberto Meléndez | Nicolás Rodríguez | Match Report | |
| 5 | Sat | 2018-08-18 | 15:15 | Alianza | 3–2 | Boyacá Patriot | 2,000 | Estadio Daniel Villa Zapata | Diego Escalante | Match Report | |
| 5 | Sat | 2018-08-18 | 17:30 | CD América | 0–2 | Nacional | 8,500 | Estadio Olímpico Pascual Guerrero | Nicolás Gallo | Match Report | |
| 5 | Sat | 2018-08-18 | 18:00 | Boyacá Chicó | 2–1 | Junior | 2,000 | Estadio de la Independencia | Jorge Guzmán | Match Report | |
| 5 | Sun | 2018-08-19 | 16:00 | Independiente | 1–0 | Rionegro | 13,042 | Estadio Atanasio Girardot | John J. Ospina | Match Report | |
| 5 | Sun | 2018-08-19 | 17:15 | Millonarios | 0–0 | AD Cali | 16,649 | Estadio Nemesio Camacho El Campín | Wilmar Roldán | Match Report | |
| 5 | Sun | 2018-08-19 | 18:00 | Huila | 1–2 | Once Caldas | 300 | Estadio Guillermo Plazas Alcid | Bismark Santiago | Match Report | |
| 5 | Sat | 2018-08-18 | 19:45 | CA Bucaramanga | 0–2 | Tolima | 2,000 | Estadio Alfonso López | Carlos Betancourt | Match Report | |
| 5 | Mon | 2018-08-20 | 17:30 | Envigado | 0–1 | La Equidad | 1,500 | Estadio Polideportivo Sur | Luis Trujillo | Match Report | |
| 5 | Sun | 2018-08-19 | 20:00 | Jaguares | 0–0 | Santa Fe | 3,000 | Estadio de Fútbol Jaraguay de Montería | Luis Sánchez | Match Report | |
| 5 | Tue | 2018-08-21 | 19:30 | Pasto | 2–1 | Leones FC | 1,500 | Estadio Departamental Libertad | Carlos Ortega | Match Report | |
| 6 | Fri | 2018-08-24 | 18:00 | La Equidad | 1–0 | Huila | 3,000 | Estadio Metropolitano de Techo | Gustavo Murillo | Match Report | |
| 6 | Sat | 2018-08-25 | 14:00 | Leones FC | 1–1 | Envigado | 2,000 | Estadio Metropolitano de Itagüí | Óscar Masegosa | Match Report | |
| 6 | Sat | 2018-08-25 | 16:00 | Santa Fe | 1–1 | CA Bucaramanga | 8,970 | Estadio Nemesio Camacho El Campín | Carlos Ortega | Match Report | |
| 6 | Sat | 2018-08-25 | 16:00 | Rionegro | 2–0 | AD Cali | 4,500 | Estadio Alberto Grisales | Andrés Rojas | Match Report | |
| 6 | Sat | 2018-08-25 | 18:00 | CD América | 0–2 | Millonarios | 5,580 | Estadio Olímpico Pascual Guerrero | Jorge Guzmán | Match Report | |
| 6 | Sat | 2018-08-25 | 18:00 | Once Caldas | 3–1 | Boyacá Chicó | 7,091 | Estadio Palogrande | Heider Castro | Match Report | |
| 6 | Fri | 2018-08-24 | 20:00 | Nacional | 3–2 | Alianza | 13,766 | Estadio Atanasio Girardot | Nicolás Rodríguez | Match Report | |
| 6 | Sat | 2018-08-25 | 20:00 | Junior | 2–1 | Independiente | 10,780 | Estadio Metropolitano Roberto Meléndez | Nicolás Gallo | Match Report | |
| 6 | Mon | 2018-08-27 | 18:00 | Boyacá Patriot | 4–0 | Jaguares | 1,000 | Estadio de la Independencia | Jorge Tabares | Match Report | |
| 6 | Mon | 2018-08-27 | 20:00 | Tolima | 1–0 | Pasto | 3,000 | Estadio Manuel Murillo Toro | Ferney Trujillo | Match Report | |
| 7 | Sat | 2018-09-01 | 14:00 | Boyacá Chicó | 0–1 | La Equidad | 500 | Estadio de la Independencia | Bismark Santiago | Match Report | |
| 7 | Sat | 2018-09-01 | 16:00 | Huila | 2–3 | Leones FC | 200 | Estadio Guillermo Plazas Alcid | John J. Ospina | Match Report | |
| 7 | Sat | 2018-09-01 | 18:00 | Envigado | 1–3 | Tolima | 1,000 | Estadio Polideportivo Sur | Nolberto Ararat | Match Report | |
| 7 | Sat | 2018-09-01 | 18:00 | Millonarios | 1–1 | Rionegro | 11,376 | Estadio Nemesio Camacho El Campín | Nicolás Gallo | Match Report | |
| 7 | Sun | 2018-09-02 | 14:00 | Pasto | 1–1 | Santa Fe | 4,500 | Estadio Departamental Libertad | Luis Trujillo | Match Report | |
| 7 | Sun | 2018-09-02 | 16:00 | CA Bucaramanga | 2–1 | Boyacá Patriot | 5,000 | Estadio Alfonso López | Luis Sánchez | Match Report | |
| 7 | Sun | 2018-09-02 | 17:15 | Independiente | 2–2 | Once Caldas | 15,384 | Estadio Atanasio Girardot | Gustavo Murillo | Match Report | |
| 7 | Sun | 2018-09-02 | 18:00 | Jaguares | 1–1 | Nacional | 8,000 | Estadio de Fútbol Jaraguay de Montería | Carlos Mario Herrera | Match Report | |
| 7 | Sat | 2018-09-01 | 20:00 | Alianza | 2–2 | CD América | 7,000 | Estadio Daniel Villa Zapata | Jhon Hinestroza | Match Report | |
| 7 | Sun | 2018-09-02 | 20:00 | AD Cali | 1–0 | Junior | 6,000 | Estadio Deportivo Cali | Diego Escalante | Match Report | |
| 8 | Tue | 2018-09-04 | 16:00 | Leones FC | 1–2 | Boyacá Chicó | 500 | Estadio Metropolitano de Itagüí | Éder Vergara | Match Report | |
| 8 | Tue | 2018-09-04 | 18:00 | Tolima | 2–0 | Huila | 2,000 | Estadio Manuel Murillo Toro | Edilson Ariza | Match Report | |
| 8 | Wed | 2018-09-05 | 16:00 | Boyacá Patriot | 1–1 | Pasto | 1,000 | Estadio de la Independencia | Nolberto Ararat | Match Report | |
| 8 | Wed | 2018-09-05 | 18:00 | CD América | 2–1 | Jaguares | 200 | Estadio Olímpico Pascual Guerrero | Nicolás Rodríguez | Match Report | |
| 8 | Wed | 2018-09-05 | 18:00 | Santa Fe | 3–1 | Envigado | 8,970 | Estadio Nemesio Camacho El Campín | Ferney Trujillo | Match Report | |
| 8 | Tue | 2018-09-04 | 20:00 | Alianza | 3–2 | Millonarios | 4,000 | Estadio Daniel Villa Zapata | Bismark Santiago | Match Report | |
| 8 | Thu | 2018-09-06 | 18:00 | Once Caldas | 3–1 | AD Cali | 8,992 | Estadio Palogrande | Jhon Hinestroza | Match Report | |
| 8 | Thu | 2018-09-06 | 18:00 | Junior | 2–0 | Rionegro | 2,949 | Estadio Metropolitano Roberto Meléndez | Ricardo García | Match Report | |
| 8 | Wed | 2018-09-05 | 20:00 | Nacional | 2–3 | CA Bucaramanga | 10,322 | Estadio Atanasio Girardot | Jorge Guzmán | Match Report | |
| 8 | Thu | 2018-09-06 | 20:00 | La Equidad | 1–1 | Independiente | 2,000 | Estadio Metropolitano de Techo | Carlos Mario Herrera | Match Report | |
| 9 | Sat | 2018-09-08 | 15:15 | Jaguares | 1–0 | Alianza | 2,000 | Estadio de Fútbol Jaraguay de Montería | Gustavo Murillo | Match Report | |
| 9 | Sat | 2018-09-08 | 17:30 | Boyacá Chicó | 2–1 | Tolima | 500 | Estadio de la Independencia | Carlos Ortega | Match Report | |
| 9 | Sat | 2018-09-08 | 18:00 | CA Bucaramanga | 2–3 | CD América | 21,000 | Estadio Alfonso López | Bismark Santiago | Match Report | |
| 9 | Sun | 2018-09-09 | 13:15 | Envigado | 2–1 | Boyacá Patriot | 1,500 | Estadio Polideportivo Sur | Lisandro Castillo | Match Report | |
| 9 | Sun | 2018-09-09 | 15:15 | Independiente | 1–1 | Leones FC | 11,263 | Estadio Atanasio Girardot | Jorge Duarte | Match Report | |
| 9 | Sun | 2018-09-09 | 17:15 | AD Cali | 3–0 | La Equidad | 5,000 | Estadio Deportivo Cali | Edilson Ariza | Match Report | |
| 9 | Sun | 2018-09-09 | 17:30 | Pasto | 0–2 | Nacional | 10,000 | Estadio Departamental Libertad | Heider Castro | Match Report | |
| 9 | Sat | 2018-09-08 | 19:45 | Huila | 0–1 | Santa Fe | 500 | Estadio Guillermo Plazas Alcid | Óscar Masegosa | Match Report | |
| 9 | Mon | 2018-09-10 | 18:00 | Rionegro | 1–0 | Once Caldas | 5,500 | Estadio Alberto Grisales | Nolberto Ararat | Match Report | |
| 9 | Sun | 2018-09-09 | 19:30 | Millonarios | 1–1 | Junior | 12,316 | Estadio Nemesio Camacho El Campín | Luis Sánchez | Match Report | |
| 10 | Sat | 2018-09-15 | 14:00 | Leones FC | 0–0 | AD Cali | 1,000 | Estadio Metropolitano de Itagüí | Carlos Ortega | Match Report | |
| 10 | Sat | 2018-09-15 | 16:00 | Jaguares | 1–2 | Millonarios | 1,000 | Estadio de Fútbol Jaraguay de Montería | Carlos Betancourt | Match Report | |
| 10 | Sat | 2018-09-15 | 18:00 | CD América | 3–1 | Pasto | 9,842 | Estadio Olímpico Pascual Guerrero | Lisandro Castillo | Match Report | |
| 10 | Sat | 2018-09-15 | 18:00 | Santa Fe | 2–0 | Boyacá Chicó | 6,000 | Estadio Nemesio Camacho El Campín | Edilson Ariza | Match Report | |
| 10 | Fri | 2018-09-14 | 20:00 | Boyacá Patriot | 1–0 | Huila | 2,500 | Estadio de la Independencia | Luis Trujillo | Match Report | |
| 10 | Sun | 2018-09-16 | 16:00 | La Equidad | 0–2 | Rionegro | 559 | Estadio Metropolitano de Techo | Ferney Trujillo | Match Report | |
| 10 | Sun | 2018-09-16 | 17:15 | Once Caldas | 1–0 | Junior | 9,950 | Estadio Palogrande | Jorge Duarte | Match Report | |
| 10 | Sun | 2018-09-16 | 18:00 | Alianza | 1–2 | CA Bucaramanga | 6,000 | Estadio Daniel Villa Zapata | Óscar Masegosa | Match Report | |
| 10 | Sat | 2018-09-15 | 20:00 | Tolima | 3–0 | Independiente | 9,000 | Estadio Manuel Murillo Toro | Heider Castro | Match Report | |
| 10 | Sun | 2018-09-16 | 20:00 | Nacional | 3–1 | Envigado | 14,114 | Estadio Atanasio Girardot | Ricardo García | Match Report | |
| 11 | Fri | 2018-09-21 | 18:00 | CA Bucaramanga | 2–1 | Jaguares | 3,000 | Estadio Alfonso López | Nolberto Ararat | Match Report | |
| 11 | Sat | 2018-09-22 | 15:15 | Junior | 3–1 | La Equidad | 2,950 | Estadio Romelio Martínez | Wilmar Roldán | Match Report | |
| 11 | Sat | 2018-09-22 | 17:30 | Rionegro | 2–1 | Leones FC | 5,000 | Estadio Alberto Grisales | Bismark Santiago | Match Report | |
| 11 | Sat | 2018-09-22 | 18:00 | Independiente | 2–2 | Santa Fe | 11,861 | Estadio Atanasio Girardot | Nicolás Gallo | Match Report | |
| 11 | Fri | 2018-09-21 | 20:00 | Boyacá Chicó | 1–1 | Boyacá Patriot | 2,500 | Estadio de la Independencia | Jhon Hinestroza | Match Report | |
| 11 | Sun | 2018-09-23 | 17:15 | AD Cali | 0–1 | Tolima | 10,000 | Estadio Alfonso López | Andrés Rojas | Match Report | |
| 11 | Sun | 2018-09-23 | 17:30 | Pasto | 2–1 | Alianza | 3,000 | Estadio Departamental Libertad | Carlos Ortega | Match Report | |
| 11 | Sat | 2018-09-22 | 19:45 | Millonarios | 2–2 | Once Caldas | 10,813 | Estadio Nemesio Camacho El Campín | Diego Escalante | Match Report | |
| 11 | Sun | 2018-09-23 | 19:30 | Huila | 1–0 | Nacional | 1,500 | Estadio Guillermo Plazas Alcid | Carlos Betancourt | Match Report | |
| 11 | Mon | 2018-09-24 | 19:45 | Envigado | 1–1 | CD América | 3,500 | Estadio Polideportivo Sur | Éder Vergara | Match Report | |
| 12 | Sat | 2018-09-29 | 14:00 | Leones FC | 2–2 | Junior | 500 | Estadio Metropolitano de Itagüí | Carlos Betancourt | Match Report | |
| 12 | Sat | 2018-09-29 | 16:00 | Tolima | 1–1 | Rionegro | 3,000 | Estadio Manuel Murillo Toro | Nicolás Rodríguez | Match Report | |
| 12 | Sat | 2018-09-29 | 18:00 | Santa Fe | 0–2 | AD Cali | 9,687 | Estadio Nemesio Camacho El Campín | Wilmar Roldán | Match Report | |
| 12 | Sat | 2018-09-29 | 18:00 | Alianza | 1–2 | Envigado | 2,000 | Estadio Daniel Villa Zapata | Carlos Mario Herrera | Match Report | |
| 12 | Fri | 2018-09-28 | 20:00 | Boyacá Patriot | 0–3 | Independiente | 500 | Estadio de la Independencia | Ferney Trujillo | Match Report | |
| 12 | Sun | 2018-09-30 | 15:15 | Jaguares | 0–2 | Pasto | 1,000 | Estadio de Fútbol Jaraguay de Montería | Andrés Rojas | Match Report | |
| 12 | Sun | 2018-09-30 | 17:15 | CD América | 0–0 | Huila | 16,800 | Estadio Olímpico Pascual Guerrero | Heider Castro | Match Report | |
| 12 | Sun | 2018-09-30 | 17:30 | Nacional | 3–2 | Boyacá Chicó | 13,955 | Estadio Atanasio Girardot | Nicolás Gallo | Match Report | |
| 12 | Sat | 2018-09-29 | 20:00 | CA Bucaramanga | 2–1 | Millonarios | 22,000 | Estadio Alfonso López | Jhon Hinestroza | Match Report | |
| 12 | Sun | 2018-09-30 | 19:30 | La Equidad | 1–1 | Once Caldas | 1,722 | Estadio Metropolitano de Techo | Ricardo García | Match Report | |
| 13 | Sat | 2018-10-06 | 15:15 | Huila | 2–1 | Alianza | 300 | Estadio Guillermo Plazas Alcid | Lisandro Castillo | Match Report | |
| 13 | Sat | 2018-10-06 | 17:30 | Independiente | 2–1 | Nacional | 29,929 | Estadio Atanasio Girardot | Andrés Rojas | Match Report | |
| 13 | Sat | 2018-10-06 | 18:00 | AD Cali | 0–2 | Boyacá Patriot | 6,000 | Estadio Deportivo Cali | Nicolás Rodríguez | Match Report | |
| 13 | Sun | 2018-10-07 | 17:15 | Boyacá Chicó | 2–1 | CD América | 3,500 | Estadio de la Independencia | Carlos Mario Herrera | Match Report | |
| 13 | Sun | 2018-10-07 | 17:15 | Envigado | 1–0 | Jaguares | 3,000 | Estadio Polideportivo Sur | Ferney Trujillo | Match Report | |
| 13 | Sat | 2018-10-06 | 19:45 | Rionegro | 0–3 | Santa Fe | 6,000 | Estadio Alberto Grisales | Edilson Ariza | Match Report | |
| 13 | Mon | 2018-10-08 | 18:00 | Once Caldas | 0–0 | Leones FC | 6,500 | Estadio Palogrande | Luis Trujillo | Match Report | |
| 13 | Sun | 2018-10-07 | 19:30 | Pasto | 0–1 | CA Bucaramanga | 2,000 | Estadio Departamental Libertad | Carlos Betancourt | Match Report | |
| 13 | Mon | 2018-10-08 | 20:00 | Millonarios | 2–3 | La Equidad | 7,695 | Estadio Nemesio Camacho El Campín | Bismark Santiago | Match Report | |
| 13 | Tue | 2018-10-09 | 19:30 | Junior | 4–3 | Tolima | 9,721 | Estadio Metropolitano Roberto Meléndez | Jhon Hinestroza | Match Report | |
| 14 | Fri | 2018-10-12 | 16:00 | Boyacá Patriot | 0–1 | Rionegro | 1,000 | Estadio de la Independencia | Andrés Rojas | Match Report | |
| 14 | Sat | 2018-10-13 | 15:15 | Jaguares | 0–0 | Huila | 1,200 | Estadio de Fútbol Jaraguay de Montería | Edilson Ariza | Match Report | |
| 14 | Sat | 2018-10-13 | 17:30 | Alianza | 1–0 | Boyacá Chicó | 3,500 | Estadio Daniel Villa Zapata | Wilmar Roldán | Match Report | |
| 14 | Sun | 2018-10-14 | 15:15 | Leones FC | 0–1 | La Equidad | 3,000 | Estadio Metropolitano de Itagüí | Éder Vergara | Match Report | |
| 14 | Sun | 2018-10-14 | 17:15 | Nacional | 0–0 | AD Cali | 19,140 | Estadio Atanasio Girardot | Carlos Mario Herrera | Match Report | |
| 14 | Sun | 2018-10-14 | 17:30 | CA Bucaramanga | 2–1 | Envigado | 10,000 | Estadio Alfonso López | Heider Castro | Match Report | |
| 14 | Sat | 2018-10-13 | 19:45 | Santa Fe | 2–2 | Junior | 10,000 | Estadio Nemesio Camacho El Campín | Jorge Guzmán | Match Report | |
| 14 | Mon | 2018-10-15 | 18:00 | Pasto | 0–1 | Millonarios | 3,000 | Estadio Departamental Libertad | Gustavo Murillo | Match Report | |
| 14 | Sun | 2018-10-14 | 19:30 | CD América | 1–2 | Independiente | 10,000 | Estadio Olímpico Pascual Guerrero | Bismark Santiago | Match Report | |
| 15 | Wed | 2018-10-17 | 16:00 | Huila | 0–2 | CA Bucaramanga | 500 | Estadio Guillermo Plazas Alcid | Luis Trujillo | Match Report | |
| 15 | Wed | 2018-10-17 | 18:00 | Junior | 4–0 | Boyacá Patriot | 5,328 | Estadio Romelio Martínez | Óscar Masegosa | Match Report | |
| 15 | Wed | 2018-10-17 | 18:00 | La Equidad | 0–1 | Tolima | 1,849 | Estadio Metropolitano de Techo | Wilmar Roldán | Match Report | |
| 15 | Thu | 2018-10-18 | 16:00 | Envigado | 1–0 | Pasto | 1,500 | Estadio Polideportivo Sur | Nicolás Rodríguez | Match Report | |
| 15 | Thu | 2018-10-18 | 18:00 | AD Cali | 1–0 | CD América | 15,000 | Estadio Deportivo Cali | Jhon Hinestroza | Match Report | |
| 15 | Wed | 2018-10-17 | 20:00 | Once Caldas | 1–0 | Santa Fe | 10,900 | Estadio Palogrande | Carlos Mario Herrera | Match Report | |
| 15 | Wed | 2018-10-17 | 20:00 | Boyacá Chicó | 1–0 | Jaguares | 270 | Estadio de la Independencia | Jhon Hinestroza | Match Report | |
| 15 | Wed | 2018-10-17 | 20:00 | Independiente | 2–0 | Alianza | 11,710 | Estadio Atanasio Girardot | Luis Sánchez | Match Report | |
| 15 | Thu | 2018-10-18 | 20:00 | Rionegro | 1–3 | Nacional | 3,000 | Estadio Alberto Grisales | Ricardo García | Match Report | |
| 15 | Thu | 2018-10-18 | 20:00 | Millonarios | 1–0 | Leones FC | 12,000 | Estadio Nemesio Camacho El Campín | Ferney Trujillo | Match Report | |
| 16 | Sat | 2018-10-20 | 15:15 | Jaguares | 0–2 | Independiente | 3,000 | Estadio de Fútbol Jaraguay de Montería | Heider Castro | Match Report | |
| 16 | Sat | 2018-10-20 | 17:30 | CA Bucaramanga | 3–0 | Boyacá Chicó | 10,000 | Estadio Alfonso López | Gustavo Murillo | Match Report | |
| 16 | Sat | 2018-10-20 | 18:00 | Santa Fe | 0–1 | La Equidad | 11,124 | Estadio Nemesio Camacho El Campín | Andrés Rojas | Match Report | |
| 16 | Sun | 2018-10-21 | 14:00 | Tolima | 3–2 | Leones FC | 2,500 | Estadio Manuel Murillo Toro | Luis Sánchez | Match Report | |
| 16 | Sun | 2018-10-21 | 16:00 | CD América | 2–1 | Rionegro | 2,300 | Estadio Olímpico Pascual Guerrero | Carlos Ortega | Match Report | |
| 16 | Sun | 2018-10-21 | 17:15 | Nacional | 1–0 | Junior | 22,000 | Estadio Atanasio Girardot | Jhon Hinestroza | Match Report | |
| 16 | Sun | 2018-10-21 | 18:00 | Alianza | 2–0 | AD Cali | 2,000 | Estadio Daniel Villa Zapata | Ferney Trujillo | Match Report | |
| 16 | Sat | 2018-10-20 | 19:45 | Boyacá Patriot | 1–0 | Once Caldas | 1,000 | Estadio de la Independencia | Edilson Ariza | Match Report | |
| 16 | Mon | 2018-10-22 | 18:00 | Pasto | 0–0 | Huila | 1,000 | Estadio Departamental Libertad | Wilmar Roldán | Match Report | |
| 16 | Sun | 2018-10-21 | 20:00 | Envigado | 1–2 | Millonarios | 1,000 | Estadio Polideportivo Sur | Jorge Guzmán | Match Report | |
| 17 | Fri | 2018-10-26 | 18:00 | Boyacá Chicó | 1–1 | Pasto | 500 | Estadio de la Independencia | Éder Vergara | Match Report | |
| 17 | Sat | 2018-10-27 | 14:00 | Leones FC | 0–2 | Santa Fe | 3,500 | Estadio Metropolitano de Itagüí | Nolberto Ararat | Match Report | |
| 17 | Sat | 2018-10-27 | 16:00 | AD Cali | 4–0 | Jaguares | 1,200 | Estadio Deportivo Cali | Edilson Ariza | Match Report | |
| 17 | Sat | 2018-10-27 | 18:00 | Rionegro | 1–0 | Alianza | 6,000 | Estadio Alberto Grisales | Carlos Mario Herrera | Match Report | |
| 17 | Sat | 2018-10-27 | 18:00 | Millonarios | 1–1 | Tolima | 15,880 | Estadio Nemesio Camacho El Campín | Wilmar Roldán | Match Report | |
| 17 | Sun | 2018-10-28 | 14:00 | La Equidad | 4–0 | Boyacá Patriot | 780 | Estadio Metropolitano de Techo | Jorge Tabares | Match Report | |
| 17 | Sun | 2018-10-28 | 17:15 | Junior | 0–0 | CD América | 17,627 | Estadio Metropolitano Roberto Meléndez | Andrés Rojas | Match Report | |
| 17 | Sun | 2018-10-28 | 18:00 | Huila | 2–1 | Envigado | 1,500 | Estadio Guillermo Plazas Alcid | Gustavo Murillo | Match Report | |
| 17 | Sat | 2018-10-27 | 20:00 | Once Caldas | 2–0 | Nacional | 1,549 | Estadio Palogrande | Luis Sánchez | Match Report | |
| 17 | Sun | 2018-10-28 | 20:00 | Independiente | 2–0 | CA Bucaramanga | 23,714 | Estadio Atanasio Girardot | Carlos Ortega | Match Report | |
| 18 | Sat | 2018-11-03 | 15:15 | Santa Fe | 3–0 | Tolima | 8,728 | Estadio Nemesio Camacho El Campín | Gustavo Murillo | Match Report | |
| 18 | Sat | 2018-11-03 | 17:30 | Envigado | 1–0 | Boyacá Chicó | 500 | Estadio Polideportivo Sur | Jonathan Ortíz | Match Report | |
| 18 | Sat | 2018-11-03 | 18:00 | CA Bucaramanga | 1–0 | AD Cali | 20,000 | Estadio Alfonso López | Wilmar Roldán | Match Report | |
| 18 | Sun | 2018-11-04 | 14:00 | Boyacá Patriot | 2–1 | Leones FC | 130 | Estadio de la Independencia | Lisandro Castillo | Match Report | |
| 18 | Sun | 2018-11-04 | 16:00 | Jaguares | 2–2 | Rionegro | 1,000 | Estadio de Fútbol Jaraguay de Montería | Ferney Trujillo | Match Report | |
| 18 | Sun | 2018-11-04 | 18:00 | CD América | 1–1 | Once Caldas | 3,604 | Estadio Olímpico Pascual Guerrero | Heider Castro | Match Report | |
| 18 | Sat | 2018-11-03 | 19:15 | Huila | 1–0 | Millonarios | 1,500 | Estadio Guillermo Plazas Alcid | Nicolás Gallo | Match Report | |
| 18 | Mon | 2018-11-05 | 18:00 | Nacional | 0–0 | La Equidad | 21,593 | Estadio Atanasio Girardot | Edilson Ariza | Match Report | |
| 18 | Sun | 2018-11-04 | 20:00 | Pasto | 1–1 | Independiente | 2,000 | Estadio Departamental Libertad | Jorge Guzmán | Match Report | |
| 18 | Mon | 2018-11-05 | 19:30 | Alianza | 0–3 | Junior | 7,000 | Estadio Daniel Villa Zapata | Nolberto Ararat | Match Report | |
| 14 | Wed | 2018-11-07 | 19:30 | Tolima | 3–0 | Once Caldas | 5,000 | Estadio Manuel Murillo Toro | Carlos Betancourt | Match Report | |
| 19 | Sat | 2018-11-10 | 15:15 | Tolima | 2–1 | Boyacá Patriot | 2,000 | Estadio Manuel Murillo Toro | Luis Trujillo | Match Report | |
| 19 | Sat | 2018-11-10 | 17:30 | Once Caldas | 1–0 | Alianza | 5,727 | Estadio Palogrande | Nicolás Rodríguez | Match Report | |
| 19 | Sat | 2018-11-10 | 18:00 | La Equidad | 1–2 | CD América | 5,000 | Estadio Metropolitano de Techo | Éder Vergara | Match Report | |
| 19 | Fri | 2018-11-09 | 19:45 | Boyacá Chicó | 2–2 | Huila | 1,000 | Estadio de la Independencia | Diego Escalante | Match Report | |
| 19 | Sun | 2018-11-11 | 17:30 | AD Cali | 1–0 | Pasto | 10,764 | Estadio Deportivo Cali | Carlos Mario Herrera | Match Report | |
| 19 | Sun | 2018-11-11 | 17:30 | Leones FC | 2–2 | Nacional | 4,000 | Estadio Metropolitano de Itagüí | Carlos Ortega | Match Report | |
| 19 | Sun | 2018-11-11 | 17:30 | Millonarios | 0–3 | Santa Fe | 10,764 | Estadio Nemesio Camacho El Campín | Bismark Santiago | Match Report | |
| 19 | Sun | 2018-11-11 | 17:30 | Rionegro | 1–0 | CA Bucaramanga | 6,000 | Estadio Alberto Grisales | Nicolás Gallo | Match Report | |
| 19 | Sat | 2018-11-10 | 19:45 | Independiente | 2–2 | Envigado | 15,394 | Estadio Atanasio Girardot | Nolberto Ararat | Match Report | |
| 19 | Sun | 2018-11-11 | 19:45 | Junior | 1–2 | Jaguares | 6,000 | Estadio Metropolitano Roberto Meléndez | Jorge Tabares | Match Report |
| Round | Day | Date | Time | Home | Score | Away | Attendance | Venue | Referee | Match Report | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Quarter-finals | Wed | 2018-11-14 | 20:00 | Santa Fe | 1–2 | Tolima | 22,000 | Estadio Nemesio Camacho El Campín | Nicolás Gallo | Match Report | Leg 1 of 2 |
| Quarter-finals | Wed | 2018-11-14 | 20:00 | Independiente | 3–0 | CA Bucaramanga | 22,000 | Estadio Atanasio Girardot | Luis Sánchez | Match Report | Leg 1 of 2 |
| Quarter-finals | Thu | 2018-11-15 | 19:00 | Rionegro | 1–0 | Once Caldas | 9,419 | Estadio Alberto Grisales | Carlos Mario Herrera | Match Report | Leg 1 of 2 |
| Quarter-finals | Thu | 2018-11-15 | 20:00 | Junior | 1–0 | La Equidad | 7,796 | Estadio Metropolitano Roberto Meléndez | Wilmar Roldán | Match Report | Leg 1 of 2 |
| Quarter-finals | Sat | 2018-11-17 | 18:00 | CA Bucaramanga | 2–0 | Independiente | 20,000 | Estadio Alfonso López | Gustavo Murillo | Match Report | Leg 2 of 2; Independiente won |
| Quarter-finals | Sun | 2018-11-18 | 17:15 | Once Caldas | 1–1 | Rionegro | 10,000 | Estadio Palogrande | Luis Sánchez | Match Report | Leg 2 of 2; Rionegro won |
| Quarter-finals | Sat | 2018-11-17 | 20:00 | Tolima | (4) 0–1 (3) | Santa Fe | 20,000 | Estadio Manuel Murillo Toro | Bismark Santiago | Match Report | Leg 2 of 2; Tolima won; Tolima won on penalty kicks following extra time |
| Quarter-finals | Sun | 2018-11-18 | 19:30 | La Equidad | 0–0 | Junior | 5,000 | Estadio Metropolitano de Techo | Carlos Betancourt | Match Report | Leg 2 of 2; Junior won |
| Semi-finals | Wed | 2018-11-21 | 19:00 | Independiente | 2–2 | Tolima | 22,876 | Estadio Atanasio Girardot | Carlos Betancourt | Match Report | Leg 1 of 2 |
| Semi-finals | Thu | 2018-11-22 | 19:45 | Rionegro | 2–3 | Junior | 5,000 | Estadio Alberto Grisales | Andrés Rojas | Match Report | Leg 1 of 2 |
| Semi-finals | Sun | 2018-11-25 | 17:15 | Junior | 1–1 | Rionegro | 18,965 | Estadio Metropolitano Roberto Meléndez | Carlos Mario Herrera | Match Report | Leg 2 of 2; Junior won |
| Semi-finals | Sun | 2018-11-25 | 19:30 | Tolima | 0–2 | Independiente | 25,000 | Estadio Manuel Murillo Toro | Luis Sánchez | Match Report | Leg 2 of 2; Independiente won |
| Finals | Sat | 2018-12-08 | 19:00 | Junior | 4–1 | Independiente | 40,072 | Estadio Metropolitano Roberto Meléndez | Jhon Hinestroza | Match Report | Leg 1 of 2 |
| Finals | Sun | 2018-12-16 | 16:30 | Independiente | 3–1 | Junior | 43,445 | Estadio Atanasio Girardot | Carlos Betancourt | Match Report | Leg 2 of 2; Junior won |
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