| Regular Season | Sat | 2021-04-17 | 14:00 | CF Montréal | 1.7 | 4–2 | 2.0 | Toronto FC | | Lockhart Stadium | Ismail Elfath | Match Report | |
|---|
| Regular Season | Sat | 2021-04-17 | 15:00 | Orlando City | 1.2 | 0–0 | 0.8 | Atlanta Utd | 11,503 | Exploria Stadium | Jair Marrufo | Match Report | |
|---|
| Regular Season | Sat | 2021-04-17 | 15:00 | Los Angeles FC | 2.4 | 2–0 | 1.2 | Austin | 4,900 | Banc of California Stadium | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Fri | 2021-04-16 | 18:30 | Seattle | 2.9 | 4–0 | 1.3 | Minnesota Utd | 7,042 | Lumen Field | Joe Dickerson | Match Report | |
|---|
| Regular Season | Fri | 2021-04-16 | 19:00 | Houston Dynamo | 1.5 | 2–1 | 1.3 | San Jose | | PNC Stadium | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sun | 2021-04-18 | 15:00 | Inter Miami | 2.8 | 2–3 | 1.3 | LA Galaxy | | Lockhart Stadium | Chris Penso | Match Report | |
|---|
| Regular Season | Sun | 2021-04-18 | 17:30 | Columbus Crew | 1.5 | 0–0 | 1.2 | Philadelphia | 5,180 | MAPFRE Stadium | Ramy Touchan | Match Report | |
|---|
| Regular Season | Sat | 2021-04-17 | 19:00 | FC Dallas | 0.9 | 0–0 | 1.0 | Colorado Rapids | 8,621 | Toyota Stadium | Nima Saghafi | Match Report | |
|---|
| Regular Season | Sat | 2021-04-17 | 19:30 | Nashville | 3.4 | 2–2 | 1.8 | FC Cincinnati | | Nissan Stadium | Rubiel Vazquez | Match Report | |
|---|
| Regular Season | Sat | 2021-04-17 | 19:30 | Chicago Fire | 2.2 | 2–2 | 1.9 | New England | | Soldier Field | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Sat | 2021-04-17 | 20:00 | D.C. United | 0.6 | 2–1 | 1.5 | NYCFC | 4,500 | Audi Field | Ted Unkel | Match Report | |
|---|
| Regular Season | Sat | 2021-04-17 | 20:00 | NY Red Bulls | 0.6 | 1–2 | 1.9 | Sporting KC | | Red Bull Arena | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sun | 2021-04-18 | 20:00 | Vancouver | 0.3 | 1–0 | 1.0 | Portland Timbers | | Rio Tinto Stadium | Allen Chapman | Match Report | |
|---|
| Regular Season | Fri | 2021-04-23 | 18:30 | Sporting KC | 0.7 | 1–1 | 1.3 | Orlando City | | Children's Mercy Park | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sat | 2021-04-24 | 12:30 | San Jose | 2.7 | 3–1 | 1.8 | FC Dallas | | Avaya Stadium | Tim Ford | Match Report | |
|---|
| Regular Season | Sat | 2021-04-24 | 13:00 | NYCFC | 2.0 | 5–0 | 1.1 | FC Cincinnati | | Yankee Stadium | Dave Gantar | Match Report | |
|---|
| Regular Season | Sat | 2021-04-24 | 13:00 | Nashville | 2.5 | 2–2 | 0.8 | CF Montréal | | Nissan Stadium | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Sat | 2021-04-24 | 15:00 | Los Angeles FC | 0.7 | 1–1 | 0.8 | Seattle | | Banc of California Stadium | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sat | 2021-04-24 | 15:00 | Toronto FC | 1.6 | 2–2 | 1.6 | Vancouver | | Exploria Stadium | Jair Marrufo | Match Report | |
|---|
| Regular Season | Sun | 2021-04-25 | 14:30 | LA Galaxy | 2.3 | 3–2 | 1.7 | NY Red Bulls | | Dignity Health Sports Park | Victor Rivas | Match Report | |
|---|
| Regular Season | Sat | 2021-04-24 | 19:00 | Minnesota Utd | 1.4 | 1–2 | 2.2 | Real Salt Lake | 4,100 | Allianz Field | Drew Fischer | Match Report | |
|---|
| Regular Season | Sat | 2021-04-24 | 19:00 | Colorado Rapids | 1.5 | 1–3 | 2.1 | Austin | | Dick's Sporting Goods Park | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sat | 2021-04-24 | 19:30 | Portland Timbers | 2.7 | 2–1 | 1.0 | Houston Dynamo | | Providence Park | Ismail Elfath | Match Report | |
|---|
| Regular Season | Sat | 2021-04-24 | 20:00 | New England | 0.3 | 1–0 | 0.3 | D.C. United | | Gillette Stadium | Guido Gonzalez Jr. | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Sat | 2021-04-24 | 20:00 | Atlanta Utd | 1.7 | 3–1 | 1.3 | Chicago Fire | 20,335 | Mercedes-Benz Stadium | Allen Chapman | Match Report | |
|---|
| Regular Season | Sat | 2021-04-24 | 20:00 | Philadelphia | 1.1 | 1–2 | 0.9 | Inter Miami | 5,000 | Subaru Park | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Sat | 2021-05-01 | 12:00 | Real Salt Lake | 1.3 | 3–1 | 0.5 | Sporting KC | | Rio Tinto Stadium | Dave Gantar | Match Report | |
|---|
| Regular Season | Sat | 2021-05-01 | 13:00 | NY Red Bulls | 1.1 | 2–0 | 0.4 | Chicago Fire | | Red Bull Arena | Ted Unkel | Match Report | |
|---|
| Regular Season | Sat | 2021-05-01 | 14:30 | Houston Dynamo | 0.8 | 1–1 | 1.5 | Los Angeles FC | 7,850 | PNC Stadium | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sat | 2021-05-01 | 15:00 | CF Montréal | 1.4 | 0–0 | 0.2 | Columbus Crew | | Lockhart Stadium | Tim Ford | Match Report | |
|---|
| Regular Season | Sat | 2021-05-01 | 19:00 | New England | 2.5 | 2–1 | 1.3 | Atlanta Utd | | Gillette Stadium | Chris Penso | Match Report | |
|---|
| Regular Season | Sat | 2021-05-01 | 19:30 | Philadelphia | 0.2 | 0–2 | 2.6 | NYCFC | | Subaru Park | Ismail Elfath | Match Report | |
|---|
| Regular Season | Sat | 2021-05-01 | 19:30 | Orlando City | 2.8 | 3–0 | 1.0 | FC Cincinnati | | Exploria Stadium | Drew Fischer | Match Report | |
|---|
| Regular Season | Sun | 2021-05-02 | 12:00 | Nashville | 0.7 | 0–0 | 0.3 | Inter Miami | 13,855 | Nissan Stadium | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-05-01 | 19:00 | Minnesota Utd | 1.0 | 0–1 | 2.3 | Austin | 4,100 | Allianz Field | Ramy Touchan | Match Report | |
|---|
| Regular Season | Sat | 2021-05-01 | 19:00 | FC Dallas | 2.0 | 4–1 | 0.6 | Portland Timbers | 8,621 | Toyota Stadium | Alan Kelly | Match Report | |
|---|
| Regular Season | Sat | 2021-05-01 | 20:00 | San Jose | 1.5 | 4–1 | 1.6 | D.C. United | | Avaya Stadium | Kevin Stott | Match Report | |
|---|
| Regular Season | Sun | 2021-05-02 | 18:00 | Seattle | 2.1 | 3–0 | 1.1 | LA Galaxy | 7,148 | Lumen Field | Jair Marrufo | Match Report | |
|---|
| Regular Season | Sun | 2021-05-02 | 20:00 | Vancouver | 1.0 | 0–1 | 2.0 | Colorado Rapids | | Rio Tinto Stadium | Baldomero Toledo | Match Report | |
|---|
| Regular Season | Sat | 2021-05-08 | 12:00 | Chicago Fire | 1.0 | 0–2 | 1.7 | Philadelphia | 6,457 | Soldier Field | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sat | 2021-05-08 | 12:00 | Vancouver | 1.6 | 2–0 | 1.4 | CF Montréal | | Rio Tinto Stadium | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-05-08 | 12:30 | Nashville | 1.0 | 2–0 | 0.9 | New England | 12,510 | Nissan Stadium | Victor Rivas | Match Report | |
|---|
| Regular Season | Sat | 2021-05-08 | 13:00 | NY Red Bulls | 1.6 | 2–0 | 0.3 | Toronto FC | | Red Bull Arena | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Sat | 2021-05-08 | 13:30 | Columbus Crew | 0.4 | 3–1 | 1.0 | D.C. United | 5,180 | MAPFRE Stadium | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Sat | 2021-05-08 | 14:30 | FC Dallas | 1.4 | 1–1 | 1.5 | Houston Dynamo | 8,749 | Toyota Stadium | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Sat | 2021-05-08 | 18:00 | Orlando City | 0.6 | 1–1 | 1.6 | NYCFC | 11,503 | Exploria Stadium | Robert Sibiga | Match Report | |
|---|
| Regular Season | Fri | 2021-05-07 | 19:30 | Real Salt Lake | 0.9 | 1–2 | 1.6 | San Jose | 10,448 | Rio Tinto Stadium | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Sun | 2021-05-09 | 12:00 | Portland Timbers | 1.7 | 1–2 | 2.3 | Seattle | | Providence Park | Chris Penso | Match Report | |
|---|
| Regular Season | Sun | 2021-05-09 | 13:00 | Inter Miami | 2.4 | 1–1 | 1.3 | Atlanta Utd | 8,074 | Lockhart Stadium | Joe Dickerson | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Sat | 2021-05-08 | 17:00 | LA Galaxy | 0.8 | 2–1 | 1.4 | Los Angeles FC | 7,193 | Dignity Health Sports Park | Allen Chapman | Match Report | |
|---|
| Regular Season | Sun | 2021-05-09 | 18:30 | Sporting KC | 3.4 | 2–1 | 0.7 | Austin | | Children's Mercy Park | Ted Unkel | Match Report | |
|---|
| Regular Season | Sat | 2021-05-08 | 20:00 | Colorado Rapids | 0.9 | 3–2 | 1.1 | Minnesota Utd | | Dick's Sporting Goods Park | Tim Ford | Match Report | |
|---|
| Regular Season | Wed | 2021-05-12 | 19:00 | Toronto FC | 1.4 | 2–0 | 0.7 | Columbus Crew | | Exploria Stadium | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Wed | 2021-05-12 | 19:30 | Philadelphia | 2.1 | 1–1 | 1.4 | New England | 5,000 | Subaru Park | Tori Penso | Match Report | |
|---|
| Regular Season | Wed | 2021-05-12 | 19:30 | Inter Miami | 0.3 | 0–2 | 1.4 | CF Montréal | 8,220 | Lockhart Stadium | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Wed | 2021-05-12 | 19:30 | Houston Dynamo | 1.1 | 1–0 | 1.5 | Sporting KC | 7,054 | PNC Stadium | Chris Penso | Match Report | |
|---|
| Regular Season | Wed | 2021-05-12 | 19:30 | San Jose | 1.8 | 0–1 | 1.1 | Seattle | 5,000 | Avaya Stadium | Baldomero Toledo | Match Report | |
|---|
| Regular Season | Wed | 2021-05-12 | 20:00 | Minnesota Utd | 1.8 | 1–0 | 0.9 | Vancouver | 4,100 | Allianz Field | Jon Freemon | Match Report | |
|---|
| Regular Season | Thu | 2021-05-13 | 20:00 | D.C. United | 1.2 | 1–0 | 1.8 | Chicago Fire | 3,935 | Audi Field | Ramy Touchan | Match Report | |
|---|
| Regular Season | Sat | 2021-05-15 | 12:30 | LA Galaxy | 2.6 | 2–0 | 1.2 | Austin | 7,193 | Dignity Health Sports Park | Kevin Stott | Match Report | |
|---|
| Regular Season | Sat | 2021-05-15 | 13:00 | NYCFC | 1.8 | 1–1 | 0.4 | Toronto FC | | Yankee Stadium | Dave Gantar | Match Report | |
|---|
| Regular Season | Sat | 2021-05-15 | 19:00 | Atlanta Utd | 0.9 | 1–0 | 0.7 | CF Montréal | 40,116 | Mercedes-Benz Stadium | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Sat | 2021-05-15 | 19:30 | Philadelphia | 1.5 | 1–0 | 1.2 | NY Red Bulls | 5,000 | Subaru Park | Allen Chapman | Match Report | |
|---|
| Regular Season | Sun | 2021-05-16 | 13:00 | Sporting KC | 2.9 | 3–0 | 1.1 | Vancouver | | Children's Mercy Park | Alan Kelly | Match Report | |
|---|
| Regular Season | Sun | 2021-05-16 | 16:00 | FC Cincinnati | 1.1 | 2–3 | 1.9 | Inter Miami | 6,000 | West End Stadium | Ramy Touchan | Match Report | |
|---|
| Regular Season | Sun | 2021-05-16 | 18:00 | New England | 1.5 | 1–0 | 0.4 | Columbus Crew | | Gillette Stadium | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sat | 2021-05-15 | 19:00 | Colorado Rapids | 1.7 | 3–1 | 0.3 | Houston Dynamo | | Dick's Sporting Goods Park | Victor Rivas | Match Report | |
|---|
| Regular Season | Sat | 2021-05-15 | 19:00 | Minnesota Utd | 1.8 | 1–0 | 0.9 | FC Dallas | 4,100 | Allianz Field | Ted Unkel | Match Report | |
|---|
| Regular Season | Sat | 2021-05-15 | 19:00 | San Jose | 3.0 | 0–2 | 2.5 | Portland Timbers | | Avaya Stadium | Tim Ford | Match Report | |
|---|
| Regular Season | Sat | 2021-05-15 | 19:30 | Real Salt Lake | 0.6 | 0–0 | 0.7 | Nashville | 10,555 | Rio Tinto Stadium | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sun | 2021-05-16 | 18:30 | Seattle | 1.3 | 2–0 | 0.5 | Los Angeles FC | 7,173 | Lumen Field | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sun | 2021-05-16 | 20:00 | D.C. United | 1.0 | 0–1 | 0.4 | Orlando City | 5,280 | Audi Field | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Sat | 2021-05-22 | 12:30 | Portland Timbers | 3.3 | 3–0 | 1.2 | LA Galaxy | | Providence Park | Alan Kelly | Match Report | |
|---|
| Regular Season | Sat | 2021-05-22 | 13:00 | CF Montréal | 2.9 | 1–2 | 1.4 | FC Cincinnati | | Lockhart Stadium | Fotis Bazakos | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Sat | 2021-05-22 | 17:00 | Chicago Fire | 1.8 | 1–0 | 0.4 | Inter Miami | 10,844 | Soldier Field | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Sat | 2021-05-22 | 19:00 | Orlando City | 2.0 | 1–0 | 1.6 | Toronto FC | 11,525 | Exploria Stadium | Victor Rivas | Match Report | |
|---|
| Regular Season | Sat | 2021-05-22 | 19:30 | NYCFC | 1.3 | 1–2 | 0.6 | Columbus Crew | 3,154 | Red Bull Arena | Drew Fischer | Match Report | |
|---|
| Regular Season | Sun | 2021-05-23 | 13:30 | Seattle | 0.3 | 1–1 | 1.1 | Atlanta Utd | 11,011 | Lumen Field | Kevin Stott | Match Report | |
|---|
| Regular Season | Sat | 2021-05-22 | 19:00 | San Jose | 1.9 | 1–3 | 2.0 | Sporting KC | | Avaya Stadium | Allen Chapman | Match Report | |
|---|
| Regular Season | Sat | 2021-05-22 | 19:00 | FC Dallas | 2.7 | 2–2 | 1.1 | Real Salt Lake | 8,621 | Toyota Stadium | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sun | 2021-05-23 | 19:15 | D.C. United | 1.4 | 0–1 | 1.0 | Philadelphia | 6,200 | Audi Field | Tim Ford | Match Report | |
|---|
| Regular Season | Sat | 2021-05-22 | 19:30 | Los Angeles FC | 1.4 | 2–1 | 1.7 | Colorado Rapids | 10,483 | Banc of California Stadium | Ismail Elfath | Match Report | |
|---|
| Regular Season | Sat | 2021-05-22 | 20:00 | New England | 3.8 | 3–1 | 1.2 | NY Red Bulls | | Gillette Stadium | Jair Marrufo | Match Report | |
|---|
| Regular Season | Sat | 2021-05-22 | 20:00 | Houston Dynamo | 1.1 | 2–1 | 1.1 | Vancouver | 9,255 | PNC Stadium | Dave Gantar | Match Report | |
|---|
| Regular Season | Sun | 2021-05-23 | 20:00 | Nashville | 2.4 | 1–0 | 0.6 | Austin | 22,421 | Nissan Stadium | Chris Penso | Match Report | |
|---|
| Regular Season | Sat | 2021-05-29 | 12:00 | Chicago Fire | 2.0 | 0–1 | 0.6 | CF Montréal | 6,680 | Soldier Field | Victor Rivas | Match Report | |
|---|
| Regular Season | Sat | 2021-05-29 | 13:00 | NY Red Bulls | 1.8 | 2–1 | 1.1 | Orlando City | | Red Bull Arena | Ismail Elfath | Match Report | |
|---|
| Regular Season | Sat | 2021-05-29 | 14:00 | Los Angeles FC | 2.2 | 1–2 | 0.7 | NYCFC | 10,703 | Banc of California Stadium | Kevin Stott | Match Report | |
|---|
| Regular Season | Sat | 2021-05-29 | 15:00 | FC Cincinnati | 0.7 | 0–1 | 1.7 | New England | 11,000 | West End Stadium | Dave Gantar | Match Report | |
|---|
| Regular Season | Sat | 2021-05-29 | 15:00 | Columbus Crew | 1.1 | 2–1 | 1.1 | Toronto FC | 5,700 | MAPFRE Stadium | Allen Chapman | Match Report | |
|---|
| Regular Season | Sat | 2021-05-29 | 15:30 | Atlanta Utd | 1.1 | 2–2 | 1.8 | Nashville | 40,748 | Mercedes-Benz Stadium | Alan Kelly | Match Report | |
|---|
| Regular Season | Sat | 2021-05-29 | 16:00 | LA Galaxy | 1.7 | 1–0 | 2.6 | San Jose | | Dignity Health Sports Park | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sat | 2021-05-29 | 19:00 | Colorado Rapids | 1.9 | 3–0 | 1.4 | FC Dallas | | Dick's Sporting Goods Park | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Sun | 2021-05-30 | 19:00 | Philadelphia | 2.7 | 3–0 | 1.2 | Portland Timbers | 6,635 | Subaru Park | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sat | 2021-05-29 | 19:30 | Real Salt Lake | 0.8 | 1–1 | 0.9 | Minnesota Utd | 10,853 | Rio Tinto Stadium | Jair Marrufo | Match Report | |
|---|
| Regular Season | Sat | 2021-05-29 | 19:30 | Sporting KC | 2.3 | 3–2 | 1.6 | Houston Dynamo | 20,086 | Children's Mercy Park | Drew Fischer | Match Report | |
|---|
| Regular Season | Sat | 2021-05-29 | 20:00 | Inter Miami | 0.7 | 0–3 | 1.6 | D.C. United | | Lockhart Stadium | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sun | 2021-05-30 | 18:30 | Seattle | 0.8 | 0–0 | 0.7 | Austin | 12,895 | Lumen Field | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-06-12 | 14:00 | Sporting KC | 3.1 | 1–1 | 1.7 | Austin | 18,519 | Children's Mercy Park | Robert Sibiga | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Sat | 2021-06-19 | 19:30 | NYCFC | 3.1 | 2–3 | 1.8 | New England | 4,929 | Red Bull Arena | Allen Chapman | Match Report | |
|---|
| Regular Season | Sat | 2021-06-19 | 19:30 | FC Cincinnati | 1.7 | 0–2 | 0.7 | Colorado Rapids | 25,054 | West End Stadium | Baldomero Toledo | Match Report | |
|---|
| Regular Season | Sat | 2021-06-19 | 19:30 | Toronto FC | 2.1 | 2–3 | 1.5 | Orlando City | | Exploria Stadium | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sat | 2021-06-19 | 19:30 | Columbus Crew | 2.3 | 2–0 | 1.0 | Chicago Fire | 20,064 | MAPFRE Stadium | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Fri | 2021-06-18 | 20:00 | Real Salt Lake | 1.2 | 3–1 | 1.1 | Vancouver | 15,109 | Rio Tinto Stadium | Rubiel Vazquez | Match Report | |
|---|
| Regular Season | Fri | 2021-06-18 | 20:00 | NY Red Bulls | 0.9 | 2–0 | 0.6 | Nashville | 10,173 | Red Bull Arena | Nima Saghafi | Match Report | |
|---|
| Regular Season | Sun | 2021-06-20 | 14:00 | Atlanta Utd | 0.9 | 2–2 | 2.1 | Philadelphia | 42,523 | Mercedes-Benz Stadium | Ted Unkel | Match Report | |
|---|
| Regular Season | Sat | 2021-06-19 | 18:00 | LA Galaxy | 1.2 | 1–2 | 1.8 | Seattle | 23,165 | Dignity Health Sports Park | Drew Fischer | Match Report | |
|---|
| Regular Season | Sat | 2021-06-19 | 19:30 | FC Dallas | 0.8 | 1–1 | 2.7 | Minnesota Utd | 16,455 | Toyota Stadium | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sat | 2021-06-19 | 19:30 | Portland Timbers | 1.4 | 2–1 | 1.7 | Sporting KC | | Providence Park | Alan Kelly | Match Report | |
|---|
| Regular Season | Sat | 2021-06-19 | 20:00 | Los Angeles FC | 2.0 | 1–1 | 0.2 | Houston Dynamo | 22,043 | Banc of California Stadium | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sat | 2021-06-19 | 20:00 | D.C. United | 2.8 | 1–0 | 0.7 | Inter Miami | 16 | Audi Field | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Sat | 2021-06-19 | 20:00 | Austin | 1.5 | 0–0 | 0.7 | San Jose | | Q2 Stadium | Ismail Elfath | Match Report | |
|---|
| Regular Season | Tue | 2021-06-22 | 19:30 | Orlando City | 3.1 | 5–0 | 0.7 | San Jose | 15,476 | Exploria Stadium | Chris Penso | Match Report | |
|---|
| Regular Season | Wed | 2021-06-23 | 19:00 | New England | 1.5 | 3–2 | 1.1 | NY Red Bulls | | Gillette Stadium | Robert Sibiga | Match Report | |
|---|
| Regular Season | Wed | 2021-06-23 | 19:30 | NYCFC | 2.4 | 1–0 | 0.4 | Atlanta Utd | 3,564 | Red Bull Arena | Ismail Elfath | Match Report | |
|---|
| Regular Season | Wed | 2021-06-23 | 19:30 | Philadelphia | 0.4 | 1–0 | 0.6 | Columbus Crew | 16,234 | Subaru Park | Joe Dickerson | Match Report | |
|---|
| Regular Season | Wed | 2021-06-23 | 19:00 | Chicago Fire | 1.3 | 0–1 | 2.3 | FC Cincinnati | 5,926 | Soldier Field | Ismir Pekmic | Match Report | |
|---|
| Regular Season | Wed | 2021-06-23 | 19:00 | Seattle | 2.3 | 2–1 | 1.1 | Real Salt Lake | 24,652 | Lumen Field | Ted Unkel | Match Report | |
|---|
| Regular Season | Wed | 2021-06-23 | 19:00 | Minnesota Utd | 1.2 | 2–0 | 0.8 | Austin | 19,209 | Allianz Field | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Wed | 2021-06-23 | 19:30 | Houston Dynamo | 1.3 | 2–2 | 1.3 | Portland Timbers | 10,791 | PNC Stadium | Armando Villarreal | Match Report | |
|---|
| Regular Season | Wed | 2021-06-23 | 19:30 | Sporting KC | 2.2 | 3–1 | 1.3 | Colorado Rapids | 18,690 | Children's Mercy Park | Dave Gantar | Match Report | |
|---|
| Regular Season | Wed | 2021-06-23 | 19:30 | Nashville | 2.7 | 3–2 | 1.2 | Toronto FC | 17,008 | Nissan Stadium | Ramy Touchan | Match Report | |
|---|
| Regular Season | Wed | 2021-06-23 | 19:30 | Los Angeles FC | 2.8 | 2–0 | 0.6 | FC Dallas | 22,510 | Banc of California Stadium | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Wed | 2021-06-23 | 20:00 | CF Montréal | 0.2 | 0–0 | 2.8 | D.C. United | | Lockhart Stadium | Drew Fischer | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Wed | 2021-06-23 | 20:30 | Vancouver | 0.8 | 1–2 | 1.1 | LA Galaxy | | Rio Tinto Stadium | Tori Penso | Match Report | |
|---|
| Regular Season | Sat | 2021-06-26 | 16:30 | Sporting KC | 1.5 | 2–1 | 0.9 | Los Angeles FC | 20,213 | Children's Mercy Park | Chris Penso | Match Report | |
|---|
| Regular Season | Sat | 2021-06-26 | 19:00 | Toronto FC | 0.5 | 0–2 | 1.3 | FC Cincinnati | | Exploria Stadium | Rubiel Vazquez | Match Report | |
|---|
| Regular Season | Fri | 2021-06-25 | 20:00 | Inter Miami | 0.7 | 1–2 | 0.6 | Orlando City | 17,926 | Lockhart Stadium | Allen Chapman | Match Report | |
|---|
| Regular Season | Sun | 2021-06-27 | 15:30 | Atlanta Utd | 1.1 | 0–0 | 0.4 | NY Red Bulls | 42,575 | Mercedes-Benz Stadium | Alan Kelly | Match Report | |
|---|
| Regular Season | Sun | 2021-06-27 | 18:00 | NYCFC | 1.7 | 2–1 | 1.5 | D.C. United | 4,533 | Red Bull Arena | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sat | 2021-06-26 | 18:00 | Real Salt Lake | 1.8 | 1–1 | 0.9 | Houston Dynamo | 13,588 | Rio Tinto Stadium | Nima Saghafi | Match Report | |
|---|
| Regular Season | Sat | 2021-06-26 | 18:00 | Seattle | 2.4 | 2–2 | 1.5 | Vancouver | 25,603 | Lumen Field | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Sat | 2021-06-26 | 19:00 | Chicago Fire | 1.1 | 3–3 | 1.1 | Philadelphia | 7,308 | Soldier Field | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Sat | 2021-06-26 | 19:00 | San Jose | 1.1 | 1–3 | 2.3 | LA Galaxy | 18,000 | Stanford Stadium | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sat | 2021-06-26 | 19:30 | Nashville | 2.1 | 1–1 | 0.8 | CF Montréal | 22,523 | Nissan Stadium | Jon Freemon | Match Report | |
|---|
| Regular Season | Sat | 2021-06-26 | 20:30 | Portland Timbers | 1.2 | 0–1 | 2.5 | Minnesota Utd | | Providence Park | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sun | 2021-06-27 | 19:00 | Austin | 1.0 | 0–0 | 0.9 | Columbus Crew | 20,738 | Q2 Stadium | Ted Unkel | Match Report | |
|---|
| Regular Season | Sun | 2021-06-27 | 20:00 | FC Dallas | 1.3 | 2–1 | 1.3 | New England | 14,889 | Toyota Stadium | Kevin Stott | Match Report | |
|---|
| Regular Season | Thu | 2021-07-01 | 20:30 | Austin | 1.4 | 4–1 | 0.6 | Portland Timbers | 20,738 | Q2 Stadium | Ted Unkel | Match Report | |
|---|
| Regular Season | Sat | 2021-07-03 | 17:00 | Columbus Crew | 1.3 | 2–2 | 1.3 | New England | 20,407 | Lower.com Field | Alan Kelly | Match Report | |
|---|
| Regular Season | Sat | 2021-07-03 | 17:30 | D.C. United | 2.8 | 7–1 | 1.3 | Toronto FC | 14,000 | Audi Field | Lukasz Szpala | Match Report | |
|---|
| Regular Season | Sat | 2021-07-03 | 19:30 | Orlando City | 1.8 | 1–2 | 2.0 | NY Red Bulls | 19,009 | Exploria Stadium | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sat | 2021-07-03 | 19:30 | CF Montréal | 1.8 | 1–0 | 0.3 | Inter Miami | | Red Bull Arena | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-07-03 | 19:00 | Minnesota Utd | 2.8 | 2–2 | 1.0 | San Jose | 19,687 | Allianz Field | Michael Radchuk | Match Report | |
|---|
| Regular Season | Sat | 2021-07-03 | 19:00 | Chicago Fire | 1.4 | 3–0 | 1.1 | Atlanta Utd | 14,898 | Soldier Field | Baldomero Toledo | Match Report | |
|---|
| Regular Season | Sat | 2021-07-03 | 19:00 | Nashville | 1.3 | 1–0 | 0.9 | Philadelphia | 21,822 | Nissan Stadium | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sat | 2021-07-03 | 19:30 | Houston Dynamo | 1.7 | 1–1 | 1.5 | FC Cincinnati | 20,021 | PNC Stadium | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sat | 2021-07-03 | 20:00 | Real Salt Lake | 1.1 | 0–1 | 0.5 | Los Angeles FC | 18,253 | Rio Tinto Stadium | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Sun | 2021-07-04 | 19:00 | Colorado Rapids | 0.9 | 1–1 | 0.7 | Seattle | 17,104 | Dick's Sporting Goods Park | Kevin Stott | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Sun | 2021-07-04 | 19:30 | LA Galaxy | 1.4 | 0–2 | 1.9 | Sporting KC | 23,556 | Dignity Health Sports Park | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Sun | 2021-07-04 | 19:30 | FC Dallas | 1.6 | 2–2 | 1.0 | Vancouver | 19,096 | Toyota Stadium | Ramy Touchan | Match Report | |
|---|
| Regular Season | Wed | 2021-07-07 | 19:00 | New England | 2.4 | 2–3 | 1.3 | Toronto FC | | Gillette Stadium | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Wed | 2021-07-07 | 19:30 | CF Montréal | 2.5 | 2–1 | 1.0 | NYCFC | | Exploria Stadium | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Wed | 2021-07-07 | 18:00 | Seattle | 1.9 | 2–0 | 0.7 | Houston Dynamo | 27,421 | Lumen Field | Robert Sibiga | Match Report | |
|---|
| Regular Season | Wed | 2021-07-07 | 19:00 | Colorado Rapids | 1.9 | 2–0 | 0.6 | Minnesota Utd | | Dick's Sporting Goods Park | Ted Unkel | Match Report | |
|---|
| Regular Season | Wed | 2021-07-07 | 19:00 | Chicago Fire | 1.7 | 3–1 | 2.3 | Orlando City | 8,002 | Soldier Field | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Wed | 2021-07-07 | 19:30 | LA Galaxy | 1.3 | 3–1 | 1.5 | FC Dallas | 16,453 | Dignity Health Sports Park | Alan Kelly | Match Report | |
|---|
| Regular Season | Wed | 2021-07-07 | 20:00 | Vancouver | 1.0 | 0–4 | 3.3 | Real Salt Lake | 12,009 | Rio Tinto Stadium | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Wed | 2021-07-07 | 20:00 | Austin | 0.8 | 0–2 | 1.8 | Los Angeles FC | 20,738 | Q2 Stadium | Ramy Touchan | Match Report | |
|---|
| Regular Season | Fri | 2021-07-09 | 19:30 | FC Cincinnati | 1.0 | 2–2 | 0.8 | Columbus Crew | 25,701 | West End Stadium | Kevin Stott | Match Report | |
|---|
| Regular Season | Thu | 2021-07-08 | 19:30 | Nashville | 2.0 | 2–2 | 0.3 | Atlanta Utd | 22,913 | Nissan Stadium | Joe Dickerson | Match Report | |
|---|
| Regular Season | Thu | 2021-07-08 | 20:00 | NY Red Bulls | 2.0 | 1–1 | 1.0 | Philadelphia | 10,013 | Red Bull Arena | Victor Rivas | Match Report | |
|---|
| Regular Season | Sat | 2021-07-17 | 17:00 | Atlanta Utd | 0.6 | 0–1 | 1.5 | New England | 42,517 | Mercedes-Benz Stadium | Victor Rivas | Match Report | |
|---|
| Regular Season | Sat | 2021-07-17 | 19:30 | Toronto FC | 0.5 | 1–1 | 1.2 | Orlando City | 7,000 | BMO Field | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sat | 2021-07-17 | 19:30 | CF Montréal | 3.2 | 5–4 | 1.4 | FC Cincinnati | | Saputo Stadium | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Sat | 2021-07-17 | 19:30 | Columbus Crew | 0.7 | 2–1 | 1.3 | NYCFC | 19,113 | Lower.com Field | Ramy Touchan | Match Report | |
|---|
| Regular Season | Sat | 2021-07-17 | 19:30 | Philadelphia | 1.6 | 2–1 | 1.4 | D.C. United | 16,821 | Subaru Park | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Sun | 2021-07-18 | 13:00 | Minnesota Utd | 1.8 | 1–0 | 0.6 | Seattle | 19,679 | Allianz Field | Alan Kelly | Match Report | |
|---|
| Regular Season | Sat | 2021-07-17 | 19:00 | Colorado Rapids | 0.8 | 1–1 | 0.5 | San Jose | 14,664 | Dick's Sporting Goods Park | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-07-17 | 19:30 | Portland Timbers | 1.0 | 1–0 | 1.1 | FC Dallas | 23,255 | Providence Park | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sat | 2021-07-17 | 19:30 | Nashville | 2.5 | 5–1 | 1.9 | Chicago Fire | 23,113 | Nissan Stadium | Lukasz Szpala | Match Report | |
|---|
| Regular Season | Sat | 2021-07-17 | 19:30 | Los Angeles FC | 3.9 | 2–1 | 0.6 | Real Salt Lake | 22,490 | Banc of California Stadium | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sat | 2021-07-17 | 20:00 | Vancouver | 1.4 | 2–1 | 0.7 | LA Galaxy | | Rio Tinto Stadium | Ismir Pekmic | Match Report | |
|---|
| Regular Season | Wed | 2021-07-21 | 19:30 | Columbus Crew | 1.1 | 0–0 | 0.4 | Nashville | 18,395 | Lower.com Field | Rosendo Mendoza | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Wed | 2021-07-21 | 19:30 | Toronto FC | 0.3 | 1–1 | 1.7 | NY Red Bulls | | BMO Field | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Wed | 2021-07-21 | 19:30 | NYCFC | 1.8 | 1–0 | 0.5 | CF Montréal | 2,873 | Red Bull Arena | Ted Unkel | Match Report | |
|---|
| Regular Season | Wed | 2021-07-21 | 19:30 | Inter Miami | 0.8 | 0–5 | 2.5 | New England | 13,963 | Lockhart Stadium | Robert Sibiga | Match Report | |
|---|
| Regular Season | Tue | 2021-07-20 | 20:00 | Vancouver | 0.7 | 0–0 | 0.4 | Houston Dynamo | | Rio Tinto Stadium | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Wed | 2021-07-21 | 19:00 | Chicago Fire | 0.8 | 2–2 | 2.2 | D.C. United | 8,306 | Soldier Field | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Wed | 2021-07-21 | 19:00 | Colorado Rapids | 1.0 | 2–0 | 0.8 | FC Dallas | 8,321 | Dick's Sporting Goods Park | Jon Freemon | Match Report | |
|---|
| Regular Season | Thu | 2021-07-22 | 19:30 | Orlando City | 0.9 | 2–1 | 1.3 | Philadelphia | 15,432 | Exploria Stadium | Alan Kelly | Match Report | |
|---|
| Regular Season | Wed | 2021-07-21 | 19:30 | Sporting KC | 2.0 | 1–1 | 1.4 | San Jose | 17,872 | Children's Mercy Park | Joe Dickerson | Match Report | |
|---|
| Regular Season | Wed | 2021-07-21 | 19:30 | Portland Timbers | 0.4 | 2–1 | 1.8 | Los Angeles FC | 23,500 | Providence Park | Victor Rivas | Match Report | |
|---|
| Regular Season | Wed | 2021-07-21 | 20:00 | Real Salt Lake | 0.9 | 2–2 | 0.9 | LA Galaxy | 16,169 | Rio Tinto Stadium | Kevin Stott | Match Report | |
|---|
| Regular Season | Wed | 2021-07-21 | 20:00 | FC Cincinnati | 1.1 | 1–1 | 1.6 | Atlanta Utd | 23,162 | West End Stadium | Tori Penso | Match Report | |
|---|
| Regular Season | Thu | 2021-07-22 | 20:30 | Austin | 0.9 | 0–1 | 0.7 | Seattle | 20,738 | Q2 Stadium | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Sat | 2021-07-24 | 15:30 | Atlanta Utd | 1.8 | 0–1 | 1.2 | Columbus Crew | 67,507 | Mercedes-Benz Stadium | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sun | 2021-07-25 | 18:00 | NYCFC | 3.9 | 5–0 | 0.5 | Orlando City | 13,503 | Yankee Stadium | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sun | 2021-07-25 | 18:00 | New England | 1.1 | 2–1 | 1.5 | CF Montréal | 18,217 | Gillette Stadium | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Sat | 2021-07-24 | 19:00 | San Jose | 0.8 | 1–1 | 0.5 | Houston Dynamo | 12,793 | Avaya Stadium | Ted Unkel | Match Report | |
|---|
| Regular Season | Sat | 2021-07-24 | 19:00 | Minnesota Utd | 2.1 | 2–1 | 0.5 | Portland Timbers | 19,691 | Allianz Field | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sat | 2021-07-24 | 19:00 | Chicago Fire | 3.7 | 1–2 | 0.9 | Toronto FC | 12,288 | Soldier Field | Victor Rivas | Match Report | |
|---|
| Regular Season | Sat | 2021-07-24 | 19:30 | Los Angeles FC | 1.0 | 2–2 | 1.3 | Vancouver | 22,049 | Banc of California Stadium | Kevin Stott | Match Report | |
|---|
| Regular Season | Sun | 2021-07-25 | 19:30 | Inter Miami | 1.0 | 1–1 | 1.5 | Philadelphia | 14,057 | Lockhart Stadium | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sat | 2021-07-24 | 19:30 | Nashville | 1.4 | 3–0 | 0.4 | FC Cincinnati | 23,832 | Nissan Stadium | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Sat | 2021-07-24 | 19:30 | FC Dallas | 1.4 | 4–0 | 1.0 | LA Galaxy | 14,812 | Toyota Stadium | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Sat | 2021-07-24 | 20:00 | Real Salt Lake | 0.8 | 3–0 | 0.3 | Colorado Rapids | 17,325 | Rio Tinto Stadium | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Sun | 2021-07-25 | 18:00 | Seattle | 0.8 | 1–3 | 1.4 | Sporting KC | 32,790 | Lumen Field | Ramy Touchan | Match Report | |
|---|
| Regular Season | Sun | 2021-07-25 | 20:00 | D.C. United | 1.3 | 1–0 | 0.2 | NY Red Bulls | 15,912 | Audi Field | Alan Kelly | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Wed | 2021-07-28 | 19:30 | Los Angeles FC | 1.8 | 2–2 | 1.0 | Minnesota Utd | 22,003 | Banc of California Stadium | Baldomero Toledo | Match Report | |
|---|
| Regular Season | Fri | 2021-07-30 | 19:30 | NYCFC | 3.8 | 4–1 | 1.6 | Columbus Crew | | Yankee Stadium | Alan Kelly | Match Report | |
|---|
| Regular Season | Sat | 2021-07-31 | 14:00 | Seattle | 1.2 | 0–1 | 0.5 | San Jose | 32,704 | Lumen Field | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sat | 2021-07-31 | 18:00 | NY Red Bulls | 1.0 | 2–3 | 2.5 | New England | 13,444 | Red Bull Arena | Ramy Touchan | Match Report | |
|---|
| Regular Season | Fri | 2021-07-30 | 19:00 | LA Galaxy | 2.4 | 4–1 | 1.5 | Portland Timbers | 15,644 | Dignity Health Sports Park | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sat | 2021-07-31 | 19:30 | FC Cincinnati | 1.2 | 0–0 | 0.3 | D.C. United | 25,060 | West End Stadium | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Fri | 2021-07-30 | 20:00 | Orlando City | 2.5 | 3–2 | 0.6 | Atlanta Utd | 18,910 | Exploria Stadium | Rubiel Vazquez | Match Report | |
|---|
| Regular Season | Sun | 2021-08-01 | 18:00 | Philadelphia | 2.0 | 1–1 | 0.2 | Chicago Fire | 16,677 | Subaru Park | Michael Radchuk | Match Report | |
|---|
| Regular Season | Sun | 2021-08-01 | 19:30 | Toronto FC | 0.6 | 1–1 | 1.0 | Nashville | | BMO Field | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Sat | 2021-07-31 | 19:30 | Houston Dynamo | 1.1 | 0–0 | 1.3 | Real Salt Lake | 13,462 | PNC Stadium | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Sat | 2021-07-31 | 19:30 | Sporting KC | 1.3 | 1–2 | 0.9 | FC Dallas | 19,975 | Children's Mercy Park | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Sat | 2021-07-31 | 20:00 | Austin | 0.6 | 0–1 | 1.7 | Colorado Rapids | 20,738 | Q2 Stadium | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sat | 2021-07-31 | 20:00 | Inter Miami | 1.8 | 2–1 | 1.7 | CF Montréal | 14,303 | Lockhart Stadium | Victor Rivas | Match Report | |
|---|
| Regular Season | Sat | 2021-07-31 | 20:00 | Vancouver | 1.6 | 2–2 | 1.2 | Minnesota Utd | | Rio Tinto Stadium | Lukasz Szpala | Match Report | |
|---|
| Regular Season | Wed | 2021-08-04 | 19:00 | New England | 0.5 | 0–0 | 0.5 | Nashville | 10,279 | Gillette Stadium | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Wed | 2021-08-04 | 19:30 | CF Montréal | 1.1 | 2–2 | 1.9 | Atlanta Utd | 11,000 | Saputo Stadium | Dave Gantar | Match Report | |
|---|
| Regular Season | Wed | 2021-08-04 | 19:30 | Philadelphia | 2.4 | 3–0 | 1.4 | Toronto FC | 14,303 | Subaru Park | Ted Unkel | Match Report | |
|---|
| Regular Season | Wed | 2021-08-04 | 19:30 | Columbus Crew | 1.3 | 2–4 | 1.7 | D.C. United | 18,398 | Lower.com Field | Victor Rivas | Match Report | |
|---|
| Regular Season | Wed | 2021-08-04 | 19:00 | Chicago Fire | 0.3 | 0–0 | 1.2 | NYCFC | 8,371 | Soldier Field | Baldomero Toledo | Match Report | |
|---|
| Regular Season | Wed | 2021-08-04 | 19:00 | Seattle | 2.0 | 1–1 | 0.9 | FC Dallas | 31,628 | Lumen Field | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Wed | 2021-08-04 | 19:30 | Portland Timbers | 1.7 | 1–1 | 2.2 | San Jose | 22,233 | Providence Park | Allen Chapman | Match Report | |
|---|
| Regular Season | Wed | 2021-08-04 | 19:30 | Los Angeles FC | 2.3 | 1–4 | 1.4 | Sporting KC | 22,114 | Banc of California Stadium | Alan Kelly | Match Report | |
|---|
| Regular Season | Wed | 2021-08-04 | 19:30 | LA Galaxy | 1.4 | 1–0 | 1.0 | Real Salt Lake | 15,544 | Dignity Health Sports Park | Nima Saghafi | Match Report | |
|---|
| Regular Season | Wed | 2021-08-04 | 20:00 | NY Red Bulls | 2.1 | 0–0 | 0.3 | FC Cincinnati | 9,203 | Red Bull Arena | Jon Freemon | Match Report | |
|---|
| Regular Season | Wed | 2021-08-04 | 20:00 | Austin | 1.6 | 3–2 | 1.1 | Houston Dynamo | 20,738 | Q2 Stadium | Joe Dickerson | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Wed | 2021-08-04 | 20:00 | Orlando City | 0.8 | 1–1 | 0.3 | Inter Miami | 17,966 | Exploria Stadium | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sat | 2021-08-07 | 19:30 | FC Cincinnati | 1.1 | 1–1 | 0.9 | Orlando City | 24,113 | West End Stadium | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Sat | 2021-08-07 | 19:30 | Columbus Crew | 1.7 | 2–3 | 2.5 | Atlanta Utd | 20,094 | Lower.com Field | Allen Chapman | Match Report | |
|---|
| Regular Season | Sun | 2021-08-08 | 16:00 | San Jose | 1.6 | 2–1 | 1.5 | Los Angeles FC | 18,000 | Avaya Stadium | Rubiel Vazquez | Match Report | |
|---|
| Regular Season | Sun | 2021-08-08 | 17:00 | Chicago Fire | 0.7 | 2–1 | 1.4 | NY Red Bulls | 11,894 | Soldier Field | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Sun | 2021-08-08 | 18:00 | Inter Miami | 0.9 | 2–1 | 0.5 | Nashville | 14,062 | Lockhart Stadium | Nima Saghafi | Match Report | |
|---|
| Regular Season | Sun | 2021-08-08 | 18:00 | New England | 2.7 | 2–1 | 1.3 | Philadelphia | 17,054 | Gillette Stadium | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sat | 2021-08-07 | 19:00 | Minnesota Utd | 1.0 | 2–0 | 0.6 | Houston Dynamo | 19,625 | Allianz Field | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Sat | 2021-08-07 | 19:00 | Colorado Rapids | 1.8 | 0–0 | 0.5 | Sporting KC | 11,753 | Dick's Sporting Goods Park | Ted Unkel | Match Report | |
|---|
| Regular Season | Sat | 2021-08-07 | 19:30 | FC Dallas | 0.8 | 2–0 | 1.2 | Austin | 16,625 | Toyota Stadium | Alan Kelly | Match Report | |
|---|
| Regular Season | Sat | 2021-08-07 | 19:30 | Portland Timbers | 2.0 | 3–2 | 2.4 | Real Salt Lake | 23,577 | Providence Park | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-08-07 | 20:00 | Toronto FC | 2.3 | 2–2 | 1.2 | NYCFC | 9,331 | BMO Field | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sun | 2021-08-08 | 17:00 | LA Galaxy | 1.7 | 1–1 | 1.1 | Vancouver | 16,234 | Dignity Health Sports Park | Baldomero Toledo | Match Report | |
|---|
| Regular Season | Sun | 2021-08-08 | 20:00 | D.C. United | 1.6 | 2–1 | 0.9 | CF Montréal | 14,169 | Audi Field | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sat | 2021-08-14 | 17:00 | Minnesota Utd | 1.6 | 0–1 | 1.5 | LA Galaxy | 19,787 | Allianz Field | Joe Dickerson | Match Report | |
|---|
| Regular Season | Fri | 2021-08-13 | 19:30 | San Jose | 0.8 | 0–0 | 0.6 | Vancouver | 11,967 | Avaya Stadium | Tim Ford | Match Report | |
|---|
| Regular Season | Sun | 2021-08-15 | 16:00 | Atlanta Utd | 0.8 | 1–0 | 0.9 | Los Angeles FC | 67,503 | Mercedes-Benz Stadium | Chris Penso | Match Report | |
|---|
| Regular Season | Sun | 2021-08-15 | 17:00 | Chicago Fire | 0.9 | 1–0 | 0.7 | Columbus Crew | 13,005 | Soldier Field | Nima Saghafi | Match Report | |
|---|
| Regular Season | Sun | 2021-08-15 | 18:00 | Nashville | 2.1 | 5–2 | 1.0 | D.C. United | 20,022 | Nissan Stadium | Drew Fischer | Match Report | |
|---|
| Regular Season | Sat | 2021-08-14 | 19:30 | Houston Dynamo | 2.5 | 1–3 | 2.0 | Colorado Rapids | 13,908 | PNC Stadium | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-08-14 | 19:30 | FC Dallas | 2.2 | 0–2 | 0.6 | Sporting KC | 14,133 | Toyota Stadium | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sat | 2021-08-14 | 20:00 | Real Salt Lake | 1.2 | 1–0 | 0.8 | Austin | 17,506 | Rio Tinto Stadium | Dave Gantar | Match Report | |
|---|
| Regular Season | Sat | 2021-08-14 | 20:00 | NYCFC | 2.5 | 2–0 | 0.2 | Inter Miami | | Red Bull Arena | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Sat | 2021-08-14 | 20:00 | CF Montréal | 2.8 | 2–1 | 1.9 | NY Red Bulls | | Saputo Stadium | Allen Chapman | Match Report | |
|---|
| Regular Season | Sat | 2021-08-14 | 20:00 | Toronto FC | 1.3 | 1–2 | 1.1 | New England | | BMO Field | Rubiel Vazquez | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Sun | 2021-08-15 | 19:00 | Portland Timbers | 1.6 | 2–6 | 2.4 | Seattle | 25,218 | Providence Park | Jair Marrufo | Match Report | |
|---|
| Regular Season | Wed | 2021-08-18 | 19:00 | New England | 2.0 | 3–2 | 1.7 | D.C. United | 11,419 | Gillette Stadium | Ted Unkel | Match Report | |
|---|
| Regular Season | Wed | 2021-08-18 | 19:00 | Atlanta Utd | 1.5 | 1–0 | 1.2 | Toronto FC | 42,502 | Mercedes-Benz Stadium | Alan Kelly | Match Report | |
|---|
| Regular Season | Tue | 2021-08-17 | 19:30 | San Jose | 0.2 | 1–1 | 1.3 | Minnesota Utd | 10,353 | Avaya Stadium | Victor Rivas | Match Report | |
|---|
| Regular Season | Wed | 2021-08-18 | 19:30 | FC Cincinnati | 1.0 | 0–0 | 0.3 | CF Montréal | 21,115 | West End Stadium | Ramy Touchan | Match Report | |
|---|
| Regular Season | Tue | 2021-08-17 | 19:30 | LA Galaxy | 1.3 | 1–2 | 2.2 | Colorado Rapids | 15,101 | Dignity Health Sports Park | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Wed | 2021-08-18 | 19:30 | Philadelphia | 0.5 | 1–0 | 0.9 | NYCFC | 15,263 | Subaru Park | Drew Fischer | Match Report | |
|---|
| Regular Season | Wed | 2021-08-18 | 19:30 | Inter Miami | 1.4 | 3–2 | 1.1 | Chicago Fire | 13,196 | Lockhart Stadium | Baldomero Toledo | Match Report | |
|---|
| Regular Season | Wed | 2021-08-18 | 19:30 | FC Dallas | 0.9 | 0–1 | 0.4 | Seattle | 11,535 | Toyota Stadium | Robert Sibiga | Match Report | |
|---|
| Regular Season | Wed | 2021-08-18 | 19:30 | Sporting KC | 1.4 | 1–1 | 1.0 | Portland Timbers | 17,081 | Children's Mercy Park | Ismail Elfath | Match Report | |
|---|
| Regular Season | Wed | 2021-08-18 | 19:30 | Nashville | 0.7 | 1–1 | 0.7 | Orlando City | 13,154 | Nissan Stadium | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Wed | 2021-08-18 | 20:00 | Real Salt Lake | 0.8 | 2–1 | 1.6 | Houston Dynamo | 13,570 | Rio Tinto Stadium | Jair Marrufo | Match Report | |
|---|
| Regular Season | Wed | 2021-08-18 | 20:00 | NY Red Bulls | 0.9 | 1–0 | 1.5 | Columbus Crew | 10,002 | Red Bull Arena | Chris Penso | Match Report | |
|---|
| Regular Season | Wed | 2021-08-18 | 20:00 | Austin | 1.0 | 1–2 | 2.5 | Vancouver | 20,738 | Q2 Stadium | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-08-21 | 14:30 | Minnesota Utd | 2.7 | 0–0 | 1.0 | Sporting KC | | Allianz Field | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sat | 2021-08-21 | 17:30 | Columbus Crew | 1.0 | 1–2 | 1.8 | Seattle | 19,401 | Lower.com Field | Joe Dickerson | Match Report | |
|---|
| Regular Season | Fri | 2021-08-20 | 19:30 | LA Galaxy | 1.2 | 1–2 | 2.0 | San Jose | 17,568 | Dignity Health Sports Park | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sat | 2021-08-21 | 19:00 | Vancouver | 1.5 | 2–1 | 3.9 | Los Angeles FC | | BC Place | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Sat | 2021-08-21 | 19:00 | Colorado Rapids | 1.5 | 2–1 | 1.8 | Real Salt Lake | 13,134 | Dick's Sporting Goods Park | Drew Fischer | Match Report | |
|---|
| Regular Season | Sat | 2021-08-21 | 19:30 | Houston Dynamo | 2.1 | 2–2 | 0.9 | FC Dallas | 13,548 | PNC Stadium | Allen Chapman | Match Report | |
|---|
| Regular Season | Sat | 2021-08-21 | 20:00 | Philadelphia | 1.1 | 1–1 | 1.0 | CF Montréal | 14,794 | Subaru Park | Chris Penso | Match Report | |
|---|
| Regular Season | Sat | 2021-08-21 | 20:00 | New England | 2.3 | 4–1 | 0.9 | FC Cincinnati | 18,268 | Gillette Stadium | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Sat | 2021-08-21 | 20:00 | D.C. United | 2.9 | 1–2 | 1.3 | Atlanta Utd | 17,180 | Audi Field | Nima Saghafi | Match Report | |
|---|
| Regular Season | Sat | 2021-08-21 | 20:00 | Orlando City | 1.0 | 1–0 | 1.1 | Chicago Fire | 15,538 | Exploria Stadium | Tim Ford | Match Report | |
|---|
| Regular Season | Sat | 2021-08-21 | 20:00 | Inter Miami | 2.1 | 3–1 | 0.9 | Toronto FC | 14,897 | Lockhart Stadium | Jair Marrufo | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Sat | 2021-08-21 | 20:00 | Austin | 2.8 | 3–1 | 0.9 | Portland Timbers | 20,738 | Q2 Stadium | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Fri | 2021-08-27 | 18:30 | Columbus Crew | 2.3 | 3–2 | 1.1 | FC Cincinnati | 19,949 | Lower.com Field | Robert Sibiga | Match Report | |
|---|
| Regular Season | Fri | 2021-08-27 | 19:30 | CF Montréal | 2.5 | 3–1 | 0.8 | Toronto FC | | Saputo Stadium | Drew Fischer | Match Report | |
|---|
| Regular Season | Sat | 2021-08-28 | 15:30 | Atlanta Utd | 0.5 | 0–2 | 1.0 | Nashville | 42,506 | Mercedes-Benz Stadium | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-08-28 | 16:00 | Los Angeles FC | 3.0 | 3–3 | 1.2 | LA Galaxy | 22,032 | Banc of California Stadium | Allen Chapman | Match Report | |
|---|
| Regular Season | Sat | 2021-08-28 | 18:00 | NY Red Bulls | 0.9 | 0–1 | 1.1 | Chicago Fire | 12,018 | Red Bull Arena | Victor Rivas | Match Report | |
|---|
| Regular Season | Sat | 2021-08-28 | 19:30 | NYCFC | 2.1 | 2–0 | 0.7 | New England | | Yankee Stadium | Kevin Stott | Match Report | |
|---|
| Regular Season | Fri | 2021-08-27 | 20:30 | Orlando City | 1.9 | 0–0 | 0.6 | Inter Miami | 17,817 | Exploria Stadium | Ismail Elfath | Match Report | |
|---|
| Regular Season | Sat | 2021-08-28 | 20:00 | Houston Dynamo | 0.7 | 1–2 | 1.4 | Minnesota Utd | 14,521 | PNC Stadium | Ted Unkel | Match Report | |
|---|
| Regular Season | Sat | 2021-08-28 | 20:00 | Sporting KC | 1.5 | 1–1 | 2.2 | Colorado Rapids | 19,883 | Children's Mercy Park | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Sat | 2021-08-28 | 20:00 | D.C. United | 2.8 | 3–1 | 0.4 | Philadelphia | 16,593 | Audi Field | Rubiel Vazquez | Match Report | |
|---|
| Regular Season | Sun | 2021-08-29 | 19:00 | Austin | 1.4 | 3–5 | 3.7 | FC Dallas | 20,738 | Q2 Stadium | Jair Marrufo | Match Report | |
|---|
| Regular Season | Sun | 2021-08-29 | 19:00 | Vancouver | 1.7 | 4–1 | 0.7 | Real Salt Lake | 7,503 | BC Place | Ramy Touchan | Match Report | |
|---|
| Regular Season | Sun | 2021-08-29 | 19:30 | Seattle | 1.0 | 0–2 | 1.2 | Portland Timbers | 45,737 | Lumen Field | Alan Kelly | Match Report | |
|---|
| Regular Season | Fri | 2021-09-03 | 18:30 | Nashville | 1.0 | 3–1 | 2.0 | NYCFC | 20,126 | Nissan Stadium | Tim Ford | Match Report | |
|---|
| Regular Season | Fri | 2021-09-03 | 19:30 | Philadelphia | 0.7 | 0–1 | 1.0 | New England | 15,152 | Subaru Park | Jair Marrufo | Match Report | |
|---|
| Regular Season | Sat | 2021-09-04 | 16:00 | Vancouver | 2.0 | 2–1 | 1.6 | Austin | 9,223 | BC Place | Pierre-Luc Lauziere | Match Report | |
|---|
| Regular Season | Fri | 2021-09-03 | 19:00 | Los Angeles FC | 3.3 | 4–0 | 0.5 | Sporting KC | 22,018 | Banc of California Stadium | Drew Fischer | Match Report | |
|---|
| Regular Season | Fri | 2021-09-03 | 19:00 | Houston Dynamo | 1.1 | 0–2 | 1.9 | Portland Timbers | 9,872 | PNC Stadium | Rubiel Vazquez | Match Report | |
|---|
| Regular Season | Sat | 2021-09-04 | 19:30 | Orlando City | 1.4 | 3–2 | 0.8 | Columbus Crew | 15,366 | Exploria Stadium | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sat | 2021-09-04 | 18:00 | Real Salt Lake | 2.7 | 3–2 | 1.3 | FC Dallas | 15,882 | Rio Tinto Stadium | Baldomero Toledo | Match Report | |
|---|
| Regular Season | Sat | 2021-09-04 | 19:00 | San Jose | 1.2 | 0–1 | 1.0 | Colorado Rapids | 14,142 | Avaya Stadium | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sat | 2021-09-04 | 20:00 | FC Cincinnati | 0.7 | 0–1 | 1.1 | Inter Miami | 22,234 | West End Stadium | Lukasz Szpala | Match Report | |
|---|
| Regular Season | Fri | 2021-09-10 | 19:00 | Atlanta Utd | 1.6 | 3–0 | 0.3 | Orlando City | 42,507 | Mercedes-Benz Stadium | Victor Rivas | Match Report | |
|---|
| Regular Season | Sat | 2021-09-11 | 14:00 | Seattle | 1.3 | 1–0 | 0.8 | Minnesota Utd | 33,130 | Lumen Field | Alex Chilowicz | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Sat | 2021-09-11 | 15:30 | Colorado Rapids | 1.5 | 1–1 | 1.2 | LA Galaxy | 11,736 | Dick's Sporting Goods Park | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-09-11 | 19:00 | NY Red Bulls | 0.5 | 1–1 | 1.6 | D.C. United | 12,574 | Red Bull Arena | Robert Sibiga | Match Report | |
|---|
| Regular Season | Fri | 2021-09-10 | 19:00 | Vancouver | 1.0 | 0–1 | 1.2 | Portland Timbers | | BC Place | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sat | 2021-09-11 | 19:00 | New England | 1.4 | 2–1 | 0.7 | NYCFC | 19,481 | Gillette Stadium | Chris Penso | Match Report | |
|---|
| Regular Season | Sat | 2021-09-11 | 19:30 | Houston Dynamo | 1.0 | 3–0 | 0.9 | Austin | 14,070 | PNC Stadium | Ismail Elfath | Match Report | |
|---|
| Regular Season | Sat | 2021-09-11 | 19:30 | Sporting KC | 2.0 | 2–0 | 1.1 | Chicago Fire | 18,467 | Children's Mercy Park | Jon Freemon | Match Report | |
|---|
| Regular Season | Sat | 2021-09-11 | 19:30 | FC Dallas | 1.5 | 1–1 | 1.8 | San Jose | 15,237 | Toyota Stadium | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Sat | 2021-09-11 | 20:00 | CF Montréal | 0.8 | 0–1 | 0.9 | Nashville | | Saputo Stadium | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Sat | 2021-09-11 | 20:00 | Inter Miami | 0.6 | 1–0 | 0.5 | Columbus Crew | 15,014 | Lockhart Stadium | Alan Kelly | Match Report | |
|---|
| Regular Season | Sat | 2021-09-11 | 20:00 | FC Cincinnati | 1.3 | 2–0 | 0.8 | Toronto FC | 22,636 | West End Stadium | Dave Gantar | Match Report | |
|---|
| Regular Season | Sun | 2021-09-12 | 19:30 | Los Angeles FC | 0.9 | 3–2 | 1.1 | Real Salt Lake | 22,130 | Banc of California Stadium | Ted Unkel | Match Report | |
|---|
| Regular Season | Tue | 2021-09-14 | 19:30 | Toronto FC | 0.9 | 0–1 | 1.6 | Inter Miami | 7,970 | BMO Field | Ramy Touchan | Match Report | |
|---|
| Regular Season | Tue | 2021-09-14 | 19:30 | NYCFC | 2.4 | 3–3 | 2.0 | FC Dallas | | Yankee Stadium | Joe Dickerson | Match Report | |
|---|
| Regular Season | Tue | 2021-09-14 | 19:30 | Columbus Crew | 1.8 | 2–1 | 1.3 | NY Red Bulls | 17,358 | Lower.com Field | Jair Marrufo | Match Report | |
|---|
| Regular Season | Wed | 2021-09-15 | 19:00 | Atlanta Utd | 2.0 | 4–0 | 1.3 | FC Cincinnati | 42,501 | Mercedes-Benz Stadium | Drew Fischer | Match Report | |
|---|
| Regular Season | Wed | 2021-09-15 | 19:30 | D.C. United | 2.0 | 3–0 | 1.3 | Chicago Fire | 13,524 | Audi Field | Dave Gantar | Match Report | |
|---|
| Regular Season | Wed | 2021-09-15 | 19:30 | Orlando City | 0.7 | 2–4 | 1.7 | CF Montréal | 14,133 | Exploria Stadium | Rubiel Vazquez | Match Report | |
|---|
| Regular Season | Wed | 2021-09-15 | 19:00 | Portland Timbers | 1.7 | 2–2 | 2.0 | Colorado Rapids | 16,808 | Providence Park | Armando Villarreal | Match Report | |
|---|
| Regular Season | Wed | 2021-09-15 | 19:30 | Sporting KC | 2.4 | 4–0 | 0.8 | Minnesota Utd | 16,888 | Children's Mercy Park | Robert Sibiga | Match Report | |
|---|
| Regular Season | Wed | 2021-09-15 | 19:30 | San Jose | 1.0 | 3–4 | 2.2 | Real Salt Lake | 9,636 | Avaya Stadium | Nima Saghafi | Match Report | |
|---|
| Regular Season | Wed | 2021-09-15 | 19:30 | LA Galaxy | 0.9 | 1–1 | 1.1 | Houston Dynamo | 15,341 | Dignity Health Sports Park | Kevin Stott | Match Report | |
|---|
| Regular Season | Wed | 2021-09-15 | 20:00 | Austin | 1.1 | 1–2 | 2.3 | Los Angeles FC | 20,738 | Q2 Stadium | Tim Ford | Match Report | |
|---|
| Regular Season | Fri | 2021-09-17 | 19:00 | Inter Miami | 0.1 | 0–4 | 2.4 | NY Red Bulls | 18,535 | Lockhart Stadium | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Sat | 2021-09-18 | 15:30 | Atlanta Utd | 3.0 | 3–2 | 1.1 | D.C. United | 42,608 | Mercedes-Benz Stadium | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sat | 2021-09-18 | 19:00 | New England | 2.6 | 1–1 | 1.1 | Columbus Crew | 19,004 | Gillette Stadium | Allen Chapman | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Sat | 2021-09-18 | 19:30 | FC Cincinnati | 0.9 | 1–2 | 1.3 | NYCFC | 21,978 | West End Stadium | Ted Unkel | Match Report | |
|---|
| Regular Season | Sat | 2021-09-18 | 19:30 | Toronto FC | 1.4 | 2–1 | 1.6 | Nashville | 9,892 | BMO Field | Pierre-Luc Lauziere | Match Report | |
|---|
| Regular Season | Sun | 2021-09-19 | 13:00 | CF Montréal | 1.4 | 2–0 | 0.8 | Chicago Fire | | Saputo Stadium | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sun | 2021-09-19 | 16:00 | Philadelphia | 2.1 | 3–1 | 0.6 | Orlando City | 15,032 | Subaru Park | Alan Kelly | Match Report | |
|---|
| Regular Season | Sun | 2021-09-19 | 16:30 | Portland Timbers | 1.5 | 2–1 | 2.1 | Los Angeles FC | 21,311 | Providence Park | Chris Penso | Match Report | |
|---|
| Regular Season | Sat | 2021-09-18 | 19:00 | Minnesota Utd | 1.0 | 3–0 | 0.8 | LA Galaxy | 19,400 | Allianz Field | Jair Marrufo | Match Report | |
|---|
| Regular Season | Sat | 2021-09-18 | 19:00 | Austin | 2.6 | 3–4 | 1.9 | San Jose | 20,738 | Q2 Stadium | Baldomero Toledo | Match Report | |
|---|
| Regular Season | Sat | 2021-09-18 | 19:30 | Real Salt Lake | 1.5 | 1–0 | 0.4 | Seattle | 19,850 | Rio Tinto Stadium | Ismail Elfath | Match Report | |
|---|
| Regular Season | Sat | 2021-09-18 | 20:30 | Houston Dynamo | 2.7 | 3–2 | 1.2 | FC Dallas | 12,353 | PNC Stadium | Victor Rivas | Match Report | |
|---|
| Regular Season | Sun | 2021-09-19 | 19:00 | Colorado Rapids | 1.9 | 1–1 | 0.9 | Vancouver | 8,454 | Dick's Sporting Goods Park | Rubiel Vazquez | Match Report | |
|---|
| Regular Season | Wed | 2021-09-22 | 19:30 | Inter Miami | 0.5 | 1–5 | 3.0 | Nashville | 13,033 | Lockhart Stadium | Jon Freemon | Match Report | |
|---|
| Regular Season | Wed | 2021-09-22 | 19:00 | Chicago Fire | 2.6 | 2–3 | 1.7 | New England | 7,052 | Soldier Field | Lukasz Szpala | Match Report | |
|---|
| Regular Season | Wed | 2021-09-22 | 20:00 | NY Red Bulls | 1.3 | 1–1 | 1.0 | NYCFC | 16,072 | Red Bull Arena | Ismail Elfath | Match Report | |
|---|
| Regular Season | Sat | 2021-09-25 | 15:30 | Philadelphia | 1.3 | 1–0 | 0.2 | Atlanta Utd | | Subaru Park | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sat | 2021-09-25 | 19:00 | New England | 1.2 | 2–1 | 1.6 | Orlando City | 23,506 | Gillette Stadium | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-09-25 | 19:30 | Columbus Crew | 0.8 | 2–1 | 1.2 | CF Montréal | 19,423 | Lower.com Field | Nima Saghafi | Match Report | |
|---|
| Regular Season | Sat | 2021-09-25 | 19:30 | D.C. United | 3.4 | 4–2 | 1.1 | FC Cincinnati | 16,069 | Audi Field | Chris Penso | Match Report | |
|---|
| Regular Season | Sat | 2021-09-25 | 19:30 | NYCFC | 1.3 | 0–1 | 1.5 | NY Red Bulls | | Yankee Stadium | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sun | 2021-09-26 | 12:00 | Chicago Fire | 0.2 | 0–0 | 0.4 | Nashville | 15,915 | Soldier Field | Ismir Pekmic | Match Report | |
|---|
| Regular Season | Sat | 2021-09-25 | 18:00 | Colorado Rapids | 1.0 | 0–0 | 0.3 | Toronto FC | 12,613 | Dick's Sporting Goods Park | Michael Radchuk | Match Report | |
|---|
| Regular Season | Sun | 2021-09-26 | 18:00 | Sporting KC | 0.4 | 1–2 | 1.2 | Seattle | 19,248 | Children's Mercy Park | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sat | 2021-09-25 | 19:00 | Minnesota Utd | 0.8 | 2–0 | 1.1 | Houston Dynamo | 19,471 | Allianz Field | Allen Chapman | Match Report | |
|---|
| Regular Season | Sat | 2021-09-25 | 19:00 | San Jose | 1.5 | 2–0 | 0.9 | Los Angeles FC | 16,927 | Avaya Stadium | Jair Marrufo | Match Report | |
|---|
| Regular Season | Sat | 2021-09-25 | 19:00 | Vancouver | 1.2 | 1–0 | 1.7 | FC Dallas | 16,927 | BC Place | Kevin Stott | Match Report | |
|---|
| Regular Season | Sat | 2021-09-25 | 19:30 | Portland Timbers | 1.9 | 6–1 | 1.6 | Real Salt Lake | 21,579 | Providence Park | Fotis Bazakos | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Sun | 2021-09-26 | 20:30 | Austin | 0.9 | 2–0 | 1.3 | LA Galaxy | | Q2 Stadium | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 19:00 | Atlanta Utd | 2.0 | 1–0 | 0.6 | Inter Miami | 42,519 | Mercedes-Benz Stadium | Ted Unkel | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 19:00 | Toronto FC | 3.6 | 3–2 | 0.5 | FC Cincinnati | 5,110 | BMO Field | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 19:30 | CF Montréal | 1.5 | 1–4 | 1.6 | New England | | Saputo Stadium | Ismail Elfath | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 19:30 | D.C. United | 3.0 | 3–1 | 0.2 | Minnesota Utd | 12,262 | Audi Field | Ramy Touchan | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 19:30 | NY Red Bulls | 0.7 | 1–1 | 0.9 | Philadelphia | 9,193 | Red Bull Arena | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 19:00 | FC Dallas | 1.0 | 1–3 | 1.7 | Sporting KC | 12,387 | Toyota Stadium | Jair Marrufo | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 19:00 | Chicago Fire | 0.9 | 2–0 | 0.7 | NYCFC | 5,593 | Soldier Field | Baldomero Toledo | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 19:00 | Colorado Rapids | 1.1 | 3–0 | 0.6 | Austin | 8,582 | Dick's Sporting Goods Park | Michael Radchuk | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 19:30 | Nashville | 1.7 | 2–2 | 1.2 | Orlando City | 18,648 | Nissan Stadium | Drew Fischer | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 19:30 | Los Angeles FC | 0.9 | 1–2 | 0.9 | Portland Timbers | 22,056 | Banc of California Stadium | Joe Dickerson | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 19:30 | Real Salt Lake | 1.1 | 2–1 | 1.9 | LA Galaxy | 18,121 | Rio Tinto Stadium | Tori Penso | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 19:30 | San Jose | 0.3 | 1–3 | 2.3 | Seattle | 11,361 | Avaya Stadium | Allen Chapman | Match Report | |
|---|
| Regular Season | Wed | 2021-09-29 | 20:00 | Houston Dynamo | 1.8 | 0–0 | 0.2 | Vancouver | 12,114 | PNC Stadium | Alan Kelly | Match Report | |
|---|
| Regular Season | Sat | 2021-10-02 | 14:30 | Austin | 3.5 | 2–1 | 1.1 | Real Salt Lake | | Q2 Stadium | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-10-02 | 19:00 | CF Montréal | 1.5 | 2–1 | 1.5 | Atlanta Utd | | Saputo Stadium | Fotis Bazakos | Match Report | |
|---|
| Regular Season | Sat | 2021-10-02 | 19:30 | FC Cincinnati | 0.4 | 0–1 | 1.0 | NY Red Bulls | 22,141 | West End Stadium | Tim Ford | Match Report | |
|---|
| Regular Season | Sat | 2021-10-02 | 19:30 | Orlando City | 1.4 | 2–1 | 0.5 | D.C. United | 16,848 | Exploria Stadium | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Sun | 2021-10-03 | 12:00 | NYCFC | 1.7 | 0–0 | 0.7 | Nashville | | Red Bull Arena | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sun | 2021-10-03 | 14:30 | Portland Timbers | 1.9 | 1–0 | 0.9 | Inter Miami | 22,006 | Providence Park | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sun | 2021-10-03 | 15:00 | Sporting KC | 3.6 | 4–2 | 1.8 | Houston Dynamo | 17,867 | Children's Mercy Park | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Sun | 2021-10-03 | 16:00 | Philadelphia | 1.2 | 3–0 | 1.6 | Columbus Crew | 15,578 | Subaru Park | Victor Rivas | Match Report | |
|---|
| Regular Season | Sun | 2021-10-03 | 16:00 | Toronto FC | 2.5 | 3–1 | 0.6 | Chicago Fire | | BMO Field | Nima Saghafi | Match Report | |
|---|
| Regular Season | Sat | 2021-10-02 | 19:00 | FC Dallas | 1.0 | 0–0 | 1.5 | Minnesota Utd | 17,231 | Toyota Stadium | Rubiel Vazquez | Match Report | |
|---|
| Regular Season | Sat | 2021-10-02 | 19:00 | Vancouver | 2.3 | 3–0 | 0.4 | San Jose | | BC Place | Pierre-Luc Lauziere | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Sun | 2021-10-03 | 17:00 | LA Galaxy | 1.1 | 1–1 | 1.1 | Los Angeles FC | 25,174 | Dignity Health Sports Park | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sun | 2021-10-03 | 19:00 | Seattle | 1.2 | 3–0 | 1.1 | Colorado Rapids | 31,425 | Lumen Field | Chris Penso | Match Report | |
|---|
| Regular Season | Sat | 2021-10-09 | 18:00 | NY Red Bulls | 1.9 | 1–0 | 0.6 | Inter Miami | 17,516 | Red Bull Arena | Tori Penso | Match Report | |
|---|
| Regular Season | Sun | 2021-10-10 | 15:00 | Minnesota Utd | 1.4 | 1–3 | 2.7 | Colorado Rapids | | Allianz Field | Jon Freemon | Match Report | |
|---|
| Regular Season | Sat | 2021-10-09 | 18:00 | Seattle | 1.6 | 4–1 | 1.7 | Vancouver | 31,842 | Lumen Field | Ted Unkel | Match Report | |
|---|
| Regular Season | Sat | 2021-10-09 | 20:00 | FC Cincinnati | 1.6 | 1–2 | 1.6 | Philadelphia | 21,674 | West End Stadium | Lukasz Szpala | Match Report | |
|---|
| Regular Season | Sat | 2021-10-16 | 12:30 | Los Angeles FC | 2.8 | 3–1 | 2.0 | San Jose | 22,003 | Banc of California Stadium | Alan Kelly | Match Report | |
|---|
| Regular Season | Sat | 2021-10-16 | 13:00 | CF Montréal | 0.6 | 2–2 | 0.2 | Philadelphia | | Saputo Stadium | Pierre-Luc Lauziere | Match Report | |
|---|
| Regular Season | Sat | 2021-10-16 | 18:00 | Columbus Crew | 2.9 | 4–0 | 0.4 | Inter Miami | 19,338 | Lower.com Field | Rubiel Vazquez | Match Report | |
|---|
| Regular Season | Sat | 2021-10-16 | 19:00 | New England | 1.4 | 2–2 | 1.4 | Chicago Fire | 28,414 | Gillette Stadium | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sat | 2021-10-16 | 19:30 | Toronto FC | 1.1 | 0–2 | 1.6 | Atlanta Utd | 7,490 | BMO Field | Tim Ford | Match Report | |
|---|
| Regular Season | Sat | 2021-10-16 | 19:30 | FC Cincinnati | 0.6 | 0–1 | 1.0 | Orlando City | 22,488 | West End Stadium | Marcos de Oliveira | Match Report | |
|---|
| Regular Season | Sat | 2021-10-16 | 19:30 | D.C. United | 0.9 | 0–0 | 0.2 | Nashville | 18,034 | Audi Field | Ismail Elfath | Match Report | |
|---|
| Regular Season | Sun | 2021-10-17 | 13:00 | NY Red Bulls | 1.8 | 1–0 | 0.7 | NYCFC | 18,613 | Red Bull Arena | Jair Marrufo | Match Report | |
|---|
| Regular Season | Sat | 2021-10-16 | 19:30 | Houston Dynamo | 0.9 | 2–1 | 0.8 | Seattle | 14,265 | PNC Stadium | Nima Saghafi | Match Report | |
|---|
| Regular Season | Sat | 2021-10-16 | 19:30 | Real Salt Lake | 1.5 | 3–1 | 0.7 | Colorado Rapids | | Rio Tinto Stadium | Kevin Stott | Match Report | |
|---|
| Regular Season | Sat | 2021-10-16 | 19:30 | LA Galaxy | 3.1 | 2–1 | 0.4 | Portland Timbers | 15,322 | Dignity Health Sports Park | Victor Rivas | Match Report | |
|---|
| Regular Season | Sat | 2021-10-16 | 20:00 | Austin | 1.6 | 0–1 | 1.6 | Minnesota Utd | 20,738 | Q2 Stadium | Michael Radchuk | Match Report | |
|---|
| Regular Season | Sun | 2021-10-17 | 19:00 | Vancouver | 0.8 | 2–1 | 0.4 | Sporting KC | 10,990 | BC Place | Silviu Petrescu | Match Report | |
|---|
| Regular Season | Wed | 2021-10-20 | 19:30 | FC Cincinnati | 2.2 | 3–4 | 2.5 | Chicago Fire | 21,369 | West End Stadium | Jon Freemon | Match Report | |
|---|
| Regular Season | Wed | 2021-10-20 | 19:30 | Inter Miami | 1.7 | 3–0 | 0.7 | Toronto FC | | Lockhart Stadium | Armando Villarreal | Match Report | |
|---|
| Regular Season | Wed | 2021-10-20 | 19:30 | Atlanta Utd | 0.7 | 1–1 | 0.9 | NYCFC | 42,511 | Mercedes-Benz Stadium | Rubiel Vazquez | Match Report | |
|---|
| Regular Season | Wed | 2021-10-20 | 19:30 | D.C. United | 1.9 | 2–3 | 1.5 | New England | 13,387 | Audi Field | Nima Saghafi | Match Report | |
|---|
| Regular Season | Wed | 2021-10-20 | 19:30 | Orlando City | 1.8 | 1–1 | 1.0 | CF Montréal | 15,775 | Exploria Stadium | Robert Sibiga | Match Report | |
|---|
| Regular Season | Wed | 2021-10-20 | 19:00 | FC Dallas | 1.2 | 2–3 | 1.6 | Los Angeles FC | 12,532 | Toyota Stadium | Chris Penso | Match Report | |
|---|
| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Wed | 2021-10-20 | 19:00 | Portland Timbers | 0.8 | 2–3 | 1.4 | Vancouver | 16,722 | Providence Park | Guido Gonzalez Jr. | Match Report | |
|---|
| Regular Season | Wed | 2021-10-20 | 19:00 | Minnesota Utd | 1.8 | 3–2 | 2.2 | Philadelphia | | Allianz Field | Allen Chapman | Match Report | |
|---|
| Regular Season | Wed | 2021-10-20 | 19:00 | Colorado Rapids | 1.0 | 1–1 | 1.3 | Seattle | 9,316 | Dick's Sporting Goods Park | Drew Fischer | Match Report | |
|---|
| Regular Season | Wed | 2021-10-20 | 19:30 | Nashville | 0.6 | 1–1 | 0.5 | Columbus Crew | 18,381 | Nissan Stadium | Alex Chilowicz | Match Report | |
|---|
| Regular Season | Wed | 2021-10-20 | 19:30 | San Jose | 2.7 | 4–0 | 0.7 | Austin | 12,035 | Avaya Stadium | Ismir Pekmic | Match Report | |
|---|
| Regular Season | Wed | 2021-10-20 | 19:30 | Houston Dynamo | 1.7 | 0–3 | 1.6 | LA Galaxy | 13,798 | PNC Stadium | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-10-23 | 12:30 | Seattle | 1.8 | 1–2 | 1.1 | Sporting KC | 32,139 | Lumen Field | Ismail Elfath | Match Report | |
|---|
| Regular Season | Sat | 2021-10-23 | 18:00 | Columbus Crew | 0.6 | 1–2 | 2.5 | NY Red Bulls | 17,891 | Lower.com Field | Alan Kelly | Match Report | |
|---|
| Regular Season | Sat | 2021-10-23 | 19:30 | Toronto FC | 1.8 | 1–1 | 2.0 | CF Montréal | 8,095 | BMO Field | Allen Chapman | Match Report | |
|---|
| Regular Season | Sat | 2021-10-23 | 19:30 | NYCFC | 3.1 | 6–0 | 0.5 | D.C. United | | Yankee Stadium | Joe Dickerson | Match Report | |
|---|
| Regular Season | Sat | 2021-10-23 | 19:30 | Philadelphia | 1.7 | 1–0 | 0.3 | Nashville | 18,575 | Subaru Park | Armando Villarreal | Match Report | |
|---|
| Regular Season | Sun | 2021-10-24 | 16:00 | Austin | 2.3 | 2–1 | 0.6 | Houston Dynamo | | Q2 Stadium | Tim Ford | Match Report | |
|---|
| Regular Season | Sat | 2021-10-23 | 19:00 | Chicago Fire | 2.0 | 1–0 | 1.2 | Real Salt Lake | 31,308 | Soldier Field | Rosendo Mendoza | Match Report | |
|---|
| Regular Season | Sat | 2021-10-23 | 19:00 | Minnesota Utd | 2.1 | 1–1 | 0.6 | Los Angeles FC | 19,406 | Allianz Field | Robert Sibiga | Match Report | |
|---|
| Regular Season | Sat | 2021-10-23 | 19:00 | LA Galaxy | 1.9 | 2–2 | 1.5 | FC Dallas | 15,136 | Dignity Health Sports Park | Baldomero Toledo | Match Report | |
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| Regular Season | Sat | 2021-10-23 | 19:00 | San Jose | 1.1 | 1–1 | 0.7 | Vancouver | 15,025 | Avaya Stadium | Marcos de Oliveira | Match Report | |
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| Regular Season | Sat | 2021-10-23 | 19:00 | Colorado Rapids | 1.7 | 2–0 | 0.3 | Portland Timbers | 12,200 | Dick's Sporting Goods Park | Ted Unkel | Match Report | |
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| Regular Season | Sun | 2021-10-24 | 19:30 | Orlando City | 2.0 | 2–2 | 1.5 | New England | 17,539 | Exploria Stadium | Chris Penso | Match Report | |
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| Regular Season | Sat | 2021-10-23 | 20:00 | Inter Miami | 2.4 | 5–1 | 1.2 | FC Cincinnati | 14,927 | Lockhart Stadium | Drew Fischer | Match Report | |
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| Regular Season | Wed | 2021-10-27 | 19:00 | New England | 1.5 | 1–0 | 0.9 | Colorado Rapids | 10,199 | Gillette Stadium | Victor Rivas | Match Report | |
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| Regular Season | Wed | 2021-10-27 | 19:30 | NYCFC | 2.1 | 1–0 | 0.6 | Chicago Fire | | Red Bull Arena | Fotis Bazakos | Match Report | |
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| Regular Season | Wed | 2021-10-27 | 19:30 | Atlanta Utd | 1.2 | 2–1 | 2.1 | Inter Miami | 42,536 | Mercedes-Benz Stadium | Guido Gonzalez Jr. | Match Report | |
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| Regular Season | Wed | 2021-10-27 | 19:30 | D.C. United | 0.8 | 1–0 | 1.6 | NY Red Bulls | 14,109 | Audi Field | Rubiel Vazquez | Match Report | |
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| Regular Season | Wed | 2021-10-27 | 19:30 | Toronto FC | 1.3 | 2–2 | 2.0 | Philadelphia | 5,026 | BMO Field | Silviu Petrescu | Match Report | |
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| Regular Season | Wed | 2021-10-27 | 19:30 | FC Cincinnati | 2.3 | 3–6 | 2.2 | Nashville | 20,581 | West End Stadium | Ramy Touchan | Match Report | |
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| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Tue | 2021-10-26 | 19:30 | Los Angeles FC | 1.4 | 3–0 | 1.0 | Seattle | 22,030 | Banc of California Stadium | Kevin Stott | Match Report | |
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| Regular Season | Wed | 2021-10-27 | 19:30 | Columbus Crew | 0.8 | 3–2 | 1.6 | Orlando City | 16,676 | Lower.com Field | Joe Dickerson | Match Report | |
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| Regular Season | Wed | 2021-10-27 | 19:00 | Portland Timbers | 3.0 | 2–0 | 1.2 | San Jose | 16,086 | Providence Park | Alex Chilowicz | Match Report | |
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| Regular Season | Wed | 2021-10-27 | 19:00 | FC Dallas | 1.4 | 1–2 | 1.1 | Real Salt Lake | 12,486 | Toyota Stadium | Ismail Elfath | Match Report | |
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| Regular Season | Wed | 2021-10-27 | 19:00 | Vancouver | 1.2 | 2–1 | 1.8 | Minnesota Utd | 10,833 | BC Place | Nima Saghafi | Match Report | |
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| Regular Season | Wed | 2021-10-27 | 19:30 | Sporting KC | 0.6 | 2–0 | 0.7 | LA Galaxy | 18,711 | Children's Mercy Park | Alan Kelly | Match Report | |
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| Regular Season | Sat | 2021-10-30 | 13:30 | Inter Miami | 1.1 | 1–3 | 1.7 | NYCFC | 17,595 | Lockhart Stadium | Rosendo Mendoza | Match Report | |
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| Regular Season | Sat | 2021-10-30 | 13:30 | Real Salt Lake | 2.1 | 3–4 | 2.3 | San Jose | 15,553 | Rio Tinto Stadium | Jon Freemon | Match Report | |
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| Regular Season | Sat | 2021-10-30 | 16:00 | NY Red Bulls | 1.3 | 1–0 | 0.6 | CF Montréal | 16,344 | Red Bull Arena | Chris Penso | Match Report | |
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| Regular Season | Sat | 2021-10-30 | 18:00 | Atlanta Utd | 2.8 | 1–1 | 1.2 | Toronto FC | 43,372 | Mercedes-Benz Stadium | Alex Chilowicz | Match Report | |
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| Regular Season | Sat | 2021-10-30 | 19:30 | D.C. United | 1.0 | 1–3 | 2.2 | Columbus Crew | 16,787 | Audi Field | Drew Fischer | Match Report | |
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| Regular Season | Sun | 2021-10-31 | 12:00 | Minnesota Utd | 1.8 | 2–1 | 0.7 | Sporting KC | | Allianz Field | Victor Rivas | Match Report | |
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| Regular Season | Sun | 2021-10-31 | 14:00 | Houston Dynamo | 0.5 | 0–1 | 0.4 | Colorado Rapids | 14,474 | PNC Stadium | Guido Gonzalez Jr. | Match Report | |
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| Regular Season | Sun | 2021-10-31 | 16:00 | Orlando City | 1.0 | 1–1 | 1.0 | Nashville | 15,959 | Exploria Stadium | Allen Chapman | Match Report | |
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| Regular Season | Sun | 2021-10-31 | 19:30 | Philadelphia | 2.5 | 2–0 | 0.4 | FC Cincinnati | 13,488 | Subaru Park | Fotis Bazakos | Match Report | |
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| Regular Season | Sat | 2021-10-30 | 20:00 | FC Dallas | 1.9 | 2–1 | 0.7 | Austin | 16,080 | Toyota Stadium | Silviu Petrescu | Match Report | |
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| Regular Season | Mon | 2021-11-01 | 19:00 | Seattle | 1.3 | 1–1 | 1.1 | LA Galaxy | 32,781 | Lumen Field | Joe Dickerson | Match Report | |
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| Regular Season | Tue | 2021-11-02 | 19:30 | Los Angeles FC | 3.3 | 1–1 | 1.2 | Vancouver | 22,221 | Banc of California Stadium | Alex Chilowicz | Match Report | |
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| Regular Season | Wed | 2021-11-03 | 19:30 | NY Red Bulls | 1.2 | 0–0 | 0.1 | Atlanta Utd | 15,934 | Red Bull Arena | Alan Kelly | Match Report | |
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| Regular Season | Wed | 2021-11-03 | 19:30 | CF Montréal | 1.0 | 2–0 | 0.6 | Houston Dynamo | | Saputo Stadium | Ted Unkel | Match Report | |
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| Regular Season | Wed | 2021-11-03 | 20:00 | Austin | 1.9 | 3–1 | 0.9 | Sporting KC | 20,738 | Q2 Stadium | Nima Saghafi | Match Report | |
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| Regular Season | Wed | 2021-11-03 | 20:30 | Real Salt Lake | 1.9 | 1–3 | 1.6 | Portland Timbers | 18,405 | Rio Tinto Stadium | Chris Penso | Match Report | |
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| Regular Season | Sun | 2021-11-07 | 14:30 | Nashville | 0.9 | 1–1 | 1.7 | NY Red Bulls | 26,913 | Nissan Stadium | Drew Fischer | Match Report | |
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| Regular Season | Sun | 2021-11-07 | 15:00 | Vancouver | 1.2 | 1–1 | 1.8 | Seattle | 25,117 | BC Place | Fotis Bazakos | Match Report | |
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| Regular Season | Sun | 2021-11-07 | 15:00 | San Jose | 2.0 | 1–1 | 1.3 | FC Dallas | | Avaya Stadium | Victor Rivas | Match Report | |
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| Round | Day | Date | Time | Home | xG | Score | xG | Away | Attendance | Venue | Referee | Match Report | Notes |
| Regular Season | Sun | 2021-11-07 | 15:00 | LA Galaxy | 2.0 | 3–3 | 2.5 | Minnesota Utd | 23,803 | Dignity Health Sports Park | Kevin Stott | Match Report | |
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| Regular Season | Sun | 2021-11-07 | 15:00 | Portland Timbers | 3.9 | 3–0 | 0.5 | Austin | 23,127 | Providence Park | Rosendo Mendoza | Match Report | |
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| Regular Season | Sun | 2021-11-07 | 15:30 | FC Cincinnati | 0.7 | 1–2 | 2.1 | Atlanta Utd | 23,663 | West End Stadium | Nima Saghafi | Match Report | |
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| Regular Season | Sun | 2021-11-07 | 15:30 | Toronto FC | 1.0 | 1–3 | 2.7 | D.C. United | 11,166 | BMO Field | Marcos de Oliveira | Match Report | |
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| Regular Season | Sun | 2021-11-07 | 15:30 | CF Montréal | 1.7 | 0–2 | 0.8 | Orlando City | | Saputo Stadium | Armando Villarreal | Match Report | |
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| Regular Season | Sun | 2021-11-07 | 15:30 | Columbus Crew | 3.2 | 2–0 | 0.6 | Chicago Fire | 19,351 | Lower.com Field | Tim Ford | Match Report | |
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| Regular Season | Sun | 2021-11-07 | 15:30 | New England | 1.9 | 0–1 | 0.5 | Inter Miami | 31,635 | Gillette Stadium | Alan Kelly | Match Report | |
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| Regular Season | Sun | 2021-11-07 | 15:30 | NYCFC | 0.5 | 1–1 | 1.8 | Philadelphia | | Yankee Stadium | Guido Gonzalez Jr. | Match Report | |
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| Regular Season | Sun | 2021-11-07 | 16:00 | Colorado Rapids | 2.7 | 5–2 | 1.5 | Los Angeles FC | 16,292 | Dick's Sporting Goods Park | Allen Chapman | Match Report | |
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| Regular Season | Sun | 2021-11-07 | 17:00 | Sporting KC | 1.1 | 0–1 | 1.4 | Real Salt Lake | 19,022 | Children's Mercy Park | Ted Unkel | Match Report | |
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| First Round | Sat | 2021-11-20 | 14:30 | Philadelphia | 2.1 | 1–0 | 0.9 | NY Red Bulls | 18,623 | Subaru Park | Fotis Bazakos | Match Report | Required Extra Time |
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| First Round | Sat | 2021-11-20 | 16:00 | Sporting KC | 1.4 | 3–1 | 1.0 | Vancouver | 19,817 | Children's Mercy Park | Alan Kelly | Match Report | |
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| First Round | Sun | 2021-11-21 | 14:30 | Portland Timbers | 2.3 | 3–1 | 1.6 | Minnesota Utd | 22,533 | Providence Park | Armando Villarreal | Match Report | |
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| First Round | Sun | 2021-11-21 | 15:00 | NYCFC | 0.9 | 2–0 | 0.4 | Atlanta Utd | 25,267 | Yankee Stadium | Chris Penso | Match Report | |
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| First Round | Tue | 2021-11-23 | 19:00 | Nashville | 0.5 | 3–1 | 0.5 | Orlando City | 26,043 | Nissan Stadium | Ismail Elfath | Match Report | |
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| First Round | Tue | 2021-11-23 | 19:30 | Seattle | 1.2 | (5) 0–0 (6) | 0.0 | Real Salt Lake | 34,012 | Lumen Field | Joe Dickerson | Match Report | Real Salt Lake won on penalty kicks following extra time |
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| Conference Semifinals | Thu | 2021-11-25 | 14:30 | Colorado Rapids | 0.8 | 0–1 | 1.2 | Portland Timbers | 17,438 | Dick's Sporting Goods Park | Ted Unkel | Match Report | |
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| Conference Semifinals | Sun | 2021-11-28 | 14:00 | Sporting KC | 1.0 | 1–2 | 1.0 | Real Salt Lake | 21,650 | Children's Mercy Park | Kevin Stott | Match Report | |
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| Conference Semifinals | Sun | 2021-11-28 | 17:30 | Philadelphia | 2.3 | (2) 1–1 (0) | 1.0 | Nashville | 19,076 | Subaru Park | Allen Chapman | Match Report | Philadelphia won on penalty kicks following extra time |
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| Conference Semifinals | Tue | 2021-11-30 | 19:30 | New England | 1.2 | (3) 2–2 (5) | 1.6 | NYCFC | 25,509 | Gillette Stadium | Drew Fischer | Match Report | NYCFC won on penalty kicks following extra time |
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| Conference Finals | Sat | 2021-12-04 | 15:30 | Portland Timbers | 1.5 | 2–0 | 0.4 | Real Salt Lake | | Providence Park | Alan Kelly | Match Report | |
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| Conference Finals | Sun | 2021-12-05 | 15:00 | Philadelphia | 0.4 | 1–2 | 1.4 | NYCFC | 19,487 | Subaru Park | Ted Unkel | Match Report | |
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| MLS Cup | Sat | 2021-12-11 | 12:00 | Portland Timbers | 1.7 | (2) 1–1 (4) | 0.6 | NYCFC | 25,218 | Providence Park | Armando Villarreal | Match Report | NYCFC won on penalty kicks following extra time |
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